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Author Topic: Sudden loss of libido and ED while on TRT  (Read 4349 times)

Zooka15

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Re: Sudden loss of libido and ED while on TRT
« Reply #15 on: November 06, 2017, 01:48:50 pm »
How long have you been on bp meds? After about a year my libido and erection went to hell. Quit my bp med and all returned.

golfboy307

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Re: Sudden loss of libido and ED while on TRT
« Reply #16 on: November 06, 2017, 03:26:31 pm »
I have been on them for about 2-3 years.  I tried everything to lower it "naturally" (diet and even more exercise), but I was stuck at 140/90.  I had some level of ED/venous leak before starting on them.  They really didn't seem to affect the erections much either way.  Given the regime I am on with my Body Logic doctor, my BP is running below 120/80 quite frequently.  He wants me to phase the BP meds down/out if possible, but I haven't given that a shot just yet.

I appreciate the suggestion.  Zooka, we corresponded awhile ago.  How did you do on limiting E2?
Age 51, 5'10, 155 lbs
Cholesterol 162 (HDL 59, LDL 87, Trigs 88, LDL-P 850)
Fasting Glucose 65 (down from 97 pre TRT)
A1C:  5.0 (down from 5.7 per TRT)
Homocysteine:  12.4 > 11.0 > 10.2 > 8.9 using B vitamin therapy.  MTHFR positive 

BP  120/78 (using improved diet and 10 mg Lisinopril ACE Inhibitor)  145/90 prior to meds.

Current protocol:  60 mg Test Cyp IM every 5 days.  No AI.
2/15/17 labs:  Total T (peak day): 1169 (250 - 1100 ng/dl).  Free T 198 pg/ML (46-225).  Sensitive E2: 40 High.  Previously 32. PSA 0.2  Hemocrit 44.2. SHBG: 32
9/15/18 labs:  Total T (trough day):  598 (250 -1100 ng/dl)  Free T 73.9 (46-225) Sensitive E2: 21  Hemocrit 43.7  SHBG 34
2/20/19 labs:  Total T (mid point):  776 (250 -1100 ng/dl) Free T 115.6 (46 - 224 pg/ml) Sensitive E2 24 (<29), DHT 43 (16-79 ng), DHEA-s 244 (70-495 mcg/dl)


Supplements:  Multivitamin, plus additional B12, B6, C, D, K2, Red Yeast Rice, Magnesium, and Coq10  Evening:  Kyolic Garlic, 2mg Cialis, LEF Endothelial Protection

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Re: Sudden loss of libido and ED while on TRT
« Reply #16 on: November 06, 2017, 03:26:31 pm »


golfboy307

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Re: Sudden loss of libido and ED while on TRT
« Reply #17 on: November 16, 2017, 07:55:19 am »
Thought I would give a brief positive update:

Based on comments and suggestions I cut my dose from 70mg to 60mg e5d for the last couple of injections.  I have seen a nice return of nocturnal/morning erections and libido over the last 10 days or so.  Also sleeping much better.  I didn't order labs, but suspect I was going too high on both total T and E2.  (I was around 40 back in May on the sensitive test, and around 1100 peak day using the 70mg).

It seems so counter intuitive, but as repeated on this site often, more is definitely NOT better.   Hope the trend continues.
Age 51, 5'10, 155 lbs
Cholesterol 162 (HDL 59, LDL 87, Trigs 88, LDL-P 850)
Fasting Glucose 65 (down from 97 pre TRT)
A1C:  5.0 (down from 5.7 per TRT)
Homocysteine:  12.4 > 11.0 > 10.2 > 8.9 using B vitamin therapy.  MTHFR positive 

BP  120/78 (using improved diet and 10 mg Lisinopril ACE Inhibitor)  145/90 prior to meds.

Current protocol:  60 mg Test Cyp IM every 5 days.  No AI.
2/15/17 labs:  Total T (peak day): 1169 (250 - 1100 ng/dl).  Free T 198 pg/ML (46-225).  Sensitive E2: 40 High.  Previously 32. PSA 0.2  Hemocrit 44.2. SHBG: 32
9/15/18 labs:  Total T (trough day):  598 (250 -1100 ng/dl)  Free T 73.9 (46-225) Sensitive E2: 21  Hemocrit 43.7  SHBG 34
2/20/19 labs:  Total T (mid point):  776 (250 -1100 ng/dl) Free T 115.6 (46 - 224 pg/ml) Sensitive E2 24 (<29), DHT 43 (16-79 ng), DHEA-s 244 (70-495 mcg/dl)


Supplements:  Multivitamin, plus additional B12, B6, C, D, K2, Red Yeast Rice, Magnesium, and Coq10  Evening:  Kyolic Garlic, 2mg Cialis, LEF Endothelial Protection

PeakT

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Re: Sudden loss of libido and ED while on TRT
« Reply #18 on: November 16, 2017, 10:24:31 am »
Thought I would give a brief positive update:

Based on comments and suggestions I cut my dose from 70mg to 60mg e5d for the last couple of injections.  I have seen a nice return of nocturnal/morning erections and libido over the last 10 days or so.  Also sleeping much better.  I didn't order labs, but suspect I was going too high on both total T and E2.  (I was around 40 back in May on the sensitive test, and around 1100 peak day using the 70mg).

It seems so counter intuitive, but as repeated on this site often, more is definitely NOT better.   Hope the trend continues.

Let us know if the benefits keep going. 
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program.aspx
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

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Re: Sudden loss of libido and ED while on TRT
« Reply #18 on: November 16, 2017, 10:24:31 am »


chrisL

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Re: Sudden loss of libido and ED while on TRT
« Reply #19 on: November 16, 2017, 10:32:33 am »
Thought I would give a brief positive update:

Based on comments and suggestions I cut my dose from 70mg to 60mg e5d for the last couple of injections.  I have seen a nice return of nocturnal/morning erections and libido over the last 10 days or so.  Also sleeping much better.  I didn't order labs, but suspect I was going too high on both total T and E2.  (I was around 40 back in May on the sensitive test, and around 1100 peak day using the 70mg).

It seems so counter intuitive, but as repeated on this site often, more is definitely NOT better.   Hope the trend continues.

it might be the drop of E2 that followed the drop of T that did the trick..

golfboy307

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Re: Sudden loss of libido and ED while on TRT
« Reply #20 on: November 16, 2017, 03:13:54 pm »
That is exactly what I am thinking...
Age 51, 5'10, 155 lbs
Cholesterol 162 (HDL 59, LDL 87, Trigs 88, LDL-P 850)
Fasting Glucose 65 (down from 97 pre TRT)
A1C:  5.0 (down from 5.7 per TRT)
Homocysteine:  12.4 > 11.0 > 10.2 > 8.9 using B vitamin therapy.  MTHFR positive 

BP  120/78 (using improved diet and 10 mg Lisinopril ACE Inhibitor)  145/90 prior to meds.

Current protocol:  60 mg Test Cyp IM every 5 days.  No AI.
2/15/17 labs:  Total T (peak day): 1169 (250 - 1100 ng/dl).  Free T 198 pg/ML (46-225).  Sensitive E2: 40 High.  Previously 32. PSA 0.2  Hemocrit 44.2. SHBG: 32
9/15/18 labs:  Total T (trough day):  598 (250 -1100 ng/dl)  Free T 73.9 (46-225) Sensitive E2: 21  Hemocrit 43.7  SHBG 34
2/20/19 labs:  Total T (mid point):  776 (250 -1100 ng/dl) Free T 115.6 (46 - 224 pg/ml) Sensitive E2 24 (<29), DHT 43 (16-79 ng), DHEA-s 244 (70-495 mcg/dl)


Supplements:  Multivitamin, plus additional B12, B6, C, D, K2, Red Yeast Rice, Magnesium, and Coq10  Evening:  Kyolic Garlic, 2mg Cialis, LEF Endothelial Protection

Nocturne

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Re: Sudden loss of libido and ED while on TRT
« Reply #21 on: November 16, 2017, 07:43:36 pm »
Congrats, Golf!  How is the morning anxiety going?  I think the E2 was likely your problem as well - my T rarely goes above 500 and I still had a hard time keeping my eyes off of a twenty something today at the protein shake place I go to (and she wasnít even particularly hot; a little pudgy, even, but in the right way).  My point is that a man doesnít really need T in the 1000s to have a decent libido, so it was almost certainly something other than lack of T that was causing you problems.

If you still have anxiety in the mornings, might I suggest GABA?  Still working well for me, although mornings are still the WORST time for me to gain/maintain erections, most likely due to the slight anxiety I get even with the GABA).
43 years old
5'7", was 220 pounds when trouble started, now down to 165
Trouble began with abrupt ED Early May '15
Initial T level 130
Started Clomid in hopes of rebooting system June '15
Currently taking 25 mg eod and .25 mg Arimidex every 4 days
T level 480 or so at last reading
ED in check with 2.5 mg Cialis eod and supplements:
POM juice, L-Cit, Pycnogenol

Morning anxiety currently in check with GABA taken every night

Biggest current worry is heart health:
Aortic stenosis (very mild for now)
CAC score 156(!) at age 42
Lp(a) is a shockingly bad 390 nmol/L -- TRIPLE the "extremely high risk" level!
Homozygous for the bad "G" variant of SNP rs10455872, which increases Lp(a) as well as odds for aortic stenosis and coronary artery lesions. 
I think I know what trashed my heart...

40 mg Crestor and baby aspirin every day
CoQ-10, Vitamin K2, and Kyolic Aged Garlic Extract every day too
Walking 10,000 steps a day

charliebizz

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Re: Sudden loss of libido and ED while on TRT
« Reply #22 on: November 17, 2017, 04:40:29 am »
This thread is really making me feel more positive about my trt Experiance. A few years ago I tried trt and it really made me feel worse and more of a rollercoaster ride. This time around (only one month in ) I donít feel as bad however I have yet to see any positives and it has brought out some anxiety and other small symptoms. However back a few years ago I was on between 80-100mg im once a week and my levels were around 700-800 near my next shot. Now Iím doing 100mg sub q m-w-f. Seeing the other thread about the difference between sub q dosing and Im. Im going to assume Iím on too much myself. And I also seem to be one of those guys who suffer from low e2.

Anyway just makes me feel better to know a little tweaking can go a long way. Back when I was on trt last time nobody hardly ever went down in dose. Itís nice to see these lower dose protocols working out

cujet

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Re: Sudden loss of libido and ED while on TRT
« Reply #23 on: November 17, 2017, 04:51:50 am »
I cycle using T, I discovered this help immensely when I ran out many years ago. As I find I have much the same situation, where I'm good for long periods of time, then trend down. A brief rest period of not using the T cream, say 4 to 10 days, seems to fix all. I just came off such a cycle, as I ran out of cream and stretched the last bit of it out, so my levels declined slowly. It was only about 3 days without, but a nice decline on my way there. A week after restarting, I'm back to fighting form.
55 years old
Autoimmune Hashimoto's, near zero natural T production
Cause: severe mononucleosis in my early 30's
Weight 200
Height 5' 10"
190mg NPthyroid (natural dessicated pigs thyroid)
Labs (Oct 2017) , my T=730, TSH 0.03, T3+T4 mid-range normal.
 
Currently not using T of any sort due to low cortisol

golfboy307

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Re: Sudden loss of libido and ED while on TRT
« Reply #24 on: November 17, 2017, 08:17:19 am »
Thanks Noc, yes, the morning anxiety and sleep issues disappeared quickly after I dropped my dosage.  I will keep GABA in mind. 

I had fairly high SHBG before I started this process, so the higher T levels helped me initially.  I think my maintenance dosage can be a bit lower now to keep the E2 under control. 

Yes, to the others, I am learning too that small changes in protocol can have big effects. 
Age 51, 5'10, 155 lbs
Cholesterol 162 (HDL 59, LDL 87, Trigs 88, LDL-P 850)
Fasting Glucose 65 (down from 97 pre TRT)
A1C:  5.0 (down from 5.7 per TRT)
Homocysteine:  12.4 > 11.0 > 10.2 > 8.9 using B vitamin therapy.  MTHFR positive 

BP  120/78 (using improved diet and 10 mg Lisinopril ACE Inhibitor)  145/90 prior to meds.

Current protocol:  60 mg Test Cyp IM every 5 days.  No AI.
2/15/17 labs:  Total T (peak day): 1169 (250 - 1100 ng/dl).  Free T 198 pg/ML (46-225).  Sensitive E2: 40 High.  Previously 32. PSA 0.2  Hemocrit 44.2. SHBG: 32
9/15/18 labs:  Total T (trough day):  598 (250 -1100 ng/dl)  Free T 73.9 (46-225) Sensitive E2: 21  Hemocrit 43.7  SHBG 34
2/20/19 labs:  Total T (mid point):  776 (250 -1100 ng/dl) Free T 115.6 (46 - 224 pg/ml) Sensitive E2 24 (<29), DHT 43 (16-79 ng), DHEA-s 244 (70-495 mcg/dl)


Supplements:  Multivitamin, plus additional B12, B6, C, D, K2, Red Yeast Rice, Magnesium, and Coq10  Evening:  Kyolic Garlic, 2mg Cialis, LEF Endothelial Protection

Forty2

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Re: Sudden loss of libido and ED while on TRT
« Reply #25 on: November 17, 2017, 03:15:24 pm »
I cycle using T, I discovered this help immensely when I ran out many years ago. As I find I have much the same situation, where I'm good for long periods of time, then trend down. A brief rest period of not using the T cream, say 4 to 10 days, seems to fix all. I just came off such a cycle, as I ran out of cream and stretched the last bit of it out, so my levels declined slowly. It was only about 3 days without, but a nice decline on my way there. A week after restarting, I'm back to fighting form.

cujet, how long do you use T cream before taking a 4-10 day break from it? Do you feel a drop in libido and energy when you're off the T cream for that long?

cujet

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Re: Sudden loss of libido and ED while on TRT
« Reply #26 on: November 18, 2017, 07:20:25 pm »

cujet, how long do you use T cream before taking a 4-10 day break from it? Do you feel a drop in libido and energy when you're off the T cream for that long?

Sometimes 6 months, sometimes 2-3 months. I go by feel, mostly by declining libido. Strangely enough, sometimes when I stop, libido goes sky high for a few days. Always after starting again, libido is amazing. I'm married and therefore, more than a little frustrated.
55 years old
Autoimmune Hashimoto's, near zero natural T production
Cause: severe mononucleosis in my early 30's
Weight 200
Height 5' 10"
190mg NPthyroid (natural dessicated pigs thyroid)
Labs (Oct 2017) , my T=730, TSH 0.03, T3+T4 mid-range normal.
 
Currently not using T of any sort due to low cortisol

Forty2

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Re: Sudden loss of libido and ED while on TRT
« Reply #27 on: November 19, 2017, 03:54:05 am »

cujet, how long do you use T cream before taking a 4-10 day break from it? Do you feel a drop in libido and energy when you're off the T cream for that long?

Sometimes 6 months, sometimes 2-3 months. I go by feel, mostly by declining libido. Strangely enough, sometimes when I stop, libido goes sky high for a few days. Always after starting again, libido is amazing. I'm married and therefore, more than a little frustrated.

How long have you been married for and how long did it take after you got married for your libido to decline? I can never see myself getting married, because whenever I'm with the same woman for more than several months, my libido declines from seeing the same body day in day out, no matter how beautiful she looks. My libido always goes high when I start a new relationship with another attractive woman, but after 6 months tops, I'm ready to switch to a new girlfriend to restart my libido again.

cujet

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Re: Sudden loss of libido and ED while on TRT
« Reply #28 on: November 19, 2017, 05:45:13 am »

How long have you been married for and how long did it take after you got married for your libido to decline? I can never see myself getting married, because whenever I'm with the same woman for more than several months, my libido declines from seeing the same body day in day out, no matter how beautiful she looks. My libido always goes high when I start a new relationship with another attractive woman, but after 6 months tops, I'm ready to switch to a new girlfriend to restart my libido again.

30 years. I see your point....
55 years old
Autoimmune Hashimoto's, near zero natural T production
Cause: severe mononucleosis in my early 30's
Weight 200
Height 5' 10"
190mg NPthyroid (natural dessicated pigs thyroid)
Labs (Oct 2017) , my T=730, TSH 0.03, T3+T4 mid-range normal.
 
Currently not using T of any sort due to low cortisol

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Re: Sudden loss of libido and ED while on TRT
« Reply #28 on: November 19, 2017, 05:45:13 am »