« Last post by seppuku on March 24, 2021, 11:53:17 am »
Seppuku your suggestion got me thinking. It never occurred to me that Clomid/enclomiphene could have a dampening effect on estrogen receptors! So I checked some old notes/labs I made Sept.2018 – Aug 2020. By mid-2019 and into June 2020 my libido was not great but acceptable. My protocol was still a work in progress at that time but it was generally around 12.5mg Clomid and DIM 200mg four to six times a month. Unfortunately I got too complacent and took only one lab for the year - December 2019. This lab was TT 820 pg/mL, Free T 84 pg/mL, estradiol <20 (?), SHBG 83nmol/L, LH 4.8 miU/ml etc. Unremarkable, almost normal. Then in July 2020 I unfortunately tweaked the protocol a little and my libido declined. My 08/07/20 lab was TT 1283.1 pg/mL, Free T 98.5 pg/mL, estradiol 43 pg/ml, SHBG 85 nmol/L, LH 5.3 mlU/ml. Hormones are truly a balancing act. Maybe someday... Interesting idea about neurotransmitters, I’ll speak with my doctor concerning replacing my Wellbutrin with selegiiline. Thank you.
No problem, and good luck! I've been reading other peoples progress and experiences for years - most people seem to get the fat loss / muscle building effects etc from increased testosterone, but it's always libido that causes problems. It's such a tricky one and probably depends on many factors (hormones but also stress, sleep, diet etc etc). And it would seem that generally, very low e2 levels are worse than very high ones, but there's always a sweet spot. Regarding clomid, for me, and more (or less) than 12.5mg three times a week, and i just don't feel right.