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Author Topic: General Mens health question. Metformin if you don't have diabetes.  (Read 189 times)

HRD LVN

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I have been a Defy patient since 2016 and have really got my TRT protocol dialed in.
At the start of each year I try to look at other aspects of my genral health. 2017 it was thyroid.
2018 it was my natural GH and the use of peptides like Sermorelin and Ipamorelin.
Just so you guys know Defy sells Sermorelin and they are a forum sponsor.
I have not headed down the AAS or recreational T path.

So this year I am looking at insulin resistance basic blood sugars levels. I bought a blood gluecose monitor from amazon.
Its a FreeStyle unit. The review were good and it is very easy to use.
I have been testing my blood sugars for almost 6 months now in prep for my Defy consult in late Feb.  I test when I wake up 3-4 times a week.
I have tested 1 hour and 2 hours post breakfast. I have tested post lunch time after eating and fasting with no lunch. I have also tested just before bedtime.
Now most of this testing is because I am a data geek and I love working with excel.
Although I have gotten my A1C down from 6.4 in 2015 to 5.3 this year with diet exersize and Defy's consults my blood sugar numbers looks like crap to me.

Like clock work my morning test is 130 pretty much on the dot every morning. Google calls that dawn phenomenon.
3 hours later pre breakfast my reading ~99 and 1 hour post breakfast its 120 and 2 hours later it 100. 
My low outliers are min to high 80s  Random measurement after noon is in the 90's.
I even ran myself into what I would call a hypoglycemic episode at the gym and my number measured 80

So I am thinking about asking to try metformin. Anyone out there with some info on insulin resistance that is not diabetic?
Are there other test I might do pre-defy consult. I am just in the basic learn stage here and would appreciate your thoughts and ideas.
thanks

bkb333

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Re: General Mens health question. Metformin if you don't have diabetes.
« Reply #1 on: January 12, 2019, 08:21:03 am »
I'm very curious about this as well, having heard many tout the benefits of Metformin.
High SHBG guy
27 YO, 6'2", 172 lbs, 11.5% BF
50 mg T-cyp cream (daily), 25mg Ibutamoren (daily), 300 IU hCG (2x week)

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Re: General Mens health question. Metformin if you don't have diabetes.
« Reply #1 on: January 12, 2019, 08:21:03 am »


Flyingfool

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Re: General Mens health question. Metformin if you don't have diabetes.
« Reply #2 on: January 12, 2019, 11:31:49 am »
I have been trying half dose of Berberine every day. I have read and maybe all propaganda sales hype. It other health sites claim that it is as effective as metformin without any side effects of metformin. Although metformin has pretty few sides.

I have not gotten retested since I started the 500mg per day dose. So I have no data to support whether it is effective or not yet. If it shows signs of improvement, I will probanly up the dose to the recommended serving size listed on the bottle of two 500 mg capsules a day.

I think there is another supplement called PPQ, which may be even more effective than Berberine for glucose control. But I have not really looked into that any further.

Advantage of Berberine is no need for for a prescription and can order OTC online.
52 year old, 5-7 and 165 lbs.
exercise:swim 3x/wk & marrial arts 2x/wk

Blood tested 9/19/18

Total = 580 ng/dL (250-827) 59.9%
Free T= 6.87 (4.6- 22.4) 12.8% (10.8 calc)

SHBG= 39 10.0-50.0) 72.5%

Bio-avail= 14.2 (110-575) 8.0%

DHES =not tested %

Estradiol = 22 (<39)

DHES =231 (38-313) =45.5% tested 2/14/18

Currently on 50mcg Synthroid (T4)
TSH = 0.99
Free T4 = 1.30 (0.80 - 1.80)  =50.0% of range
Free T3 = 3.3 (2.3-4.2) = 52.6% of range
Current protocol: 100mg DIM once per day. Reduction back from 200 mg. For 12 weeks. raised total T, freeT remained basically unchanged due to increases SHBG. Estradiol decrease from 30 to 22. Felt no better and maybe worse than at 100mg DIM so going back starting 9/25/18

Paco1973

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Re: General Mens health question. Metformin if you don't have diabetes.
« Reply #3 on: January 14, 2019, 05:33:14 am »
Why add another medication if you don't need it? Seriously. Your blood sugar is fine. Less is more.
44 years old.
Protocol 0.1ml of 100mg per ml of Testosterone Propionate injected daily subcutaneously.
HCG 150iu daily
Anastrazole 0.05mg twice a week

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Re: General Mens health question. Metformin if you don't have diabetes.
« Reply #3 on: January 14, 2019, 05:33:14 am »