Just when you thought it was safe to crawl out from under your bed, researchers are uncovering a whole new class of chemical monstrosities. Obesogon sounds like some sort of Sumo Superhero, but it's not: it's actually your worst metabolic nightmare.

Imagine this: a chemical that during the embryonic and/or developmental stages turns growing cells into fat cells. Can you say "chunky thighs" and "lard butt"?

Do such dark molecules actually exist? Yes, they do and they're called obesogons. Even worse, some of them are common, everyday chemicals for us modern, urban dwellers. Consider the widespread class of chemicals called organotins. Organotins are very common and are used in paints, fungicides - yes, on what you eat - PVC plastics, wood treatments, cosmetics and so on. Certain animals, such as shellfish and shrimp, accumulate organotins in their tissues as well. Researchers have found significant levels in various vertebrate tissues including human, so this is anything but theoretical. [1]

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The problem with organotins is that they induce adipogenesis. Adipocytes are fat cells and adipogenesis is a sterile, scientific way of saying "the birth of fat cells". The last thing any of us needs is new fat cells bursting into existence, but that's exactly what adipogenesis describes. Fat cells serve a purpose, of course, but they are the scourge of middle age guys and increase estrogen and cortisol, two of our biggest enemies. (Read this link on The Many Evils of Fat for more details.)

So is there any evidence that obesogons actually affect mammals? One study looked at just one of the organotins, tributyltin chloride (TBT), and found that it dramatically increased fat in mice and other laboratory animals as well. [2]

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These are very powerful chemicals and minute amounds can have a dramatic effect. Because of this, many endocrinological researchers believe that obesogons are actually partially responsible for the obesity epidemic that plagues modern societies. Again, the reason is that exposure to even trace amounts in one's early developmental stages can lead to extra fatty tissue on your body that stays with you throughout your life.

Yes, eating too much coupled with a sedentary lifestyle is undoubtedly the greatest factor for obesity. However, as it turns out, chemical exposure may also play a major role as well.

One leading obesogon researcher's advice? Eat organic and use stainless steel and glass cookware. [3] I would guess that the less shellfish, the better, as well. All of this is particularly important for sexually active women who could get pregnant as the developing embryo is likely at risk.

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REFERENCES:

1) Endocrinology, 2006, 147(6):S50-S55, "Environmental Obesogons: Organotins and Endocrine Disruption via Nuclear Receptor Signaling"

2) Molecular Endocrinology 20 (9): 2141-2155, "Endocrine-Disrupting Organotin Compounds Are Potent Inducers of Adipogenesis in Vertebrates"

3) http://www.physorg.com/news175194836.html