Quantcast

Author Topic: Healthy T level co-existing with elevated E2?  (Read 3389 times)

Anon123

  • Guest
Healthy T level co-existing with elevated E2?
« on: March 14, 2013, 11:12:07 am »
Is it possible for a healthy level of T to co-exist with an elevated Estradiol/E2 level?

The reason I ask is because I suspect that, due to varicocele, I might have elevated E2 as I think I may have gynocomastia in one breast.

Does elevated E2 cause gynocomastia? Can you have healthy T level but still get gyno due to elevated E2?
« Last Edit: August 09, 2018, 12:58:59 pm by Cataceous »

JackAndy

  • Hero Member
  • *****
  • Posts: 1233
    • View Profile
Re: Healthy T level co-existing with elevated E2?
« Reply #1 on: March 14, 2013, 11:21:22 am »
No, yes, yes.

When your estrogen is elevated far enough, you will get symptoms. Gynocomastia is one of them.
Age:29
5'11" 190 lbs
150mg Test-E/week

Peak Testosterone Forum

Re: Healthy T level co-existing with elevated E2?
« Reply #1 on: March 14, 2013, 11:21:22 am »


PeakT

  • Administrator
  • Hero Member
  • *****
  • Posts: 38446
    • View Profile
    • Peak Testosterone
Re: Healthy T level co-existing with elevated E2?
« Reply #2 on: March 14, 2013, 03:39:15 pm »
Is it possible for a healthy level of T to co-exist with an elevated Estradiol/E2 level?

The reason I ask is because I suspect that, due to varicocele, I might have elevated E2 as I think I may have gynocomastia in one breast.

Does elevated E2 cause gynocomastia? Can you have healthy T level but still get gyno due to elevated E2?

Many men have decent testosterone and elevated estradiol.  However, I think where JackAndy was headed was this:  as you put on weight, your estradiol tends to rise AND your testosterone begins to fall in a man with a fairly normal functioning HPA and testes.  So you'll tend to see lower T with higher E2 in this case of being overweight.  Again, if you can afford it, it's always good to get tested and find out where you stand imo.

As you start to go hypogonadal things change, of course, but that's not what your talking about here.

Yes, elevated E2 is a big factor in gyno but not the only factor.  Notice that this study says that it is the ratio of T/E2 that seems to matter:

http://journals.lww.com/nuclearmed/Abstract/1998/11000/Ga_67_Uptake_by_the_Male_Breast_Under_Digitalis.16

But gynocomastia is actually pretty complex and not understood all the way.  Look at all the factors they have found that can influence it including prolactin, hyperthyroidism and various medications.  It's not just steroid hormone plasma levels that count but also tissue receptors in the breast (if you'll pardon the expression) tissue of men.

Here is some more info if you haven't seen it:

http://www.peaktestosterone.com/Gynocomastia_Prevention
« Last Edit: August 09, 2018, 12:59:09 pm by Cataceous »
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Anon123

  • Guest
Re: Healthy T level co-existing with elevated E2?
« Reply #3 on: March 15, 2013, 05:39:18 pm »
So today the right breast pain that began about a week ago has got a little worse. I wondered if maybe something I was doing differently was the cause. I did a little research. For the last few weeks I've been using, every other day approx., a Magnesium oil spray which also contains Glucosamine and Winter Green and Menthol oils.

I found this article which suggests some of these oils may act as endocrine disruptors: http://www.nih.gov/news/pr/jan2007/niehs-31.htm

So I'm going to stop using it and see what happens.
« Last Edit: August 09, 2018, 12:58:53 pm by Cataceous »

Peak Testosterone Forum

Re: Healthy T level co-existing with elevated E2?
« Reply #3 on: March 15, 2013, 05:39:18 pm »


PeakT

  • Administrator
  • Hero Member
  • *****
  • Posts: 38446
    • View Profile
    • Peak Testosterone
Re: Healthy T level co-existing with elevated E2?
« Reply #4 on: March 15, 2013, 06:06:59 pm »
So today the right breast pain that began about a week ago has got a little worse. I wondered if maybe something I was doing differently was the cause. I did a little research. For the last few weeks I've been using, every other day approx., a Magnesium oil spray which also contains Glucosamine and Winter Green and Menthol oils.

I found this article which suggests some of these oils may act as endocrine disruptors: http://www.nih.gov/news/pr/jan2007/niehs-31.htm

So I'm going to stop using it and see what happens.

Let us know...
« Last Edit: August 09, 2018, 12:59:16 pm by Cataceous »
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Peak Testosterone Forum

Re: Healthy T level co-existing with elevated E2?
« Reply #4 on: March 15, 2013, 06:06:59 pm »