Testosterone, Hormones and General Men's Health / Re: How do you know if you need Iodine? What form, brand and dose?« on: December 08, 2017, 09:29:36 pm »
... there is enough evidence that it provides benefit, and the risks are low, that it at least deserves more credence than the quackaroo meanderings of the commercial interests behind Pauling therapy.
I stand by the analogy, but am open to persuasion. Are there controlled studies demonstrating that doses of 12.5 mg and higher produce better outcomes than more reasonable amounts, like 600 micrograms and less? Argument from authority is no better here than in the Pauling situation.
Fair enough, Cat. Thanks for being open minded.
More food for thought. You'll notice that many studies conclude that increasing iodine consumption causes hypothyroidism as evidenced by rising levels of TSH. Case closed: Iodine is bad, right? This is unfortunate, and stems from an incomplete understanding of the role of TSH. As we know, high levels of TSH are considered to be an indicator of underactive thyroid. Clinically, an underactive thyroid can only be diagnosed by direct measurement of actual thyroid hormones. T3, T4, and the like. However, TSH has a second, less well known function, and that is to regulate the Sodium/Iodide Symporter, also known as NIS. In the presence of available iodine, TSH is secreted to activate the NIS to transport the iodine where it needs to go. The thyroid gland is not stimulated; T3 and T4 are unaffected, and the effect can last for up to six months. There is no clinical hypothyroidism, only increased TSH.
By ruling out studies that conclude iodine induces hypothyroidism based simply or solely on TSH measurement, the universe of negative studies shrinks considerably.