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Author Topic: The Wise and Witty Robert Sapolsky: Erections, the ANS, and Erectile Dysfunction  (Read 5631 times)

Kierkegaard

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https://youtu.be/D9H9qTdserM?t=43m13s -- until 48:15

Quick overview:

-The autonomic nervous system: parasympathetic and sympathetic, and their importance in relation to orgasm. 

-Psychogenic or physiogenic ED; 60% of men who come to doctors for ED are psychogenic, meaning they aren't physical.

-Penile pressure cuff thingy to help determine nocturnal erections (which happen during REM sleep); using stamps is a much better way of measuring.

The whole presentation is outstanding and relates to the title of his equally outstanding book on stress and its many effects on the body, Why Zebras Don't Get Ulcers.  Also good info directly before the timestamp on testosterone and how you need a "thimbleful" and a "few sperm" for fertility.  I recommend the whole lecture. 
"The same thing that makes you live can kill you in the end." -- Neil Young

March 2014: Dx low T (158ng/dl)
September 2015: Dx hypothyroidism, other adrenal hypofunction
2016: chronic fatigue, unspecified

Depression and anxiety guide: http://www.peaktestosterone.com/Help_Anxiety_Depression

PeakT

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https://youtu.be/D9H9qTdserM?t=43m13s -- until 48:15

Quick overview:

-The autonomic nervous system: parasympathetic and sympathetic, and their importance in relation to orgasm. 

-Psychogenic or physiogenic ED; 60% of men who come to doctors for ED are psychogenic, meaning they aren't physical.

-Penile pressure cuff thingy to help determine nocturnal erections (which happen during REM sleep); using stamps is a much better way of measuring.

The whole presentation is outstanding and relates to the title of his equally outstanding book on stress and its many effects on the body, Why Zebras Don't Get Ulcers.  Also good info directly before the timestamp on testosterone and how you need a "thimbleful" and a "few sperm" for fertility.  I recommend the whole lecture.

That makes a heck of a lot of sense, especially with younger guys!  I have thought many times about how incredibly stressful we have had life for our physiology.  We have turned everything into a big competition.  We are competing with our neighbors, globally, etc. and we have to raise our kids to compete the same way.  And we have turned the bedroom often into the same kind of high pressure environment for many different reasons I think - not everyone - but I think many guys feel that way.  A lot of the posts on here I think reflect that.

What was said about morning erections makes a LOT of sense with regards to heart disease as well.  Look at the study here where Cialis only restored morning erections in those without much plaque:

http://www.peaktestosterone.com/Loss_Morning_Erections_Arterial_Plaque

Now I do have my usually patronly warning here:  pay attention to what is said about the morning erections.  As you age, if you have erectile dysfunction and are not getting morrning erections, you REALLY need to pay attention to that.  Don't freak out.  Don't panic.  But several studies have shown that most men in Western society build up plaque in their arteries and the plaque first effect not the heart, but the smaller arteries in the groin area - the pudendal (that supplies blood to the penis) and the penile arteries themselves.  So erectile dysfunction can be a very important warning sign of early plaque buildup and impending heart disease.  It gives you the same chance to turn your life around that low SHBG does for the early prediabetic folks.  I talk about these facts here:

http://www.peaktestosterone.com/Erectile_Dysfunction_Arteries
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

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electrify

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I still feel like the whole stress- nocturnal erections thing is hard to say whether its 'psychogenic' or 'physiogenic'.

Cause isn't it possible to have say lower Testosterone levels but have nocturnal wood and still suffer from anxiety-depression symptoms which then go on to inhibit erections?

Or even non-T related things like allopregnanolone, other neurosteroids, neurotransmitters, etc?

Ie--the things that are difficult to still measure but within the realm of physiological dysfunction.

Theres a ton of people suffering from weed induced DP/DR problems for example and then they have ED, etc but maybe still have morning wood. The thing is--is this physiogenic due to the HPA axis hormonal systems or is this psychogenic? (DP/DR as im sure you know is related to HPA axis alterations).

Seems like weed induced DP/DR cases are mostly referred out to psychologists though even if the patient had no mental health issues prior to the physiologically induced panic attack which caused it.

ALso--when he refers to hippocampal atrophy and says its "not reversible" then how do people recover from depression/anxiety/etc? As far as I understand, antidepressant treatments whether pharmacological or psychological or lifestyle act to increase BDNF in some ways and then lead to neurogenesis right?

Additionally, Sapolsky seems to go more toward the theory high glucocorticoids in depression/anxiety. I wonder why Dr.M and other docs often say that they rarely see high cortisol in depression and that its often low. Who is right?
« Last Edit: September 02, 2017, 06:20:06 pm by electrify »
Age:24

PeakT

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I still feel like the whole stress- nocturnal erections thing is hard to say whether its 'psychogenic' or 'physiogenic'.

Cause isn't it possible to have say lower Testosterone levels but have nocturnal wood and still suffer from anxiety-depression symptoms which then go on to inhibit erections?

Or even non-T related things like allopregnanolone, other neurosteroids, neurotransmitters, etc?

Ie--the things that are difficult to still measure but within the realm of physiological dysfunction.

Theres a ton of people suffering from weed induced DP/DR problems for example and then they have ED, etc but maybe still have morning wood. The thing is--is this physiogenic due to the HPA axis hormonal systems or is this psychogenic? (DP/DR as im sure you know is related to HPA axis alterations).

Seems like weed induced DP/DR cases are mostly referred out to psychologists though even if the patient had no mental health issues prior to the physiologically induced panic attack which caused it.

ALso--when he refers to hippocampal atrophy and says its "not reversible" then how do people recover from depression/anxiety/etc? As far as I understand, antidepressant treatments whether pharmacological or psychological or lifestyle act to increase BDNF in some ways and then lead to neurogenesis right?

Additionally, Sapolsky seems to go more toward the theory high glucocorticoids in depression/anxiety. I wonder why Dr.M and other docs often say that they rarely see high cortisol in depression and that its often low. Who is right?

Lots of guys with pretty low testosterone but still get morning erections.  On the other hand. it raises insulin, increases rhe risk of venous leak and lowers key neurotransmitters as you go lower.  So, if you go low enough, eventually it will bite you.
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Peak Testosterone Forum


electrify

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I still feel like the whole stress- nocturnal erections thing is hard to say whether its 'psychogenic' or 'physiogenic'.

Cause isn't it possible to have say lower Testosterone levels but have nocturnal wood and still suffer from anxiety-depression symptoms which then go on to inhibit erections?

Or even non-T related things like allopregnanolone, other neurosteroids, neurotransmitters, etc?

Ie--the things that are difficult to still measure but within the realm of physiological dysfunction.

Theres a ton of people suffering from weed induced DP/DR problems for example and then they have ED, etc but maybe still have morning wood. The thing is--is this physiogenic due to the HPA axis hormonal systems or is this psychogenic? (DP/DR as im sure you know is related to HPA axis alterations).

Seems like weed induced DP/DR cases are mostly referred out to psychologists though even if the patient had no mental health issues prior to the physiologically induced panic attack which caused it.

ALso--when he refers to hippocampal atrophy and says its "not reversible" then how do people recover from depression/anxiety/etc? As far as I understand, antidepressant treatments whether pharmacological or psychological or lifestyle act to increase BDNF in some ways and then lead to neurogenesis right?

Additionally, Sapolsky seems to go more toward the theory high glucocorticoids in depression/anxiety. I wonder why Dr.M and other docs often say that they rarely see high cortisol in depression and that its often low. Who is right?

Lots of guys with pretty low testosterone but still get morning erections.  On the other hand. it raises insulin, increases rhe risk of venous leak and lowers key neurotransmitters as you go lower.  So, if you go low enough, eventually it will bite you.

This is why im on TRT/HCG/Preg. I haven't been on it continuously technically but I've been on/off enough times to see that my body is resilient enough to recover to at least its previous levels and quickly too. And I think concurrent HCG use plays a role here. So I'm on this indefinitely until everything gets sorted out for a while. I don't see it as a big doom 'treatment for life' thing. Plus, subQ injections are easy enough
Age:24

PeakT

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This is why im on TRT/HCG/Preg. I haven't been on it continuously technically but I've been on/off enough times to see that my body is resilient enough to recover to at least its previous levels and quickly too. And I think concurrent HCG use plays a role here. So I'm on this indefinitely until everything gets sorted out for a while. I don't see it as a big doom 'treatment for life' thing. Plus, subQ injections are easy enough

I agree, but I'd with they'd run a study or two to prove it.
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

PeakT

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Bump...
« Last Edit: September 11, 2017, 01:39:00 am by PeakT »
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

electrify

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Well the other thing that is hardly talked about on here is that neurotransmitters can also impact morning wood. Its not just a Testosterone thing.

Some people who have PSSD or PFS have normal T levels but still suffer from lack of morning wood.
Age:24

PeakT

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Great thread, but I am destickying it.  Anyone have anything to add?
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Peak Testosterone Forum