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Author Topic: 200mg test cyp a week. Weak/soft muscle tissue after workout and no libido  (Read 642 times)

MustangGT31

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Hi fellas,

I have been doing a lot of reading on this forum and a lot of research so far on test cyp.
I've got to say, I'm really glad for this forum and the internet lol. You all are very knowledgeable, so I know I'm asking the right questions to the right people.

About 5 weeks ago I was prescribed 200 mg test cyp every 14 days. And like most of you have pointed out, that dosing is archaic and prone to issues. I went back to my doctor 2 weeks ago and got the dosage frequency increased to every 7 days. For the first week everything was fine, then I started to notice symptoms. They were worse than before I started TRT. On Monday I went to the gym, I lift heavy three days a week and do Judo twice a week. When I started lifting my warmup set I noticed I was weaker than the previous week. That injection was on 4th of July. When I was done my muscles were softer than usual (usually they are hard as a rock, even after lifting) and I felt like crap. Couldn't sleep that night and was still sore and soft. To complicate matters my erections have been ho hum and it takes me a while to fire one off. Admittedly, I took 1mg of anastrozole yesterday to try to elevate my symptoms. My thinking was that my issues were high E2. Last night I couldn't sleep worth a crap, I mean at all. And while my erections are back they don't last long and I can't fire any bullets. I'm at a loss, and the only thing I can think of doing is to split my injection up or to take the whole thing and .5 mg of anastrozole the day after. What are your guys' thoughts on those two options?

I cannot do bloodwork every week, as I am a cash patient and I do not have the money to fork out 78 dollars a week to figure out were my E2 is. Testosterone levels or a bit more expensive too. Right now, the only thing I can do is go by feel until my appointment in August.

P.S. the doc never gave me anastrozole and only did after I complained about symptoms.
Bloodwork before TRT:
Total testosterone 240
Free testosterone 68
SHBG 16
Estradiol under 20
Age 31

Cataceous

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Take a look at some of the threads on low SHBG. Yours is not outrageously low, but still well under the preferred mid-20s to mid-30s range. The implications are that you should be injecting at least twice a week—EOD better yet—to reduce hormonal fluctuations, and estradiol in particular. And it would be wise to start with a lower-than-average dose, something like 60-80 mg T cypionate in total each week.

It's preferable to be cautious with anastrozole use. One milligram is a huge dose. There's a lot of variation in sensitivity to the drug, so it can be easy to inadvertently crash estradiol. My weekly total is only 0.175 mg, for example. Ideally you would stabilize before adding an AI, as one is not always needed. Frequent injections and a lower total dose would give you a better chance. Testing is not something to be done weekly. You should allow four to eight weeks between protocol changes before retesting.

Consider TRT as a long-term project. Protocol changes and improvements take place over many months. Patience is important, though admittedly difficult to come by when things aren't going well.
« Last Edit: July 12, 2018, 06:00:06 am by Cataceous »
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 57, Ht: 5'10", Wt: 158 lbs
Protocol: 18 mg T enanthate subQ qod, 250 IU hCG subQ qod, 70 mcg anastrozole qod, 6.25 mg DHEA orally bid
7-12/2018 test results: TT: 800 ng/dL, E2: 31 pg/mL LC/MS-MS, DHEA-S: 264 ug/dL (49-344)—SHBG ~30 nmol/L

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Mindscape

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Your SHBG is low and your protocol is wrong for you, low SHBG guys need smaller multiple injection per week. Large infrequent injections in low SHBG men will drive estrogen production and low SHBG men can't tolerate even moderate estrogen levels, this is why you don't feel well and you'll never see libido on these large weekly injection protocols.

I'm have low SHBG and don't feel well unless injecting 16-20mg EOD.  It's clear this doctor doesn't know how to play this TRT game very well, it might be time for a true hormone specialists.

MustangGT31

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Take a look at some of the threads on low SHBG. Yours is not outrageously low, but still well under the preferred mid-20s to mid-30s range. The implications are that you should be injecting at least twice a week—EOD better yet—to reduce hormonal fluctuations, and estradiol in particular. And it would be wise to start with a lower-than-average dose, something like 60-80 mg T cypionate in total each week.

It's preferable to be cautious with anastrozole use. One milligram is a huge dose. There's a lot of variation in sensitivity to the drug, so it can be easy to inadvertently crash estradiol. My weekly total is only 0.175 mg, for example. Ideally you would stabilize before adding an AI, as one is not always needed. Frequent injections and a lower total dose would give you a better chance. Testing is not something to be done weekly. You should allow four to eight weeks between protocol changes before retesting.

Consider TRT as a long-term project. Protocol changes and improvements take place over many months. Patience is important, though admittedly difficult to come by when things aren't going well.

I liked your suggestion for sure about splitting up my dosage. I'll run it by my doc and see what she thinks. And you're right, I've only been on my current protocol for a couple weeks now. I've always been inpatient but with something as complex as hormones I need to realize that it's not going to be an overnight thing. I'll also talk with he about splitting up the anastrozole, so that when I inject I'm taking the right anastrozole to testosterone ratio.  Thank you again for your time.

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MustangGT31

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Your SHBG is low and your protocol is wrong for you, low SHBG guys need smaller multiple injection per week. Large infrequent injections in low SHBG men will drive estrogen production and low SHBG men can't tolerate even moderate estrogen levels, this is why you don't feel well and you'll never see libido on these large weekly injection protocols.

I'm have low SHBG and don't feel well unless injecting 16-20mg EOD.  It's clear this doctor doesn't know how to play this TRT game very well, it might be time for a true hormone specialists.

I certainly agree with you that EOD injections might be better for me. I am going to talk with her about adjusting my protocol a bit and will ask about dividing dosage accordingly.  Something has to give as I can't be horny and not get it up or likewise I can't be hard as a rock and not horny lol. I do think she's trying her best for sure, I'm not happy about no anti-E meds with 200mg, but I think that since doctors only spend a day at most on endocrinology in med school that it's not something that they no well right out of the gate. There might be better docs out there but I also feel like it's my job as a patient to report and document any changes in my body/symptoms so that my physician can make the proper adjustments. If, for some reason, I feel like she isnt taking my symptoms seriously then I'll go somewhere else. Thank you so much for your input.

MustangGT31

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So, I bit the bullet and paid for a sensitive estradiol and free/total T test today. I'll see what my blood look like then I'll post the results. I will say that after taking the 1mg of anastrozole, granted I wasn't able to sleep the night of, my muscle tissue is back to being as hard as a rock and I was able to perform well in the gym. We'll see what the results although. I really hope that it pans out as I don't have 86 dollars to do this all the time lol.

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