Recent Posts

1

Testosterone, Hormones and General Men's Health / Re: Does Testosterone and Thyroid levels interact?

« Last post by Cataceous on December 05, 2021, 12:00:32 pm »

...
It is by a company who I think only sells to pharmacies. Ortho-Molecular. And the product is called “adaptNall”. Not exactly sure if that is the proper spelling.
...

Adapten-All — "This unique blend of nutrients, herbs and adaptogens supports normal adrenal function during occasional stress and fatigue."


https://www.orthomolecularproducts.com/product/adapten-all

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Testosterone, Hormones and General Men's Health / Re: Does Testosterone and Thyroid levels interact?

« Last post by Flyingfool on December 05, 2021, 01:30:34 am »

Cujet,

My daughter has low cortisol. I’m fact her waking cortisol is reversed. Cortisol is suppose to rise pretty sick cola out 30 minutes after waking in the morning. Hers DECREASES pretty significantly. With repeated testing.

She takes an over the counter supplement that really has helped her. Every time she has tried to wean herself off or stop she has problems. Adds it back in and she feels well.

It is by a company who I think only sells to pharmacies. Ortho-Molecular. And the product is called “adaptNall”. Not exactly sure if that is the proper spelling.

Just thought I would mention it. FAR better than the side effects of Prednisone. Maybe if you can find it may be worth a try.

Also been reading and my wife has recently been Rx low dose Naltrexone. Supposed to be anti inflammatory and used to reduce autoimmune issues and antibodies and many other things. Some similar to prednisone. So another thing to look into. However not sure if there is any implication to getting pilot medical. I believe you said you are a pilot so you would have to look into this before taking it.

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Testosterone, Hormones and General Men's Health / Re: TRT is THE worst decision I've ever made

« Last post by Cataceous on November 25, 2021, 02:52:51 am »

It does seem paradoxical, but illustrates that some property or properties of exogenous testosterone make it more suppressive of the HPTA—the hypothalamus in particular—than endogenously produced testosterone. It seems likely the magnitude and variation of serum testosterone have something to do with it.

I've explored this area a little, trying to see if a low enough dose of exogenous testosterone would lessen the need for enclomiphene. But so far the experiments have not worked well enough to allow any firm conclusions.

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Testosterone, Hormones and General Men's Health / Re: How long after stopping Cypionate do your levels drop to prior to TRT levels?

« Last post by Cataceous on November 24, 2021, 12:05:07 pm »

The hope is that testosterone levels continue to increase even after two months. Levels may bottom out around two to four weeks after stopping TRT, with the exogenous testosterone out of your system, and your HPTA in the process of starting up. The restart of natural production isn't necessarily complete after two months. But there's no harm in seeing where you stand at that time.

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Testosterone, Hormones and General Men's Health / Re: TRT is THE worst decision I've ever made

« Last post by 53chevy on November 24, 2021, 08:28:57 am »

Here's something I'm struggling with. I just read a study of low T guys taking enclomiphene and it raised their T to a mean of 600 and their LH and FSH were above normal. It did this in 45 days or less. So if normal or high T levels keeps kisspeptin, gnrh or LH and FSH suppressed then I don't understand that study at all. According to this study seems to me nothing is needed except enclomiphene.

What I'm going to do just for experiment sake is do nothing but enclomiphene for a couple weeks and then go get some labs done to see where T, LH and FSH is.

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Testosterone, Hormones and General Men's Health / Re: TRT is THE worst decision I've ever made

« Last post by 53chevy on November 24, 2021, 08:24:13 am »

I don't know exactly. I took it for about 8 months and it's possibly the only supplement that has ever had any effect on me. I lost about 15 lbs and felt great on it but a few weeks after I quit taking it my world came crashing down.

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Testosterone, Hormones and General Men's Health / Re: TRT is THE worst decision I've ever made

« Last post by hello73 on November 24, 2021, 02:56:16 am »

I develop low T due to dhea use. I get on trt and feel great for three months then all of the sudden that all goes away but it's only coincidence that it happened at the same time I went on trt?? Seriously?? Wowee.

I may have missed it sorry but how did you develop low T issues taking DHEA?

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Testosterone, Hormones and General Men's Health / Re: How long after stopping Cypionate do your levels drop to prior to TRT levels?

« Last post by hello73 on November 24, 2021, 02:52:38 am »

Thanks. I understand 3 months off cypionate is a good time to retest but can't I test on day 60 let's say?
 Off cypionate I suspect my level is where I was prior to trt for now but I can at least see where I am now so long as I realise it can drop even more 3 months and beyond.

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Testosterone, Hormones and General Men's Health / Re: TRT is THE worst decision I've ever made

« Last post by Cataceous on November 20, 2021, 08:57:56 pm »

You have it right. Interestingly, while testosterone is indirectly suppressive—through estradiol—at both the hypothalamus and pituitary, it is also directly suppressive at the hypothalamus. This is why even androgens that don't aromatize can cause some degree of HPTA suppression. It also explains why SERMs do not work with TRT: kisspeptin production is blocked, which in turn halts GnRH production. By restoring GnRH and using enclomiphene I can in principle activate all the downstream hormones in spite of TRT. Kisspeptin is just added for completeness, as there's the possibility of harm from its attenuation in the hypothalamus, even though there are other production sites. It is possible that kisspeptin alone would work, and that using it with exogenous GnRH is creating redundant endogenous GnRH. But I can't easily measure what's happening, so I continue to take both to preserve the good subjective results.

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Testosterone, Hormones and General Men's Health / Re: TRT is THE worst decision I've ever made

« Last post by 53chevy on November 20, 2021, 07:12:29 am »

Took some time off from experimenting because I've been too busy to be all depressed or messed up due to hormones being out of whack but I'm back at it. If you'll recall I was on selegiline a few months ago. I think I was on it about 6 weeks and didn't see any real improvement, or so I thought. It did seem to make me piss more often which goes along with my dopamine/sodium excretion theory but what I didn't notice was that my asthma had disappeared while on selegiline. I didn't even notice until it came back with a vengeance about 2 weeks after I got off selegiline. This further makes me believe that low dopamine is at least one issue I'm having because low dopamine can cause asthma. Well, I wanted to give wellbutrin another try and see if I could work thru the depression it causes me so I started back on it a couple months ago. I was on it for about 6 weeks when I finally said enough, I can't handle the depression so I quit that. I went back on the selegiline about 4 weeks ago mostly to get rid of the asthma and for the last week there has been no asthma. It does seem to give me terrible heartburn tho so I guess for now I need to pick either heartburn or asthma. I think I'll deal with the heartburn for now.

Been reading up a little on Cat's regimen. I got some enclomiphene coming, should be here tomorrow. I have no clue if it's legit or not so I guess I'll have to get bloodwork after I've been on it for a bit to see if it's legit. I have some questions for Cat. I'm just now studying on your regimen so my knowledge on it is quite small. Why are you taking kisspeptin and gnrh with the enclomiphene? I now understand about the negative feedback loop and having to use serms to block the estrogen receptors so if you're blocking those receptors then why do you need kisspeptin and gnrh? Does a normal or high level of T play into the feedback and shutdown or lower gnrh output? Also, why use both kisspeptin and gnrh? Doesn't kisspeptin control gnrh? Seems like using one or the other would suffice.