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Optimal estradiol is whatever works best for you. Otherwise all we have is that estradiol peaksóon averageóin young males, and the average value for the peak is just under 30 pg/mL. If I'm remembering right, the standard deviation is something like 6 pg/mL.
So this has happened to me a few times now. Today I was driving and hadn't eaten anything and all of a sudden I started salivating and it tasted sweet. It doesn't ever last for a long time (maybe an hour or two) so I am not very concerned but I am curious. Has anyone ever experienced this or know what might be causing it?

Any medicine changes/dose changes recently for you?

Interesting.  You been out in the heat or humidity more (if it is warmer where you are at possibly)?  Sometimes, I notice that sunlight exposure can make me feel like that if I've not been outside much and I go outside in the bright sun especially if it is warmer/hot outside. 

It sounds a lot like what stimulants do and possibly even low cortisol or too much dopamine/norepinephrine/hyperthyroidism/etc. but just running ideas by you.  It may be much simpler than those things, but even things like stress/pain are worth considering. 

No changes in anything really, same 'ol shit different day. Although, lately I have been really fucking tired/no energy and my apatite hasn't been all that good.
It's not hot here, been raining all fucking spring and everything is flooded. I don't know, doesn't seem like it's a real threat. I'll mention it to the doctor when I see him.

Let us know how it goes if you'd like! 
Testosterone, Hormones and General Men's Health / Re: Daily Injection results
« Last post by instantk on May 24, 2019, 06:55:16 pm »
Is there an optimal level of estadiol sensitive? I seem to do best around 25-30 with my free t at around 350pg ml
Testosterone, Hormones and General Men's Health / Re: Daily Injection results
« Last post by Cataceous on May 24, 2019, 05:41:58 pm »
Whats the suggested tested for estrogen? I never knew to test free estrogen levels

This is a messy subject. The free estradiol test appears to have value, but it's been quite expensive in the past. It's getting better, but $90 still isn't cheap. You can calculate free estradiol pretty accurately provided you have accurate numbers for total estradiol and SHBG. Getting an accurate reading for total estradiol isn't as easy as it sounds. Mass spectrometry-based tests are capable of providing very accurate values. But these tests are tricky and easy to mess up. Experience has shown that many of these results are completely wrong. On the other hand, immunoassays are easy to perform and very repeatable, but these tests frequently give falsely-elevated values because they detect some other molecules in addition to estradiol.
Testosterone, Hormones and General Men's Health / Re: Daily Injection results
« Last post by instantk on May 24, 2019, 05:13:31 pm »
I just watched neil rouzier presentation on estrogen and its benefits.

Whats the suggested tested for estrogen? I never knew to test free estrogen levels
Testosterone, Hormones and General Men's Health / Re: Donating blood
« Last post by HRT Guru on May 24, 2019, 02:37:14 pm »
Seem like a rather normal thing that CAN happen, make sure you eat both before, and after donating, well hydrated (water). Take a look at how often you can do a power red, I think it was twice the regular 56 day limit???
Let me address a couple of your questions:

Regarding measuring venous leak:  that can be accomplished with a penile ultrasound at a urologist's office.  On my post I put "venous leak" in quotes since I have not had the test and have not been formally diagnosed with that condition.  However, I certain suffered from the primary symptom: losing an erection quickly.  That has been greatly improved.  If you look on the main Peak T web page, one of the primary causes of this condition is LOW T.  When the cells at the base of the penis are starved of T, they can weaken/wither causing the mechanism that traps blood in the penis to malfunction.  There are other causes of course: hardening of the artery walls etc.

You should experiment with various NO boosting supplements including the ones you mention.  It will vary by person, but they can greatly boost the effectiveness of Cialis/Viagra.  Of course strong T levels do that as well, since T/E regulates the NO production in the penis to a great extent.

Here are some other tips from the Website:

good to hear you actually gotten better. Iím actually starting SSRIís right now tho, because i truly tried for several years naturally and im at the point that my depression and anxiety took over and i canít even think straight and feel like my mind is turned off. if by trying it for an amount of time i donít get better, i will stop taking it, but right now im not on trt and need something to clear my mind so i can make proper decisions. here where i live trt protocols are not that good (offering the typical once every two weeks) and well since i have mental stuff going on i decided to try this before going private for trt.
The links that CR provided has some posts that mentioned that these two supplements (in addition to exercise and weight loss) can help men for I think NO or at least to achieve some of the efects of Cialis.

The are: 3g l-citrulline and 1mg Doxazosin daily. and possibly ginseng (dosage???)

What or how do these work?  Are there any known side effects of these supplements?
Testosterone, Hormones and General Men's Health / Donating blood
« Last post by Pennywise09 on May 24, 2019, 09:15:47 am »
Iíve donated blood a couple of times already to help keep my red blood cells intact after my Endo recommended it being on TRT. Has anyone done a power red donation? Iím doing that for my first time today. In the past when Iíve donated a pint I would be light headed for 24-48 hours if I do strenuous activities. Do you get the same way with a power red donation? Itís through the Red Cross.
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