Based on what PeakT has said it would be really surprising if TRT gave you that kind of reduction. I'm inclined to be a little suspicious of the high reading from Quest. My own measurements didn't budge after starting TRT. It's been 41-44 nmol/L every time. These include both Quest and LabCorp results.
My understanding is that when T levels increase, SHBG levels decrease for us high SHBG guys. My labs support this. Here are some examples:
DATE: TOTAL T: FREE T: SHBG:
1/12/16 785 10.2 104
4/14/16 1206 18.2 65
6/09/16 1299 23.2 78
All blood test done at Labcorp. Did notice a slight jump in SHBG from 4/14 to 6/09 however, my free t jumped as well. Went from 1.3% of T on 1/12 to
1.8% on 6/09.
That is a pretty dramatic change as well. Maybe it is the TRT.
@cataceous: I had another draw from Quest back in Aug 2015. It was 66 (range 10-50). Not as high as 95 but still pretty high.
@Anemos: I don't know if I have always been high, but most of my readings before the latest one were pretty elevated.
@Peak: Can't think of any other changes that would affect the liver. I was taking DHEA the whole time. But I did switch from OTC DHEA and pregnenalone to the stuff that Defy gives out. Other than that my meds were the same. I definitely was not losing weight. Wasn't gaining either.