This is a quick review as to how one reader believed Priligy (dapoxetine) overcame
his erectile issues. Now keep in mind that this class of drugs,
is filled with negative side effects and will likely cause long term health
issues. Furthermore, Priligy is not even approved yet in the U.S. for any
However, I did want to discuss what this reader wrote - I got his permission of
course - because his reported results were so dramatic and it brings up some
issues with respect to psychogenic (psychological) erectile dysfunction.
Here is what he wrote. You'll immediately notice the enthusiasm:
READER: "First let me tell you about Dapoxetine (brand name
Priligy). See, I can get a full erection with stimulation, I just can't keep it for more than 5
seconds without stimulation. I also have to stay on the edge of climax to have
and maintain a full erection, problem has been that when I'm inside a woman and
I get to the point of climax I have to slow down."
"The problem with this is that sometimes slowing down means my erection starts
to go way, then it becomes clear that I'm losing my erection while inside a
woman, it becomes psychological and then the battle is lost."
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"Met a very fun and open minded girl, took a 10mg dose of Cialis and a 30mg dose
of Dapoxetine before sex, this time instead of having to slow down and risk
losing my erection, I was able to just keep going, and going, and going. It was
the first time in about 7 or 8 years that I've really been able to knock a
woman's socks off sexually."
So what is Priligy? Could it really have cured 7 or 8 years of erectile
What is interesting is that Priligy is actually used in much of Europe for
premature ejaculation, not erectile dysfunction, and it has several studies
behind it in this area.  Furthermore, Priligy is an SSRI and SSRI's are
notorious for actually causing erectile dysfunction. In fact, seratonin is
actually a vasoconstrictor, i.e. it will often contract your arteries and reduce
blood flow (to your penis). 
All of that said, though, one cannot help but wonder if there is something
unique about this drug that may be applicable to certain men. The reader's
comments indicate that psychogenic (psychological) issues definitely played a
role in his erectile dysfunction. One of the most misunderstood
aspects of an erection is the mental and nervous system component and we can
only hope that more research will follow in these areas.
CAUTIONS: This drug does have significant reported side effects: "common adverse
events (30 mg and 60 mg dapoxetine, respectively) were nausea (8·7%, 20·1%),
diarrhoea (3·9%, 6·8%), headache (5·9%, 6·8%), and dizziness (3·0%, 6·2%)." 
In addition, some experts feel that SSRI's can raise cortisol and, in the long
term, potentially damage arteries.
Ther Clin Risk Manag, 3(2):277–89. "Dapoxetine, a novel selective serotonin
transport inhibitor for the treatment of premature ejaculation".
2) The Lancet, Sep 2006, 368(9539):929-937, "Efficacy and tolerability of
dapoxetine in treatment of premature ejaculation: an integrated analysis of two
double-blind, randomised controlled trials"
3) Journal of Clinical Psychiatry, Feb 1993, 54(2):71-72, "Vasoconstrictive
effects and SSRIs"