How Quickly Does Estradiol Rise on HRT?

[TheWife]

his e2 was at 23 before the injection but we do want to make sure it stays below about 30. How quickly does it go up? I guess what i mean by that is... we should see some improvement before the E2 rises  right am I correct in assuming it wont rise fast enough to cancel out the benefits before we even see them?

I don't know when Doc is planning on checking it again but he is planning on checking.

[PeakT]

his e2 was at 23 before the injection but we do want to make sure it stays below about 30. How quickly does it go up? I guess what i mean by that is... we should see some improvement before the E2 rises  right am I correct in assuming it wont rise fast enough to cancel out the benefits before we even see them?

I don't know when Doc is planning on checking it again but he is planning on checking.

It goes up right away.  Your body is converting it on the fly via the aromatase enzyme. 

It's quite common to have the experience that JackAndy described where your brain feels like it's being rewired on the spot.  Testosterone is VERY important to the (male) brain and science is just now understanding that.  Neurotransmitters are being boosted.  Cell growth is being initiated.  It's amazing.  Now why not all guys feel that - I don't know.  But even men who don't get the initial "rush" should notice nice improvements in mood, ability to concentrate, memory and so on after a few months.

I do want to emphasize again, though, that testosterone is not a silver bullet.  You've got to complement it with diet, exercise, sleep and stress management.  Most men need their arteries cleared out and cleared out badly or at least put on damage control:

http://www.peaktestosterone.com/Clear_Your_Arteries

http://www.peaktestosterone.com/Med  (Mediterranean Diet)

http://www.peaktestosterone.com/Sexercise (Exercise and a Man's Sex Life)

[TheWife]

thanks PeakT
The doctor did say he is going to monitor the E2 but we don't have any tests scheduled yet. I think he is planning to test everything again when we go in to get the testopel.

It will probably be 2 - 3 weeks. Is that too long to wait?

[PeakT]

thanks PeakT
The doctor did say he is going to monitor the E2 but we don't have any tests scheduled yet. I think he is planning to test everything again when we go in to get the testopel.

It will probably be 2 - 3 weeks. Is that too long to wait?

Nope.  Very common and the right thing to do.  Sounds like you've got a good doc in that regard...

[Ken]

I can give you what I just went through regarding E2.  Before injections my E2 was 16.2.  After 1 month of injections I was retested.  My total T shot up from 310 to 460, but my E2 shot up even higher percentage wise to 34.0.  I'm fairly lean and in pretty good shape (13% body fat) and I was pretty surprised at this E2 value.  I had thought it wouldn't shoot up that much since my body fat was pretty decent.  Oops.  Wrong assumption.  As Peak has said in many of his posts, "some guys are just high converters"

Anyway, because of the new quickly rising E2, my doc put me on a pretty small dosage of Arimidex to block the T to E2 conversion process.  I will be retested in about 3 more weeks and we will see how it is working.

Here's the interesting thing though: Even though my E2 did shoot up to 34 (still within normal range by the way) I still have been experiencing a pretty profound improvement in the areas expected to improve as a result of TRT.  I have had none of the symptoms or signs of E2 being too high and it doesn't seem to be diminishing my gains from the T therapy at all.  Energy, mood, libido, and performance in the gym are all way up!

Just as some guys are "high converters" I suspect that some guys might have different levels of sensitivity to E2 levels as well.  I'm sure Peak can correct me if I'm mistaken on this.

Anyway, don't get too worried about the E2 levels just yet.  Wait until the follow up blood work and then adjust things from there as recommended by your doctor.

Good Luck.