Writing for my husband. You all seem to know more about this than anyone. Forgive me if it’s a repeat but most posts I see about low E have to do with an AI.
35 years old, about 20 pounds overweight.
Started 50mg/day compounded T cream daily 5 weeks ago for decreased (like very little) libido, lack of motivation, difficulty losing weight, trouble with memory/focus.
He had monitored for about 6-8 months- trying natural ways to increase (supplements, working out, etc), total T stayed in low-mid 300.
Labs when starting cream:
Total T 330 (264-916)
Free T 9.75 (5-21)
FSH 3.5 (1.5-12.4)
LH 3.7 (1.7-8.6)
Estradiol 21 (7.6-42.6)
IGF 250 (83-233)
Vitamin D 36 (30-100)
After 5 weeks:
Total T 447 (264-916)
Free T 15.78 (5-21)
FSH 2.7 (1.5-12.4)
LH 3.2 (1.7-8.6)
Estradiol 5.5 (7.6-42.6)
IGF 246 (83-233)
Vitamin D 39 (30-100)
Thyroid function is good. TSH is optimal range (1.5), Free T4, and Free T3 are in the top quarter. Although reverse T3 is high. But I think that’s ok since T3 is top of normal.
The testosterone seems better but the Estradiol is SO much lower. There has been zero improvement in symptoms, he really hasn’t noticed anything at all, although I think libido May even be a bit worse. Diet has been good, working out, hasn’t lost a pound.
He is taking DIM, general vitamins/mineral supplements, and Vitamin D. Really needs to lose the few pounds due to borderline BP with heart defect.
Can DIM lower E this much? Any other thoughts or advice? Any thoughts on the elevated IGF (should we worry about Pit tumor? Dr said no because of LH/FSH)