Peak Testosterone Forum

General Category => Testosterone, Hormones and General Men's Health => Topic started by: Arginine on October 25, 2016, 06:49:28 pm

Title: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 25, 2016, 06:49:28 pm
Hello all, started sustanon 250mg 1x week, after 3month I have  T: 900ng/dl (normal), E2: 80pmol/l (normal), progesterone 2nmo/l (normal). With thyroid everything ok, cortisol 419nmol/l (normal).  When I start TRT after mont few days libido was unbelievable high, but only few days, all other times very bad. What else I should to check?
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: PeakT on October 25, 2016, 06:58:55 pm
Hello all, started sustanon 250mg 1x week, after 3month I have  T: 900ng/dl (normal), E2: 80pmol/l (normal), progesterone 2nmo/l (normal). With thyroid everything ok, cortisol 419nmol/l (normal).  When I start TRT after mont few days libido was unbelievable high, but only few days, all other times very bad. What else I should to check?

If you did really good initially, one theory out there is that you may have too high of a dose.  You could try going lower.  Also, you want to pull your DHT, because sometimes on TRT, DHT isn't quite where you want it to be.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: electrify on October 25, 2016, 07:06:59 pm
Do you have the lab ranges and stuff?
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 25, 2016, 07:10:11 pm
Hello all, started sustanon 250mg 1x week, after 3month I have  T: 900ng/dl (normal), E2: 80pmol/l (normal), progesterone 2nmo/l (normal). With thyroid everything ok, cortisol 419nmol/l (normal).  When I start TRT after mont few days libido was unbelievable high, but only few days, all other times very bad. What else I should to check?

If you did really good initially, one theory out there is that you may have too high of a dose.  You could try going lower.  Also, you want to pull your DHT, because sometimes on TRT, DHT isn't quite where you want it to be.

My DHT I think is ok, because I have little bit acne and oily skin, my T is not so high that dose will be to big. Prolactin also always was in normal ranges. I think it can be something else, maybe DHEAS?
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 25, 2016, 07:13:23 pm
Do you have the lab ranges and stuff?

Ragnges: E2 is: 0-150pmol/l, T is: 200 - 1000ng/dl, cortisol: 118 - 618nmol/l, progesterone: 0,9-4nmol/l.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: PeakT on October 25, 2016, 09:41:28 pm
Hello all, started sustanon 250mg 1x week, after 3month I have  T: 900ng/dl (normal), E2: 80pmol/l (normal), progesterone 2nmo/l (normal). With thyroid everything ok, cortisol 419nmol/l (normal).  When I start TRT after mont few days libido was unbelievable high, but only few days, all other times very bad. What else I should to check?

If you did really good initially, one theory out there is that you may have too high of a dose.  You could try going lower.  Also, you want to pull your DHT, because sometimes on TRT, DHT isn't quite where you want it to be.

My DHT I think is ok, because I have little bit acne and oily skin, my T is not so high that dose will be to big. Prolactin also always was in normal ranges. I think it can be something else, maybe DHEAS?

DHEA-S sure.  Also, you really need a 4 point cortisol saliva test to test cortisol.  What did you have done?
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 26, 2016, 03:13:06 am
Hello all, started sustanon 250mg 1x week, after 3month I have  T: 900ng/dl (normal), E2: 80pmol/l (normal), progesterone 2nmo/l (normal). With thyroid everything ok, cortisol 419nmol/l (normal).  When I start TRT after mont few days libido was unbelievable high, but only few days, all other times very bad. What else I should to check?

If you did really good initially, one theory out there is that you may have too high of a dose.  You could try going lower.  Also, you want to pull your DHT, because sometimes on TRT, DHT isn't quite where you want it to be.

My DHT I think is ok, because I have little bit acne and oily skin, my T is not so high that dose will be to big. Prolactin also always was in normal ranges. I think it can be something else, maybe DHEAS?

DHEA-S sure.  Also, you really need a 4 point cortisol saliva test to test cortisol.  What did you have done?

I have done my morning cortisol test. How about dopamine, should I check this also? What you feel when your DHEAS is too low?
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: PeakT on October 26, 2016, 02:55:40 pm
Hello all, started sustanon 250mg 1x week, after 3month I have  T: 900ng/dl (normal), E2: 80pmol/l (normal), progesterone 2nmo/l (normal). With thyroid everything ok, cortisol 419nmol/l (normal).  When I start TRT after mont few days libido was unbelievable high, but only few days, all other times very bad. What else I should to check?

If you did really good initially, one theory out there is that you may have too high of a dose.  You could try going lower.  Also, you want to pull your DHT, because sometimes on TRT, DHT isn't quite where you want it to be.

My DHT I think is ok, because I have little bit acne and oily skin, my T is not so high that dose will be to big. Prolactin also always was in normal ranges. I think it can be something else, maybe DHEAS?

DHEA-S sure.  Also, you really need a 4 point cortisol saliva test to test cortisol.  What did you have done?

I have done my morning cortisol test. How about dopamine, should I check this also? What you feel when your DHEAS is too low?

I felt greatly increased anxiety.

A one point non salivary cortisol pull doesnt give you a complete picture, especially if you are having fatigue and mental fog.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 26, 2016, 04:03:59 pm
Hmm I feel anxiety.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 26, 2016, 04:05:51 pm
Also I was use arimidex, before TRT, and only one arimidex increase my libido, my erecton was strong, but it gets my heart problems, so I stop use it. I try aromasin, and letrozole, but this few AI's not increase my libido.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: PeakT on October 26, 2016, 08:14:58 pm
Also I was use arimidex, before TRT, and only one arimidex increase my libido, my erecton was strong, but it gets my heart problems, so I stop use it. I try aromasin, and letrozole, but this few AI's not increase my libido.
Hmmm.  Not sure that has to do with the AI involved necessarily...
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 28, 2016, 01:04:56 pm
Ok I do my labs again, test is High, E2 is normal low, DHEA is normal high... so WTF?!?!? Where is my libidio???
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Cataceous on October 28, 2016, 01:39:55 pm
This would contradict your positive experience with the AI, but if estradiol was measured via immunoassay rather than LC/MS/MS then there's a good chance the actual value is lower. This could potentially contribute to lack of libido. See here (http://www.renalandurologynews.com/hypogonadism/high-estradiol-boosts-libido-in-men-on-testosterone-therapy/article/335894/), for example.

Quote
Elevated serum estradiol is associated with increased libido in men receiving testosterone supplementation therapy (TST), according to researchers.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 28, 2016, 05:08:51 pm
Can it be nervous system problem? I feel tense, stress. I think my symphatetic nervous system is overactive, maybe is some supplements tu reduce it?
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: PeakT on October 29, 2016, 06:19:07 am
Ok I do my labs again, test is High, E2 is normal low, DHEA is normal high... so WTF?!?!? Where is my libidio???

Sorry, super low estradiol could lead to heart palpitations.  What I meant to say is that I don't know one would lower your estradiol that much more assuming you took the equivalent dosage.  But your doctor should have that down.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 29, 2016, 06:31:38 am
My e2 is 22pg/ml, it's not super low.. But I have dry hands and lips, maybe it's for me too low, but I don't take any AI for about one month.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: PeakT on October 29, 2016, 04:33:26 pm
My e2 is 22pg/ml, it's not super low.. But I have dry hands and lips, maybe it's for me too low, but I don't take any AI for about one month.

Iif  have high shbg, and sorry i didnt check, then that could knock down your free estradiol also.
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: Arginine on October 30, 2016, 02:46:19 pm
My shbg is low 18nmol/l
Title: Re: TRT: 12 week, completely no libido, low energy, bad memory, brain fog.
Post by: PeakT on October 30, 2016, 10:51:50 pm
My shbg is low 18nmol/l

Oh okay.  Have you pulled LH?  I don't believe I saw that?