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Author Topic: Why/How does Viagra raise Testosterone?  (Read 4026 times)

PakMan

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Why/How does Viagra raise Testosterone?
« on: January 07, 2018, 09:22:09 am »
If you look at this study on the libido enhancing effects of Allium Tubersome (ATB) they compared it against Viagra. Only the highest doses of ATB come close to Viagras effect on T/FSH/DHT.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709831/


So how does V raise T?
Age: 46, HT: 5' 7'', WT: 75 kg

Jan 16 to Oct 16 - Test Enanthate (35mg 2x/week)
Oct 16 to Feb 17 - HCG (500iu 2x/Week)
Feb 17 - Test Propionate (25mg only 2 injections 4 days apart)
Aug 2017 onwards (Astaxanthin + other oils, supplements)
Dec 2017 Low dose TRT (25 mg twice a week)




21/08/2017 8:10 PM
Total T = 271 ng/dl  (Range 160 - 726)
LH = 5.15 mIU/ml  (Range 0.8 - 7.6)

Cataceous

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Re: Why/How does Viagra raise Testosterone?
« Reply #1 on: January 07, 2018, 10:48:04 am »
This article has a couple ideas. The underlying references have more details.

Quote
For example, this study conducted back in 2010, found out that sildenafil (the active ingredient in Viagra) was able to increase testosterone levels via elevating the levels of cAMP in isolated rat leydig cells. cAMP is a messenger between cells and hormones and elevated levels of cAMP in the body have been linked to increase testosterone levels. This is similar to how forskolin increases testosterone too.
...

In a study on men:

Quote

Total testosterone rose by 40% (103 ng/dl), free testosterone rose by 50%, and DHT levels also increased significantly (as to be expected when testosterone rises).

Spitzer was not exactly sure why this massive increase took place, but he believes that its caused by some sort of direct response mechanism in the testicles as the serum luteinizing hormone (LH) actually decreased. The decrease in LH also means that the increase in testosterone is not caused by the fact that the subjects probably had more sex during the trial.
...
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 56, Ht: 5'10", Wt: 154 lbs
Protocol: 18 mg T cyptionate subQ qod, 250 IU hCG subQ qod, 6.25 mg DHEA orally bid, 7.5 mg preg. orally qd
5/2017 test results: TT: 800 ng/dL (348-1197), FT: 16 pg/mL (7.2-24), E2: 50 pg/mL sensitive (8.0-35.0), DHEA-S: 278 ug/dL (71.6-375.4)

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Re: Why/How does Viagra raise Testosterone?
« Reply #1 on: January 07, 2018, 10:48:04 am »

PeakT

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Re: Why/How does Viagra raise Testosterone?
« Reply #2 on: January 08, 2018, 10:21:49 am »
If you look at this study on the libido enhancing effects of Allium Tubersome (ATB) they compared it against Viagra. Only the highest doses of ATB come close to Viagras effect on T/FSH/DHT.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709831/


So how does V raise T?

Probably for the same reason I give here:

http://www.peaktestosterone.com/Cialis_Long_Term.aspx
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program.aspx
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Cataceous

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Re: Why/How does Viagra raise Testosterone?
« Reply #3 on: January 08, 2018, 10:49:37 am »
If you look at this study on the libido enhancing effects of Allium Tubersome (ATB) they compared it against Viagra. Only the highest doses of ATB come close to Viagras effect on T/FSH/DHT.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709831/


So how does V raise T?

Probably for the same reason I give here:

http://www.peaktestosterone.com/Cialis_Long_Term.aspx

In that study they said the 5.5% increase in testosterone was not statistically significant ("no changes in T and f T serum levels were observed"), and they could only speculate on why estradiol decreased, saying there was "possible inhibition of aromatase activity during chronic exposure to tadalafil."
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 56, Ht: 5'10", Wt: 154 lbs
Protocol: 18 mg T cyptionate subQ qod, 250 IU hCG subQ qod, 6.25 mg DHEA orally bid, 7.5 mg preg. orally qd
5/2017 test results: TT: 800 ng/dL (348-1197), FT: 16 pg/mL (7.2-24), E2: 50 pg/mL sensitive (8.0-35.0), DHEA-S: 278 ug/dL (71.6-375.4)

Peak Testosterone Forum

Re: Why/How does Viagra raise Testosterone?
« Reply #3 on: January 08, 2018, 10:49:37 am »


BBkingbluesking122

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Re: Why/How does Viagra raise Testosterone?
« Reply #4 on: January 08, 2018, 11:57:54 am »
If you look at this study on the libido enhancing effects of Allium Tubersome (ATB) they compared it against Viagra. Only the highest doses of ATB come close to Viagras effect on T/FSH/DHT.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709831/


So how does V raise T?

You go over there.
Age: 20
% Body Fat: 9 %

PeakT

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Re: Why/How does Viagra raise Testosterone?
« Reply #5 on: January 09, 2018, 05:28:27 pm »


In that study they said the 5.5% increase in testosterone was not statistically significant ("no changes in T and f T serum levels were observed"), and they could only speculate on why estradiol decreased, saying there was "possible inhibition of aromatase activity during chronic exposure to tadalafil."

Good catch.  How about this one then?

http://onlinelibrary.wiley.com/doi/10.1111/and.12751/abstract

"At the end of 3 months, mean testosterone values and IIEF scores showed an improvement from baseline values (from 3.6 0.5 to 5.2 0.3, from 11.3 1.9 to 19 0.8 respectively). After the treatment, serum LH levels were decreased (from 5.6 0.6 to 4.6 0.5). There was significantly difference in terms of baseline testosterone and luteinising hormone values and IIEF scores (p < .05). Based on our findings, we recommend tadalafil 5 mg once daily in those men with erectile dysfunction especially low testosterone levels accompanied by metabolic syndrome."
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program.aspx
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Cataceous

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Re: Why/How does Viagra raise Testosterone?
« Reply #6 on: January 09, 2018, 07:46:51 pm »
...  How about this one then?

http://onlinelibrary.wiley.com/doi/10.1111/and.12751/abstract

"At the end of 3 months, mean testosterone values and IIEF scores showed an improvement from baseline values (from 3.6 0.5 to 5.2 0.3, from 11.3 1.9 to 19 0.8 respectively). After the treatment, serum LH levels were decreased (from 5.6 0.6 to 4.6 0.5). There was significantly difference in terms of baseline testosterone and luteinising hormone values and IIEF scores (p < .05). Based on our findings, we recommend tadalafil 5 mg once daily in those men with erectile dysfunction especially low testosterone levels accompanied by metabolic syndrome."

Yes, the 44% increase in testosterone is about the same as the result of the sildenafil study.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 56, Ht: 5'10", Wt: 154 lbs
Protocol: 18 mg T cyptionate subQ qod, 250 IU hCG subQ qod, 6.25 mg DHEA orally bid, 7.5 mg preg. orally qd
5/2017 test results: TT: 800 ng/dL (348-1197), FT: 16 pg/mL (7.2-24), E2: 50 pg/mL sensitive (8.0-35.0), DHEA-S: 278 ug/dL (71.6-375.4)

PeakT

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Re: Why/How does Viagra raise Testosterone?
« Reply #7 on: January 10, 2018, 04:58:43 am »
There is also a study out there that says intercourse can increase testosterone.  So, obviously Cialis and Viagra may work partially or fully, just by getting guys back in the game:

http://www.peaktestosterone.com/Sex.aspx
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program.aspx
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Cataceous

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Re: Why/How does Viagra raise Testosterone?
« Reply #8 on: January 10, 2018, 06:03:19 am »
There is also a study out there that says intercourse can increase testosterone.  So, obviously Cialis and Viagra may work partially or fully, just by getting guys back in the game:

http://www.peaktestosterone.com/Sex.aspx

They argued against this in the sidenafil study:

Quote
The decrease in LH also means that the increase in testosterone is not caused by the fact that the subjects probably had more sex during the trial.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 56, Ht: 5'10", Wt: 154 lbs
Protocol: 18 mg T cyptionate subQ qod, 250 IU hCG subQ qod, 6.25 mg DHEA orally bid, 7.5 mg preg. orally qd
5/2017 test results: TT: 800 ng/dL (348-1197), FT: 16 pg/mL (7.2-24), E2: 50 pg/mL sensitive (8.0-35.0), DHEA-S: 278 ug/dL (71.6-375.4)

PeakT

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Re: Why/How does Viagra raise Testosterone?
« Reply #9 on: January 11, 2018, 05:27:17 am »
There is also a study out there that says intercourse can increase testosterone.  So, obviously Cialis and Viagra may work partially or fully, just by getting guys back in the game:

http://www.peaktestosterone.com/Sex.aspx

They argued against this in the sidenafil study:

Quote
The decrease in LH also means that the increase in testosterone is not caused by the fact that the subjects probably had more sex during the trial.

Dang!  C'mon Cataceous, sometimes you don't want to read the fine print.   ;D

No, I'll modify those pages - might take me a bit - and put a caveat in there.

I guess I am a little skeptical of their skepticism.  There is a evidence that a) hanging around an attractive woman can raise testosterone and b) just the anticipation of competition as well as competition itself can increase testosterone in us guys.  So the idea that intercourse would results in a shorter term increase in testosterone would not surprise me a bit.  Of course, it's another thing to assume it would increase baseline levels I guess.
« Last Edit: January 11, 2018, 05:31:47 am by PeakT »
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program.aspx
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Cataceous

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Re: Why/How does Viagra raise Testosterone?
« Reply #10 on: January 11, 2018, 06:24:26 am »
...
I guess I am a little skeptical of their skepticism.  There is a evidence that a) hanging around an attractive woman can raise testosterone and b) just the anticipation of competition as well as competition itself can increase testosterone in us guys.  So the idea that intercourse would results in a shorter term increase in testosterone would not surprise me a bit.  Of course, it's another thing to assume it would increase baseline levels I guess.

I guess the question is whether these modes of raising testosterone work via more LH.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 56, Ht: 5'10", Wt: 154 lbs
Protocol: 18 mg T cyptionate subQ qod, 250 IU hCG subQ qod, 6.25 mg DHEA orally bid, 7.5 mg preg. orally qd
5/2017 test results: TT: 800 ng/dL (348-1197), FT: 16 pg/mL (7.2-24), E2: 50 pg/mL sensitive (8.0-35.0), DHEA-S: 278 ug/dL (71.6-375.4)

Peak Testosterone Forum

Re: Why/How does Viagra raise Testosterone?
« Reply #10 on: January 11, 2018, 06:24:26 am »