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21
Testosterone, Hormones and General Men's Health / Re: New Labs -- Thoughts?
« Last post by bkb333 on February 22, 2019, 12:52:59 pm »
How can LIBIDO be good on SHBG Level of 114 Nmol and an Estradiol of 50. I am confused how that's even possible Brother.  But long as it is for you, that's all that matters man. Good to hear.

I was curious about that, too. My libido is better now (6/10) than it was pre-TRT (0/10), though SHBG has changed to 114 from 110.
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Testosterone, Hormones and General Men's Health / Re: New Labs -- Thoughts?
« Last post by DanMac on February 22, 2019, 12:29:51 pm »
How can LIBIDO be good on SHBG Level of 114 Nmol and an Estradiol of 50. I am confused how that's even possible Brother.  But long as it is for you, that's all that matters man. Good to hear.
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Testosterone, Hormones and General Men's Health / New Labs -- Thoughts?
« Last post by bkb333 on February 22, 2019, 11:03:20 am »
Hi everyone,

I just received updated bloodwork from one month into TRT. My protocol is: 2 clicks T-cream (200 mg/ml) ED applied trans-scrotally, 300 IU hCG 2X/week, and 25 mg Ibutamoren ED. Prior to beginning TRT, I was taking an AI (with the hCG and Ibutamoren), but I am longer doing so.

Here are the numbers, with comparisons to their previous counterparts:
Total T: increased from 1989 to 2338 (Ref 250-1100)
Free T: increased from 192.9 to 215.1 (Ref 35-155)
SHBG: increased from 110 to 114 (Ref 15.5-55.9)
 - Keep in mind that the previous total was recorded while I was taking an AI (.25 Anastrozole 3X/week).
Estradiol: decreased from 51 to 50 (Ref <29)
Cholesterol: increased from 189 to 200 (Ref <200)
LDL: increased from 124 to 136 (Ref <100)
HDL: decreased from 51 to 49 (Ref 40-60)
DHEA-S: increased from 270 (in Oct. 18) to 1009 (Ref 139-475)
I have been supplementing with 100 mg 2x/week.
IGF-1: decreased from 288 (in Oct. 18) to 193 (Ref 63-373)
 - During this time, I experimented with reducing Ibutamoren from 25 mg/ED to 25 mg/EOD to see if I really needed this peptide, which probably explains the drop.
HGB: increased from 15.1 to 15.5 (Ref 14-18)
HCT: increased from 44 to 45.7 (Ref 42-52)

Overall, I feel amazing -- way better than before TRT! I have noticed marked improvements in libido (from 0 to 6) and quality of life (from 7 to 9). I am surprised, though, to see that SHBG not only didn't drop, but in fact went up. My TT and FT, of course, continue to be quite high as a result. I should note that at the very start of my hormonal optimization journey (May 2018), my SHBG was 180.

I should note that am taking DHEA, 100mg 2X/week, and took a dose shortly before this test. I plan to lower this, likely to 25mg/day or EOD.

Should I be concerned about anything on here? I would love to hear your thoughts!
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your welcome.

Some authors suggest to have ferritin around 20-30, others around 50. All say to keep it under above the limit (your lab says 30) and under 100.  Also in the hospital where I went in hematologist ward most of doctors say to keep it under 100.  So I assume all values between 20-30-70 (not a big gap) could be fine, indeed if hematocrit and red blood cells are high you don't need to worry about it. If you have low iron I believe the first clear sing is low red blood cells, hemoglobin and hematocrit.

This guy wrote a book only on iron & ferritin, there are a lot of interesting articles on his blog:


http://roguehealthandfitness.com/high-iron-leads-to-low-testosterone/

http://roguehealthandfitness.com/iron-levels/

http://roguehealthandfitness.com/blood-donors-live-longer/

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Why do you want to increase your ferritin?

Ferritin is not your iron, it is just a deposit in your body, and it is better to keep it low since high ferritin is linked to a lot of diseases.

TRT and Testosterone both decrease ferritin since Testosterone promotes erytrhropoies. So body needs iron to take iron from stores to make new red blood cells. You have an iron deficiency  when your iron blood level (not ferritin) and you reed blood cells are too low. If your hemoglobin red blood cells are enough iron is fine.

Donating blood is good for the body since it reduces iron stores (ferritin) and lot of diseases risks. So keep continue to donate blood, you also help other people.

For high iron ask to a doctor.
Thank you for your post.
So would you say I was healther here?
I thought ferritin played a major role in thyroid function.
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Why do you want to increase your ferritin?

Ferritin is not your iron, it is just a deposit in your body, and it is better to keep it low since high ferritin is linked to a lot of diseases.

TRT and Testosterone both decrease ferritin since Testosterone promotes erytrhropoies. So body needs iron to take iron from stores to make new red blood cells. You have an iron deficiency  when your iron blood level (not ferritin) and you reed blood cells are too low. If your hemoglobin red blood cells are enough iron is fine.

Donating blood is good for the body since it reduces iron stores (ferritin) and lot of diseases risks. So keep continue to donate blood, you also help other people.

For high iron ask to a doctor.
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I have always had problems keeping my ferritin up since I started TRT.
This is the first time my iron has been this high.
I am taking no supplements I just eat a lot of red meat.



I would like your thoughts on the high iron and if you think I should donate a pint.
I have not donated in over a year. On a side note I live at alitude and my HCT runs 50.3 right now
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- Cancers cells need sugar all the time to survive and to grow, they can't use ketones while healthy cells can easily go on ketos (seems also they prefer ketones than sugar) ketones are very good for brain health. Sugar don't mean only sugar from ice cream but all sugar, even from rice, pasta, whole grain and cereals. etc.
- Higher blood sugar is associated with worse cancer prognosis, and high cancer risk (if you don't have it) you don't need a 180 blood sugar level, just few sugar points like from 70 to 90 can increase the risk.
- Ketosis is also associated with less cells damages due to free radicals, it means less aging. Sugar promotes aging trough many mechanisms (free radicals, inflammation, glycation) that are linked with cancer. Starches food also increase insulin, insulin promotes Insulin-like growth factor 1 (IGF-1) hormone that an anabolic hormone. All these mechanims are linked with cancer risk, many disease and they help cancer to growth.
- A lot of nutritionists suggest to eat whole grain, rice, pasta and avoid "sugar". Those things have the same effect on your body since after you have eaten a whole grain bread it is transformed in sugar (and fat) by your body. Many people don't know that white bread has a higher glycemic index than glucose, and that whole grain bread has approx the same glycemic index of white bread.
- I started ketotis just to try I would never came back to "sugar diet". I do a lot of sport every day. I can lift heavy and gain muscles easy. I don't think carbs are so important for gaining muscles, energy or sport performances. I have more energy without them. I'm 6 foot for 188 lbs. In November I was 169 lbs. I do not take any drugs or T. So 21 pounds of muscles in 3 months without carbs.
- People who still live in ketosis (some tribes from remote zones of africa or jungle) don't have all the medical issues rich countries have. They don't wash they teeth but they don't have cavities, They teeth are perfect without braces, they don't have high blood pressure, cancer, diabetes etc.... I know directly about a lot of teenagers, young adults and even kids to had cancer (and many other diseases). I think it is clear our diet lifestyle are different from right ones. But I didn't know anyone personally who tried keto with a cancer. diagnosis.
- I personally love keto state since it gives you a relaxed and calm mood. You have a lot of energy and and focus. Things you can't have if you run on  carbs.

After these statements are reported many cases of spontaneous cancer remissions due to many things. Sometime just without doing nothing, it may be the simple placebo effect.

For sure if I had that I would stop to eat every can of starches food immediately.  Even my ice cream cheat once in a while.
 
But is the same old story a lot of people are ill (not only with cancer) but they still eat a lot of junk food, smoke, don't do any sport and have a bad lifestyle....  They prefer to die instead of doing right things.
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I use exactly this technique and have noticed no problems with efficacy.


I presume that you have blood tests showing that your E2 has remained in a similar range as you would have expected?
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I have no data specifically that you ask.

However if cancer feeds on sugar, it would seem reasonable that reducing sugar would help “starve” the cancer cells. So elimination of added sugar and minimizing carbs that easily convert to sugar would make sense.

But, the body still converts the fat into glucose. Which is sugar. So there seems to be no way around sugar being available for all cells, including cancer cells.

Elimination of added sugar is simply an overall good thing for your health. Whether keto diet specifically is “the” answer is I believe still debatable.

As far as losing weigh. My mom has recently gone keto. And she cut all the bad stuff oit. She lost a few pounds and then Nothing.  Turns out she needed more water and more fat. When she ADDED fat and more water she began immediately to lose weight. Interesting that ADDING calories actually resulted in LOSING weight.
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