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Author Topic: Triptorelin for Hpta restart?  (Read 628 times)

Steve78

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Triptorelin for Hpta restart?
« on: December 02, 2018, 08:44:25 am »
Reports of this working well.   Dr crisler had positive case reports.   But not much published about it.  Anyone try it or know more about triptorelin?

PakMan

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Re: Triptorelin for Hpta restart?
« Reply #1 on: December 02, 2018, 07:12:54 pm »
Reports of this working well.   Dr crisler had positive case reports.   But not much published about it.  Anyone try it or know more about triptorelin?

Wikipedia says it actually suppresses LH and testosterone and is used to chemically castrate sex offenders. Isn't that the opposite of HPTA restart?
Age: 46, HT: 5' 7'', WT: 75 kg

Jan 16 to Oct 16 - Test Enanthate (35mg 2x/week)
Oct 16 to Feb 17 - HCG (500iu 2x/Week)
Feb 17 - Test Propionate (25mg only 2 injections 4 days apart)
Aug 2017 onwards (Astaxanthin + other oils, supplements)
Dec 2017 Low dose TRT (25 mg twice a week)
Nothing from Jan 1, 2019

21/08/2017 8:10 PM
Total T = 271 ng/dl  (Range 160 - 726)
LH = 5.15 mIU/ml  (Range 0.8 - 7.6)

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Re: Triptorelin for Hpta restart?
« Reply #1 on: December 02, 2018, 07:12:54 pm »


Sean Mosher

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Re: Triptorelin for Hpta restart?
« Reply #2 on: December 03, 2018, 10:03:14 am »
I was under the understanding that Dr. Crisler initially had some promising results but then he stopped using it at all.
Not sure if it stopped working or what.......
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Cataceous

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Re: Triptorelin for Hpta restart?
« Reply #3 on: December 03, 2018, 10:07:33 am »
Here's an article explaining how low doses are used for a restart: http://www.peptidequestions.com/peptides/triptorelin-gnrh/

Quote
Triptorelin is so powerful that large doses around 4mg (4,000mcg), repeated once a month, is being used as a chemical form of castration. This dose is so intense on the pituitary, that it hyper-stimulates, resulting in castration-like levels of testosterone serum in the body. Much like HCG, dosing is delicate, and too much is not a good thing. We need to use Triptorelin as a restart, one-and-done, and not over-do things because it may have a much more opposite and negative effect.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 57, Ht: 5'10", Wt: 158 lbs
Protocol: 18 mg T enanthate subQ qod, 250 IU hCG subQ qod, 70 mcg anastrozole qod, 6.25 mg DHEA orally bid
7-12/2018 test results: TT: 800 ng/dL, E2: 31 pg/mL LC/MS-MS, DHEA-S: 264 ug/dL (49-344)—SHBG ~30 nmol/L

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Re: Triptorelin for Hpta restart?
« Reply #3 on: December 03, 2018, 10:07:33 am »


Steve78

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Re: Triptorelin for Hpta restart?
« Reply #4 on: December 03, 2018, 11:07:56 am »
Yes, I read 100 mcg one time is all that’s needed.

Problem is the stuff is impossible to find and I don’t trust those research chem sites...

charliebizz

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Re: Triptorelin for Hpta restart?
« Reply #5 on: December 12, 2018, 04:17:10 am »
I tried it two separate times with the doc. Did not do anything for me personally

PakMan

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Re: Triptorelin for Hpta restart?
« Reply #6 on: December 31, 2018, 10:30:50 pm »
Here's an article explaining how low doses are used for a restart: http://www.peptidequestions.com/peptides/triptorelin-gnrh/

Quote
Triptorelin is so powerful that large doses around 4mg (4,000mcg), repeated once a month, is being used as a chemical form of castration. This dose is so intense on the pituitary, that it hyper-stimulates, resulting in castration-like levels of testosterone serum in the body. Much like HCG, dosing is delicate, and too much is not a good thing. We need to use Triptorelin as a restart, one-and-done, and not over-do things because it may have a much more opposite and negative effect.

Does it have a half life for weeks/months or does one time stimulation keep the pituitary up working 24/7 for weeks?
What is its half life and can you take it subq?
Age: 46, HT: 5' 7'', WT: 75 kg

Jan 16 to Oct 16 - Test Enanthate (35mg 2x/week)
Oct 16 to Feb 17 - HCG (500iu 2x/Week)
Feb 17 - Test Propionate (25mg only 2 injections 4 days apart)
Aug 2017 onwards (Astaxanthin + other oils, supplements)
Dec 2017 Low dose TRT (25 mg twice a week)
Nothing from Jan 1, 2019

21/08/2017 8:10 PM
Total T = 271 ng/dl  (Range 160 - 726)
LH = 5.15 mIU/ml  (Range 0.8 - 7.6)

Steve78

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Re: Triptorelin for Hpta restart?
« Reply #7 on: January 01, 2019, 07:43:14 am »
Does dr saya ever write it?

Stuff is hard to get

Cataceous

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Re: Triptorelin for Hpta restart?
« Reply #8 on: January 01, 2019, 08:44:10 am »
...
Does it have a half life for weeks/months or does one time stimulation keep the pituitary up working 24/7 for weeks?
What is its half life and can you take it subq?

The idea with the restart is a one-time stimulation to kick-start the pituitary. This reference suggests the drug can be taken IM or subQ. Regarding half life it says:

Quote
The pharmacokinetics of triptorelin follows a 3 compartment model. The half lives are estimated to be 6 minutes, 45 minutes, and 3 hours respectively.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 57, Ht: 5'10", Wt: 158 lbs
Protocol: 18 mg T enanthate subQ qod, 250 IU hCG subQ qod, 70 mcg anastrozole qod, 6.25 mg DHEA orally bid
7-12/2018 test results: TT: 800 ng/dL, E2: 31 pg/mL LC/MS-MS, DHEA-S: 264 ug/dL (49-344)—SHBG ~30 nmol/L

PakMan

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Re: Triptorelin for Hpta restart?
« Reply #9 on: January 02, 2019, 01:05:25 am »
Does dr saya ever write it?

Stuff is hard to get

What about Luprorelin? It seems to be cheaper too?
Age: 46, HT: 5' 7'', WT: 75 kg

Jan 16 to Oct 16 - Test Enanthate (35mg 2x/week)
Oct 16 to Feb 17 - HCG (500iu 2x/Week)
Feb 17 - Test Propionate (25mg only 2 injections 4 days apart)
Aug 2017 onwards (Astaxanthin + other oils, supplements)
Dec 2017 Low dose TRT (25 mg twice a week)
Nothing from Jan 1, 2019

21/08/2017 8:10 PM
Total T = 271 ng/dl  (Range 160 - 726)
LH = 5.15 mIU/ml  (Range 0.8 - 7.6)

Steve78

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Re: Triptorelin for Hpta restart?
« Reply #10 on: January 03, 2019, 02:30:11 pm »
Here's an article explaining how low doses are used for a restart: http://www.peptidequestions.com/peptides/triptorelin-gnrh/

Quote
Triptorelin is so powerful that large doses around 4mg (4,000mcg), repeated once a month, is being used as a chemical form of castration. This dose is so intense on the pituitary, that it hyper-stimulates, resulting in castration-like levels of testosterone serum in the body. Much like HCG, dosing is delicate, and too much is not a good thing. We need to use Triptorelin as a restart, one-and-done, and not over-do things because it may have a much more opposite and negative effect.

Does it have a half life for weeks/months or does one time stimulation keep the pituitary up working 24/7 for weeks?
What is its half life and can you take it subq?

Seems like a good idea for a restart.  Wonder why it’s not used or you don’t hear much about it.   Hmmm

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Re: Triptorelin for Hpta restart?
« Reply #10 on: January 03, 2019, 02:30:11 pm »