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It looks like I'm going to go with tamoxifen. I don't want to waste time and money with a possible fake enclomiphene. I don't have the luxury of having a doctor that will even listen much less want to try things outside the box so I'm stuck with doctoring myself and finding the meds online.
Compared to tamoxifen, enclomiphene is better for HPTA stimulation and also may be safer with respect to side effects. I've seen those claims of fakery. It's unfortunate. I find it tenuous to rely on at most two pharmaceutical-grade suppliers of enclomiphene.

There are other SERMs, such as toremifene and raloxifene. But is seems as though they are less popular for this application.
Is there a reason for enclomiphene over other serms? It seems enclomiphene is faked a lot with these resesrch peptide places.
Testosterone, Hormones and General Men's Health / Re: I'm back.
« Last post by Cataceous on April 02, 2021, 02:08:56 am »
I use Defy myself and frequently recommend them, but I do find myself diverging from them philosophically on some of these dosing issues. I think that if guys can't feel good on physiological doses then higher doses are at best partly compensating for other problems—such as the disruption of upstream hormones—and at worst introducing a variety of side effects. With physiological doses of testosterone an aromatase inhibitor shouldn't usually be needed. And I don't understand the use of one before estrogen levels are even known. I'll concede that use of hCG can significantly increase estradiol for many men. I had this problem and in the end never felt like I could get things right, with or without an AI. That's why I eventually abandoned hCG in favor of a complex method of restoring the upstream hormones.

Admittedly there is bias involved when I rely on my experiences and those of guys on the forums. These may be over-representing the frequency at which troubles are encountered under TRT; the happy guys aren't going to be here complaining. But I continue to think that for best health overall we want to be mimicking the hormone levels of average healthy young men, and not the extreme outliers.
Testosterone, Hormones and General Men's Health / Re: I'm back.
« Last post by Cronos on April 01, 2021, 08:54:32 pm »
I agree with you cataceous. But I'm not really sure what to do... I don't want to lower the dose without Defy approval but my follow up is still a ways away. Plus I really do feel fantastic apart from two days out of the week.
Testosterone, Hormones and General Men's Health / Re: I'm back.
« Last post by Cataceous on April 01, 2021, 08:44:15 pm »
Not to belabor the point, but I suspect the large testosterone dose is contributing to your difficulties. The average young guy is predicted to have peak testosterone reach 1,300+ ng/dL on this protocol, double the typical natural daily peak value.
Testosterone, Hormones and General Men's Health / Re: I'm back.
« Last post by Cronos on April 01, 2021, 07:48:50 pm »
Like clock work. Today is the day after one of my injection and I feel horrible. Anxiety lack of motivation, mood disturbances, irritable. So inject sunday/wednesday. Take my HCG and Anastrozole monday/Thursday.. Am I chasing Estradiol or something here. By far the worse days are the days after my injections. Take my HCG and Anastrozole and about 8 hours after that I start to feel better.
Certainly everyone is different. Nonetheless, in terms of dosing it's like the difference between a guy being on TRT at 75 mg TC per week or blasting at 500 mg per week. The effects are not going to be the same. It'll be interesting to see how long it takes you to have gonadotropin production. The results from Royal Medical Center suggest that at these high doses enclomiphene isn't needed. But it's questionable that the experience compares well to what would be expected with physiological levels.
It took 9 days after my first dose on trt to feel human again, and this was coming out of a MAJOR depression. It took 3 or 4 days to get morning wood like a teenager. Somewhere around the two month mark I had already dropped 25 lbs with no diet or exercise so you can see why I call that time line hogwash. It has never taken me more than a few days to a couple of weeks to feel the effects of anything. Besides that were not talking about trt and using a slow ester, we're talking about kisspeptin raising LH and FSH and going by that study the amount LH and FSH is raised is quite dose dependent up to a certain dose. I just don't see the need in dragging it out any further than necessary with a minute dose, it's just not logical.
I guess Popeye was right.
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