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Author Topic: Buserelin Acetate (for animals)  (Read 246 times)

PakMan

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Buserelin Acetate (for animals)
« on: January 24, 2019, 05:14:08 am »
After failure of TRT and HCG, I am excited about the prospects of micro dose GnRH agonists like Triptorelin or Leuprorelin etc.

However I found Buserelin Acetate. There is one case study for hypogonadism for this drug.

https://www.ncbi.nlm.nih.gov/pubmed/19591988

Another thing making me very happy is that it is very cheap equivalent to 2 US dollars. Less than one third the price of an HCG injection here.
One injection is 2.5 ml
Each ml contains Buserelin acetate 0.0042 mg equivalent to 0.004 mg Buserelin

There is one little problem.

Its made for Animals.
It says only for veterinary use.

Could the same inject-able drug that is made for animals be dangerous for humans even though the same formula is also used in Humans?

Would you try it?



Age: 46, HT: 5' 7'', WT: 75 kg

Jan 16 to Oct 16 - Test Enanthate (35mg 2x/week)
Oct 16 to Feb 17 - HCG (500iu 2x/Week)
Feb 17 - Test Propionate (25mg only 2 injections 4 days apart)
Aug 2017 onwards (Astaxanthin + other oils, supplements)
Dec 2017 Low dose TRT (25 mg twice a week)
Nothing from Jan 1, 2019

21/08/2017 8:10 PM
Total T = 271 ng/dl  (Range 160 - 726)
LH = 5.15 mIU/ml  (Range 0.8 - 7.6)

Cataceous

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Re: Buserelin Acetate (for animals)
« Reply #1 on: January 24, 2019, 06:11:50 am »
Is the manufacturer known and reputable? Are quality standards like USP also used for veterinary medications? Theoretically, if standards are lower for veterinary medications then there could be higher levels of impurities. But it's also possible sources and methods are the same.

Would I do it myself? Maybe, depending on finances, etc...
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 57, Ht: 5'10", Wt: 158 lbs
Protocol: 18 mg T enanthate subQ qod, 250 IU hCG subQ qod, 70 mcg anastrozole qod, 6.25 mg DHEA orally bid
7-12/2018 test results: TT: 800 ng/dL, E2: 31 pg/mL LC/MS-MS, DHEA-S: 264 ug/dL (49-344)—SHBG ~30 nmol/L

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Re: Buserelin Acetate (for animals)
« Reply #1 on: January 24, 2019, 06:11:50 am »


golfboy307

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Re: Buserelin Acetate (for animals)
« Reply #2 on: January 24, 2019, 09:14:27 am »
Has it even been tested on humans?
Age 51, 5'10, 155 lbs
Cholesterol 162 (HDL 59, LDL 87, Trigs 88, LDL-P 850)
Fasting Glucose 65 (down from 97 pre TRT)
A1C:  5.0 (down from 5.7 per TRT)
Homocysteine:  12.4 > 11.0 > 10.2 > 8.9 using B vitamin therapy.  MTHFR positive 

BP  120/78 (using improved diet and 10 mg Lisinopril ACE Inhibitor)  145/90 prior to meds.

Current protocol:  60 mg Test Cyp IM every 5 days.  No AI.
2/15/17 labs:  Total T (peak day): 1169 (250 - 1100 ng/dl).  Free T 198 pg/ML (46-225).  Sensitive E2: 40 High.  Previously 32. PSA 0.2  Hemocrit 44.2. SHBG: 32
9/15/18 labs:  Total T (trough day):  598 (250 -1100 ng/dl)  Free T 73.9 (46-225) Sensitive E2: 21  Hemocrit 43.7  SHBG 34
2/20/19 labs:  Total T (mid point):  776 (250 -1100 ng/dl) Free T 115.6 (46 - 224 pg/ml) Sensitive E2 24 (<29), DHT 43 (16-79 ng), DHEA-s 244 (70-495 mcg/dl)


Supplements:  Multivitamin, plus additional B12, B6, C, D, K2, Red Yeast Rice, Magnesium, and Coq10  Evening:  Kyolic Garlic, 2mg Cialis, LEF Endothelial Protection

Cataceous

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Re: Buserelin Acetate (for animals)
« Reply #3 on: January 24, 2019, 10:14:48 am »
Has it even been tested on humans?

Yes, it has a number of human uses. It just hasn't been approved in the U.S. for whatever reason.

Quote from: Wikipedia
Buserelin, sold under the brand name Suprefact among others, is a medication which is used primarily in the treatment of prostate cancer and endometriosis.[3][1][2] It is also used for other indications such as the treatment of premenopausal breast cancer, uterine fibroids, and early puberty, in assisted reproduction for female infertility, and as a part of transgender hormone therapy.[6][3][7] In addition, buserelin is used in veterinary medicine.
...
... It is not available in the United States, but is marketed widely elsewhere in the world, including in the United Kingdom, Canada, and many other countries.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 57, Ht: 5'10", Wt: 158 lbs
Protocol: 18 mg T enanthate subQ qod, 250 IU hCG subQ qod, 70 mcg anastrozole qod, 6.25 mg DHEA orally bid
7-12/2018 test results: TT: 800 ng/dL, E2: 31 pg/mL LC/MS-MS, DHEA-S: 264 ug/dL (49-344)—SHBG ~30 nmol/L

Peak Testosterone Forum

Re: Buserelin Acetate (for animals)
« Reply #3 on: January 24, 2019, 10:14:48 am »


PakMan

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Re: Buserelin Acetate (for animals)
« Reply #4 on: January 26, 2019, 02:51:55 am »
Is the manufacturer known and reputable? Are quality standards like USP also used for veterinary medications? Theoretically, if standards are lower for veterinary medications then there could be higher levels of impurities. But it's also possible sources and methods are the same.

Would I do it myself? Maybe, depending on finances, etc...

Ok I tried 0.1 ml which is too small. Did feel slightly high libido but that may have nothing to do with it. Also felt a bit weird. Any way I decided not to continue with it. Instead I will try Leuprorelin proper for human beings. It does cost 30 times more but better safe than sorry. It would be nice if any one has tried it or knows a thing or two about it to share it here.
« Last Edit: January 26, 2019, 02:54:24 am by PakMan »
Age: 46, HT: 5' 7'', WT: 75 kg

Jan 16 to Oct 16 - Test Enanthate (35mg 2x/week)
Oct 16 to Feb 17 - HCG (500iu 2x/Week)
Feb 17 - Test Propionate (25mg only 2 injections 4 days apart)
Aug 2017 onwards (Astaxanthin + other oils, supplements)
Dec 2017 Low dose TRT (25 mg twice a week)
Nothing from Jan 1, 2019

21/08/2017 8:10 PM
Total T = 271 ng/dl  (Range 160 - 726)
LH = 5.15 mIU/ml  (Range 0.8 - 7.6)

Peak Testosterone Forum

Re: Buserelin Acetate (for animals)
« Reply #4 on: January 26, 2019, 02:51:55 am »