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Maca has an excellent safety profile and we can take comfort in the fact that it has been eaten as a food for probably millennia by the Peruvians and Bolivians. It has been placed fresh on foods by the natives as well as cooked in various dishes. Peruvians consider it a food, although they recognize its "medicinal powers" as well. The only caution that I know regarding Maca is that one study on Maca showed a moderate increase in blood pressure at the relatively low dose of just 600 mg/day.  (Of course, work with your doctor whenever trying a new program or supplement.)
I take organic Maca from Navitas: Navitas Naturals Organic Raw Maca Powder and have had good results with it. I always cook it, usually through throwing it in my oatmeal.
Some people have trouble digesting the starch of the maca root, which can lead to stomach upset, gas and/or diahrrea. If this is an issue for you, you can order the gelatinized form, which is usually in the human studies by the way: Maca Power - 100% Certified Organic "Gelatinized" Maca. My understanding is that simple cooking does not break down these starches sufficiently for those who have trouble, whereas the gelatinized version handles that for you.
I should also forewarn you that Maca has a strong taste that is completely quite different from anything else you have probably eaten. I don't find the flavor objectionable but many people do. For many guys, though, the benefits far outweigh its strong aftertaste.
CAUTION: Maca is generally one of the most well-received supplements - although really it could be considered a food like fenugreek - on the forum and in emails. For example, this forum poster lists it as his favorite. However, I did get one forum poster who said that Maca gave him issues and actually lowered his libido and another that said it lowered his testosterone. You can read about that here. Maca reportedly can be stimulating for some and so some men cycle it, i.e. four or five days consuming Maca and a few days of rest afterwards.
Also, it is worth noting that some supplement manufacturers put Maca and Horny Goat Weed together in the same capsule taking advantage of their complementary effects on male physiology. Horny Goat Weed directly boosts Nitric Oxide and boost libido. Maca, through a complete different pathway, boosts semen volume and libido. It is a good combination that does work well for many guys, but you want to get a formulation that has an extract of Icariin (for the Nitric Oxide) and 500 mg of the Maca.
CAUTION: If you have a medical condition or are on any medications, please discuss any changes with your doctor first. Certain supplements, foods and even juices can alter absorption rates of certain medications for example. Play it safe.
1) Urology,2000,55:598-602;J Ethnopharmacol,2001,75:225-9
2) Asian J Androl,Dec 2001,3:301-303
3) Food and Chemical Toxicology, Mar 2008, 46(3):1006-1013, "Maca (Lepidium meyenii) and yacon (Smallanthus sonchifolius) in combination with silymarin as food supplements: In vivo safety assessment"
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