That's interesting. Your shbg is even higher than mine. I've nearly always injected once per week. Most doctors like Crisler say men with high shbg should inject larger once weekly injections to overcome the shbg. I think I should try the twice weekly protocol just to see if it gives more consistently since of well being. I've had a few other guys on here saying they do very good on twice weekly as well who also have elevated shbg.
I went back to look at previous blood draws and my SHBG has been very consistent in the 51-55 range for over 2 years. What is considered to be "high" SHBG though? Everyone is different.
Not to mention that in the 3 years I've been on TRT, there's been any number of paradigm shifts. When I first started, I saw a lot of guys taking an AI to try and keep their estradiol in the low 20's because that was the rule of thumb. Then there's been the change in injection frequency from every 2 weeks, to weekly, and now we see 2x a week or more often - whatever makes you feel best.
Now it seems that some of better TRT docs are starting patients at lower doses of cypionate a week, I think 50 or 60 mg; where 100 mg/weekly starting was the standard.
There's no boilerplate for TRT in terms of the protocol or the lab numbers. Every single patient needs their own fine-tuned strategy - and that strategy is strongly influenced by your health: physical, mental, and emotional; and your lifestyle: weight, diet, exercise; and so on ad nauseum. I've never taken an AI, and I have not tried HCG. No cialis or viagra. I don't aim for any kind of perfection - "good enough" is satisfactory for me, so I tend to avoid the over-analysis of the numbers and stick patiently to the protocol.
You know I work as a software engineer - there was an adage - "If it ain't broke dont' fix it" - that some old-timers would cite, but I was always looking for continuous improvement, and sometimes taking some risks. With my health, I stick to that adage as for as the TRT protocol goes, but the continuous improvement comes from diet/exercise/stress reduction/etc. I've seen guys mess with their protocol trying to do "better", but the change makes them feel worse, then they cannot get back to where they were.