I'd thought I'd update this thread with some relevant information in case it helps any of you. I believe I mentioned in another thread that Dr Shippen recommends Rhein Consulting Labs for a 24 hr cortisol test. I'm not quite ready to use them yet but went ahead and got my ducks in a row. I got the primary care out of network referral. So far I've been getting these out of network referrals for other services that are out of network (physician visit, labwork, etc.) and paying them up front and them submitting them online through a claims system to my HMO. It turns out the test is $225 and I was told it also includes analysis of other metabolites related to cortisol. I was also told that urine & blood can provide some basis of comparison. So, for example, if I get DHEA-S tested via blood at LabCorp around the same time as cortisol at Rhein, it would be comparable enough to provide a good picture as to what's going on in my adrenal system. I don't know the science behind this, but this is what they told me. Thought this info might be a useful update to this thread.