Only thing that seems to help my fatigue is increasing norepi and dopa. Increasing testosterone now after 5 years of Androgel in the past has recently only revved up my heart rate and made me more fatigued and anxiety-provoked. I'm pretty sure SSRI meds are just depleting my norepi and dopa and making me more tired and lethargic. That's why I'm slowly coming off them because I don't ever feel motivated on them and constantly tired, hungry, numb, unsatisfied, and having sex dysfunction. Yet, they do help my cortisol is what I suspect, yet you know how effing crazy docs are when it comes to acknowledging hormonal influences with meds. Most don't know a damn thing but I actually surprised the crap out of my psych doc when he was astonished I was correct that SSRI's are raising my prolactin and depleting testosterone.