Peak Testosterone Forum

General Category => Testosterone, Hormones and General Men's Health => Topic started by: PeakT on February 23, 2014, 04:48:03 pm

Title: Citrulline Time to Peak
Post by: PeakT on February 23, 2014, 04:48:03 pm
Some of you have asked me how long Citrulline takes to work.  Here is a study that shows it peaks arginine levels an hour or two after ingestion:

http://www.citrage.com/wp-content/uploads/Dose-ranging-effects-of-citrulline-administration-on-plasma-amino-acids-and.pdf

Notice that it says "Short-term CIT administration is safe and well-tolerated. CIT is a potent precursor of ARG. However,
at the highest doses, CIT accumulated in plasma while plasma ARG levels increased less than expected. This may be due to saturation of the renal conversion of CIT into ARG."

If you have kidney issues, remember that citrulline is apparently putting a slight load on them.  This is probably a reason to spread out small doses imo.
Title: Re: Citrulline Time to Peak
Post by: bmw on March 12, 2014, 12:28:57 am
That makes sense.  I'm going to get the test strips and find out when it is, but it is not instant.  I believe it takes at least an hour or longer, but I'm only measuring that on how I feel.  What I've found interesting, however, is that the effect does last a long time once it kicks in, similar to beets which max out for 12 hours (according to the Nitric Oxide Solution). 

Dosage with this stuff, I've found is almost unbearable for me at 3g.  I'm now just going a little below the spoon to avoid any heaping dose, and I can now handle close to 3g per day, but it took me several days to get there.  Also, do not take this stuff after 6pm or so, or you won't sleep well.  At least that is how it affected me. 

Side note - The Chinese say never eat watermelon at night, it will keep you up.  Watermelon seeds are highly diuretic, I learned that the hard way :)

Title: Re: Citrulline Time to Peak
Post by: EH on March 12, 2014, 01:38:50 am
That makes sense.  I'm going to get the test strips and find out when it is, but it is not instant.  I believe it takes at least an hour or longer, but I'm only measuring that on how I feel.  What I've found interesting, however, is that the effect does last a long time once it kicks in, similar to beets which max out for 12 hours (according to the Nitric Oxide Solution). 

Dosage with this stuff, I've found is almost unbearable for me at 3g.  I'm now just going a little below the spoon to avoid any heaping dose, and I can now handle close to 3g per day, but it took me several days to get there.  Also, do not take this stuff after 6pm or so, or you won't sleep well.  At least that is how it affected me. 

Side note - The Chinese say never eat watermelon at night, it will keep you up.  Watermelon seeds are highly diuretic, I learned that the hard way :)

Watermelon is one of the foods that contains the highest amount of citrulline.
Title: Re: Citrulline Time to Peak
Post by: PeakT on March 12, 2014, 06:36:22 pm

Watermelon is one of the foods that contains the highest amount of citrulline.

Mostly in the rind from what I've read...
Title: Re: Citrulline Time to Peak
Post by: EH on March 12, 2014, 09:36:26 pm

Watermelon is one of the foods that contains the highest amount of citrulline.

Mostly in the rind from what I've read...

A USDA study reported in the March 2007 issue of "Nutrition" tested the effects of watermelon juice in amounts of 1 or 2 g per day. The study found that arginine concentrations increased by 12 percent at the lower dose and 22 percent at the 2 g dose. Fasting citrulline levels did not rise.

then in the same article...

a study by the Meyer Children's Hospital in the 2005 "Journal of Inherited Metabolic Disease" reported. Researchers gave healthy volunteers large amounts of watermelon and then tested their citrulline and arginine levels. All developed very high citrulline levels and, to a lesser extent, elevated arginine.

so who knows..

If you don't like watermelon seeds, you can eat the rind, as it contains the most citrulline. If gnawing on the rind doesn't appeal to you either, just eat the flesh, which also supplies plenty of citrulline. The yellow and orange varieties of watermelon contain more citrulline than the red, if you're looking for maximum levels.

i have my doubts about some of these Livestrong articles though.  Regardless, watermelon is on the menu this Summer!
http://www.livestrong.com/article/475380-are-watermelon-seeds-rich-in-citrulline/ (http://www.livestrong.com/article/475380-are-watermelon-seeds-rich-in-citrulline/)
Title: Re: Citrulline Time to Peak
Post by: PeakT on March 12, 2014, 11:09:57 pm
If you go crazy, watch out for the salicylates, of which watermelon is high in.  (These can block Vitamin K and gave my six year old - or so my theory goes - a noseblood one time.)
Title: Re: Citrulline Time to Peak
Post by: phatphish on March 13, 2014, 11:55:06 pm
Beware of Citrulline if you get migraines. It is a powerful vasodilator. Gave me headaches at a 1/4 teaspoon.
Title: Re: Citrulline Time to Peak
Post by: PeakT on March 14, 2014, 03:53:15 am
Beware of Citrulline if you get migraines. It is a powerful vasodilator. Gave me headaches at a 1/4 teaspoon.

Great warning phatphish and I added it here:

http://www.peaktestosterone.com/citrulline_benefits