With a few notable exceptions such as Vitamin D and Magnesium, supplements have done poorly in studies on heart disease, cancer and other conditions. The medical profession is justified in its lack of enthusiasm as the miraculous claims and expectations have, for the most most part, turned out to be nothing but hype. There is, however, a notable exception: the brain. The brain is the most complex machine - nothing theological meant by that - in the universe and is a huge energy and biochemical hog. It requires huge inflows of vitamins, nutrients and benefits greatly from antioxidants and other phytoprotective foods.
Study after study have showed that your brain is at risk if you are low on many key nutrients. Here are some examples:
2) Journal of Neurology, Neurosurgery, and Psychiatry, 2009;80:722-729, "Association between 25-hydroxyvitamin D levels and cognitive performance in middle-aged and older European men"
3) Am J Epidem, 1999, 150(1):27-44
4) J of Nutr,Aug 1996,(126)8:1992-1999
5) Amer J of Clin Nutr,Sep 2005,82(3):627-635
6) Am J Med,2005;118:161 7; Psychosomatic Medicine,2006,68:547-554
7) Neurology,Mar 28 2000,54(6):1265-72
8) J Am Geriatr Soc,Jun 1997,45(6):718-24
9) http://www.medicalnewstoday.com/articles/61555.php Lancet, 2007 Jun 2, 369(9576):1876-82, "Efficacy of folic acid supplementation in stroke prevention: a meta-analysis."
10) Lancet, 2007 Jan 20, 369(9557):208-16, "Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial"