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Author Topic: Dopamine Agonist - Pramipexole  (Read 818 times)

kregger

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Dopamine Agonist - Pramipexole
« on: January 02, 2020, 07:46:58 pm »
I'm more of a lurker on this forum than a poster but I just wanted to post this in case anybody out there is at their wits end with libido issues. I've found reasonable success with Pramipexole at 0.5mg once daily. I don't understand how it works but it seems to basically inhibit prolactin. Whenever prolactin is inhibited, libido tends to increase. That's my "bro science" take on it, but I'm sure you can look into much deeper and glean more details. Apparently this medication is mostly intended for Parkinson's patients, and long term use could result in motor problems and/or other problems. I'm not a medical doctor/advisor so do your own research and use at your own risk.
1st Labs:
Total Testosterone: 497 (range is 348 - 1197)
Free Testosterone: 6.1 (range is 8.7 - 25.1)
DHEA: 204.2 (range is 102.6 - 416.3)
Luteinizing Hormone: 9.8 (range is 1.7 - 8.6)
Estradiol: 16.2 (range is 8.0 - 35.0)

Started 25mg daily Clomid (through Defy Medical) on 11/03/16

2nd Labs:
Total Testosterone: 962 (range is 348 - 1197)
Free Testosterone: 12.0 (range is 8.7 - 25.1)
DHEA: 377.5 (range is 102.6 - 416.3)
Luteinizing Hormone: 11.4 (range is 1.7 - 8.6)
Estradiol: 26.1 (range is 8.0 - 35.0)

Cataceous

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Re: Dopamine Agonist - Pramipexole
« Reply #1 on: January 02, 2020, 08:30:24 pm »
Almost 250 posts means you're hardly a lurker!

Any thoughts on how pramipexole compares to cabergoline? It seems to be a lot more specific to the dopamine receptors. Does that give it a better side effects profile? The half-life is a lot shorter, 8-12 hours, so I assume that's why at least daily dosing is needed.
« Last Edit: January 02, 2020, 08:32:44 pm by Cataceous »
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 59, Ht: 5'10", Wt: 154 lbs
Protocol: 2.4 mg T propionate subQ qd, 3.2 mg T enanthate qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

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Re: Dopamine Agonist - Pramipexole
« Reply #1 on: January 02, 2020, 08:30:24 pm »


kregger

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Re: Dopamine Agonist - Pramipexole
« Reply #2 on: January 02, 2020, 10:31:41 pm »
I've never tried Cabergoline. When I read that even older folks refer to Mirapex as "Mirasex" I figured if it even worked for them, it'd be worth trying.
1st Labs:
Total Testosterone: 497 (range is 348 - 1197)
Free Testosterone: 6.1 (range is 8.7 - 25.1)
DHEA: 204.2 (range is 102.6 - 416.3)
Luteinizing Hormone: 9.8 (range is 1.7 - 8.6)
Estradiol: 16.2 (range is 8.0 - 35.0)

Started 25mg daily Clomid (through Defy Medical) on 11/03/16

2nd Labs:
Total Testosterone: 962 (range is 348 - 1197)
Free Testosterone: 12.0 (range is 8.7 - 25.1)
DHEA: 377.5 (range is 102.6 - 416.3)
Luteinizing Hormone: 11.4 (range is 1.7 - 8.6)
Estradiol: 26.1 (range is 8.0 - 35.0)

Cataceous

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Re: Dopamine Agonist - Pramipexole
« Reply #3 on: January 03, 2020, 03:19:07 am »
It does sound interesting, and for the adventurous it's available at AllDayChemist.com without a prescription.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 59, Ht: 5'10", Wt: 154 lbs
Protocol: 2.4 mg T propionate subQ qd, 3.2 mg T enanthate qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

Peak Testosterone Forum

Re: Dopamine Agonist - Pramipexole
« Reply #3 on: January 03, 2020, 03:19:07 am »