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Author Topic: Maximum safe weekly cypionate dosage.  (Read 3337 times)

sh1209

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Maximum safe weekly cypionate dosage.
« on: November 30, 2016, 09:05:19 pm »
I feel fantastic whever I do 120mg per week. This amount bring me in at 1015 on day seven. My levels have always stayed  pretty consistent  during the  week.so I don't think my peak is going much higher. Hematacrit stays around 47 no matter what. Just curious if anyone has to inject that much to feel good.

Boxcar

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Re: Maximum safe weekly cypionate dosage.
« Reply #1 on: November 30, 2016, 10:58:20 pm »
I feel fantastic whever I do 120mg per week. This amount bring me in at 1015 on day seven. My levels have always stayed  pretty consistent  during the  week.so I don't think my peak is going much higher. Hematacrit stays around 47 no matter what. Just curious if anyone has to inject that much to feel good.

The dose isn't unreasonable, nor is 1,015 (assuming you're not going more than 200 higher than that).  But keep in mind that you will increase for 6 weeks after starting a new dose (with most of the increase happening in the first half of that).
Age: 36
178 lbs 5'8''

Current Treatment: 50 mg testosterone cypionate IM, twice a week
Low T Symptoms: Chronic pelvic pain, and other neuropathic pain.  Mild anxiety, low energy and low motivation
Meds: Amitriptyline (for pain, not depression), Clonidine (for sleep, not blood pressure)

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Re: Maximum safe weekly cypionate dosage.
« Reply #1 on: November 30, 2016, 10:58:20 pm »

cujet

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Re: Maximum safe weekly cypionate dosage.
« Reply #2 on: December 01, 2016, 05:11:54 am »
I can't use quite that much. But also I don't sleep well when my levels are at 1200 or more. I'm more of an 80-100/week guy. (Using topical compounded cream now)
54 years old
Autoimmune Hashimoto's, near zero natural T production
Cause: severe mononucleosis in my early 30's
Weight 200
Height 5' 10"
Very active, daily workouts and some cardio.
Topical 0.75g compounded 10% T cream, rotated daily to shaved armpits, shaved shoulders, remainder on scrotum
190mg NPthyroid (natural dessicated pigs thyroid)
Labs (Oct 2017) , my T=730, TSH 0.03, T3+T4 mid-range normal.


Daily workouts with weights, low-glycemic diet, high in clean protein, very low carb (salad/fish/low fat meats, uncooked veggies, nothing else, ever) Carbs/starch can cause me to have intestinal problems, so I avoid them.

PeakT

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Re: Maximum safe weekly cypionate dosage.
« Reply #3 on: December 01, 2016, 07:15:09 am »
Yeah that wired me going over 1200.  I was even short tempered.
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If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

sh1209

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Re: Maximum safe weekly cypionate dosage.
« Reply #4 on: December 01, 2016, 07:19:31 am »
120 put my free test at 22 on day seven. If my total goes below 700 free is off the chart low usually 6-8 and like 1% of total.

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Re: Maximum safe weekly cypionate dosage.
« Reply #4 on: December 01, 2016, 07:19:31 am »


croaker24

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Re: Maximum safe weekly cypionate dosage.
« Reply #5 on: December 01, 2016, 08:04:01 am »
I can't use quite that much. But also I don't sleep well when my levels are at 1200 or more. I'm more of an 80-100/week guy. (Using topical compounded cream now)

Same here.   I was hitting 1200 @ 100 mg /week.   I felt edgy and tight.   Going down to 80 mg / week brought me down to the 800's and I feel far more calm.

sh1209

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Re: Maximum safe weekly cypionate dosage.
« Reply #6 on: December 01, 2016, 08:16:23 am »
What's your trough level at 80

croaker24

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Re: Maximum safe weekly cypionate dosage.
« Reply #7 on: December 01, 2016, 12:28:01 pm »
What's your trough level at 80

The mid 700's last time out.     Next test is January.

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Re: Maximum safe weekly cypionate dosage.
« Reply #7 on: December 01, 2016, 12:28:01 pm »

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sh1209

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Re: Maximum safe weekly cypionate dosage.
« Reply #8 on: December 01, 2016, 12:46:03 pm »
Are u injecting once a week and is your free t good?

croaker24

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Re: Maximum safe weekly cypionate dosage.
« Reply #9 on: December 01, 2016, 03:42:10 pm »
Are u injecting once a week and is your free t good?


Twice a week - Sat PM/Wed AM - 40 mg each time.     I started with Androgel  May 2013 and was consistently in the upper 400's; I was up and down, I had some really awful days, brain fog/fatigue, etc.    Started injections July 2014, twice a week 50 mg and did until Nov 2015, and my trough consistently climbed, to the 800's, 900's, over 1000, and then over 1200.   As the trough climbed, I just felt increasingly on edge, tense, unable to relax, jittery.    Went down to 40 mg/week end of Nov 2015; and began to felt more calm, relaxed.   

The one constant is my DHT has consistently remained at the top of the range, not so sure that is a good thing over a long period of time.

sh1209

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Re: Maximum safe weekly cypionate dosage.
« Reply #10 on: December 01, 2016, 04:05:22 pm »
Thanks for the info. One other question I have is what's your shbg level.

croaker24

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Re: Maximum safe weekly cypionate dosage.
« Reply #11 on: December 01, 2016, 04:38:20 pm »
Thanks for the info. One other question I have is what's your shbg level.

My last draw was May 2016:

Total T - 800   ng/dL
SHBG  -  54.5  nmol/L   range:  19.3 - 76.4
free T  -  12.9  pg/mL    range:  7.2 - 24.0
Estradiol (sensitive)  31.1 pg/mL   range  8.0 - 35.0

Note my estradiol was up to the 49 range before I dialed down the T dosage.


sh1209

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Re: Maximum safe weekly cypionate dosage.
« Reply #12 on: December 01, 2016, 05:10:46 pm »
That's interesting. Your shbg is even higher than mine. I've nearly always injected once per week. Most doctors like Crisler say men with high shbg should inject larger once weekly injections to overcome the shbg. I think I should try the twice weekly protocol just to see if it gives more consistently since of wellbeing. I've had a few other guys on here saying they do very good on twice weekly as well who also have elevated shbg.

croaker24

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Re: Maximum safe weekly cypionate dosage.
« Reply #13 on: December 01, 2016, 06:30:42 pm »
That's interesting. Your shbg is even higher than mine. I've nearly always injected once per week. Most doctors like Crisler say men with high shbg should inject larger once weekly injections to overcome the shbg. I think I should try the twice weekly protocol just to see if it gives more consistently since of well being. I've had a few other guys on here saying they do very good on twice weekly as well who also have elevated shbg.

I went back to look at previous blood draws and my SHBG has been very consistent in the 51-55 range for over 2 years.    What is considered to be "high" SHBG though?   Everyone is different.

Not to mention that in the 3 years I've been on TRT, there's been any number of paradigm shifts.     When I first started, I saw a lot of guys taking an AI to try and keep their estradiol in the low 20's because that was the rule of thumb.    Then there's been the change in injection frequency from every 2 weeks, to weekly, and now we see 2x a week or more often - whatever makes you feel best.
Now it seems that some of better TRT docs are starting patients at lower doses of cypionate a week, I think 50 or 60 mg; where 100 mg/weekly starting was the standard.   

There's no boilerplate for TRT in terms of the protocol or the lab numbers.   Every single patient needs their own fine-tuned strategy - and that strategy is strongly influenced by your health:  physical, mental, and emotional; and your lifestyle:  weight, diet, exercise; and so on ad nauseum.    I've never taken an AI, and I have not tried HCG.    No cialis or viagra.     I don't aim for any kind of perfection - "good enough" is satisfactory for me, so I tend to avoid the over-analysis of the numbers and stick patiently to the protocol.   

You know I work as a software engineer - there was an adage - "If it ain't broke dont' fix it" - that some old-timers would cite, but I was always looking for continuous improvement, and sometimes taking some risks.   With my health, I stick to that adage as for as the TRT protocol goes, but the continuous improvement comes from diet/exercise/stress reduction/etc.    I've seen guys mess with their protocol trying to do "better", but the change makes them feel worse, then they cannot get back to where they were.     


   

PeakT

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Re: Maximum safe weekly cypionate dosage.
« Reply #14 on: December 01, 2016, 06:56:07 pm »
That's interesting. Your shbg is even higher than mine. I've nearly always injected once per week. Most doctors like Crisler say men with high shbg should inject larger once weekly injections to overcome the shbg. I think I should try the twice weekly protocol just to see if it gives more consistently since of wellbeing. I've had a few other guys on here saying they do very good on twice weekly as well who also have elevated shbg.

Sure, but Dr. Crisler I feel certain would also go by how the patient feels. 
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program.aspx
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

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Re: Maximum safe weekly cypionate dosage.
« Reply #14 on: December 01, 2016, 06:56:07 pm »