Youíll be surprised what TRT can do. I too suffer from depression/anxiety. Iím on ssri Paxil, after being on 100mg of test cyp weekly my depression has gotten a lot better, and so has my anxiety. You can take the two together, Iíve ask both my endo and psychiatrist. You build more confidence in yourself. You can control your red blood cell levels by the amount of test you take. I give blood a 3-4 times a year which helps out, plus you are helping others. If I hadnít started TRT, I would be a total mess mentally. I personally think if people who are on it and donít feel better, they may not have found the right dose and protocol. For me, 50mg shots every 3.5 days is perfect. I donít need anymore than that, otherwise my E2 and red blood cells will start to go up. Plus Iíve always lifted weights, and it gives me the right amount of drive in the gym.