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Author Topic: Clomid  (Read 1615 times)

guil70

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Clomid
« on: December 01, 2020, 07:52:13 pm »
Well..., I went to the urologist today and he wants me to take clomid and he wants a testosterone test lab in 6 weeks, he wants this first to enter me in TRT, I appreciate any comment, any help, from people who is using or have used clomid. I also want to know what is the best to time a day to take it.

golfboy307

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Re: Clomid
« Reply #1 on: December 01, 2020, 09:59:29 pm »
You mentioned in your other post you are 62 right?  Not sure if Clomid will help with an aging system as much as in younger guys.  Cataceous can chime in a bit here.  I briefly considered that route, but glad I went to TRT. 

Don't judge the Clomid results as indicative of TRT.  You can get some bump in numbers, but due to estrogenic effects you may not feel better on it.
Age 51, 5'10, 155 lbs
Cholesterol 162 (HDL 59, LDL 87, Trigs 88, LDL-P 850)
Fasting Glucose 65 (down from 97 pre TRT)
A1C:  5.0 (down from 5.7 per TRT)
Homocysteine:  12.4 > 11.0 > 10.2 > 8.9 using B vitamin therapy.  MTHFR positive 

BP  120/78 (using improved diet and 10 mg Lisinopril ACE Inhibitor)  145/90 prior to meds.

Current protocol:  60 mg Test Cyp IM every 5 days.  No AI.
2/15/17 labs:  Total T (peak day): 1169 (250 - 1100 ng/dl).  Free T 198 pg/ML (46-225).  Sensitive E2: 40 High.  Previously 32. PSA 0.2  Hemocrit 44.2. SHBG: 32
9/15/18 labs:  Total T (trough day):  598 (250 -1100 ng/dl)  Free T 73.9 (46-225) Sensitive E2: 21  Hemocrit 43.7  SHBG 34
2/20/19 labs:  Total T (mid point):  776 (250 -1100 ng/dl) Free T 115.6 (46 - 224 pg/ml) Sensitive E2 24 (<29), DHT 43 (16-79 ng), DHEA-s 244 (70-495 mcg/dl)


Supplements:  Multivitamin, plus additional B12, B6, C, D, K2, Red Yeast Rice, Magnesium, and Coq10  Evening:  Kyolic Garlic, 2mg Cialis, LEF Endothelial Protection

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Re: Clomid
« Reply #1 on: December 01, 2020, 09:59:29 pm »


guil70

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Re: Clomid
« Reply #2 on: December 01, 2020, 11:23:09 pm »
You mentioned in your other post you are 62 right?  Not sure if Clomid will help with an aging system as much as in younger guys.  Cataceous can chime in a bit here.  I briefly considered that route, but glad I went to TRT. 

Don't judge the Clomid results as indicative of TRT.  You can get some bump in numbers, but due to estrogenic effects you may not feel better on it.

Yes, I will be 62 soon, he wants me to take Clomid for 6 weeks in order to know if my erectile  dysfunction is "fully androgenic"  he said, I will do a try if I see nothing I will go to TRT for sure.

ghce

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Re: Clomid
« Reply #3 on: December 02, 2020, 01:22:02 am »
Generally ED is worsened by Clomid though everyone is different.
I have been on Clomid protocols 3 times in the last 5 years my reasons for doing so were purely fertility purposes.
Age:59, Height 6' 3" weight 92.5KG
2014 Androderm Patches
2014-2016 Oral Andriol 160mg Daily
June 2016 Clomid/Serophene 12.5mg EOD
September 2016 no TRT all natural and supplements for the time being
February 2017 Testosterone cream 100mg daily

Sept 2016
Testosterone   8.2 nmol/l   9-38
Free Testosterone   239 pmol/l   L   250-800
SHBG:  14    nmol/L   9-60
Free Androgen index   586   >400
Oestradiol    112   pmol/L    <190
LH    2.6 IU/L Adult male   2 - 9 IU/L
FSH  1.4 IU/L Adult male L2 - 12 IU/L

22 November
T 6.8  nmol/L ( 9-38 ) L

March 2017
Testosterone:   45.0  nmol/L ( 9-38 ) H ( 1,323 ng/dl )
Free Testosterone:   1512  pmol/L ( 250-800 ) H
SHBG:   17  nmol/L ( 9-60 )
Plasma IGF-1:   227 ug/L ( 55-198 ) H
Plasma cortisol:   434 nmol/L ( 0600-1000 hrs 170-500 nmol/L )
HbA1c:   36 mmol/mol ( 20-40 )
LH:   <0.1 IU/L
FSH:   0.1 IU/L
DHT Plasma Dihydrotestosterone:   7455   pmol/L ( 223 ng/dl ) 
Reference Range Adult males  1000-6000 pmol/L

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Re: Clomid
« Reply #3 on: December 02, 2020, 01:22:02 am »


guil70

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Re: Clomid
« Reply #4 on: December 02, 2020, 09:26:25 am »
I will do a try, it will be a six weeks test, if it is worsened I will go on TRT, in case of being positive, when I would see any difference?

ghce

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Re: Clomid
« Reply #5 on: December 02, 2020, 10:59:55 am »
1 to 2 weeks it should be noticeable, you may get a honeymoon period to about 3 to 5 weeks then it will likely settle for better or worse.
Age:59, Height 6' 3" weight 92.5KG
2014 Androderm Patches
2014-2016 Oral Andriol 160mg Daily
June 2016 Clomid/Serophene 12.5mg EOD
September 2016 no TRT all natural and supplements for the time being
February 2017 Testosterone cream 100mg daily

Sept 2016
Testosterone   8.2 nmol/l   9-38
Free Testosterone   239 pmol/l   L   250-800
SHBG:  14    nmol/L   9-60
Free Androgen index   586   >400
Oestradiol    112   pmol/L    <190
LH    2.6 IU/L Adult male   2 - 9 IU/L
FSH  1.4 IU/L Adult male L2 - 12 IU/L

22 November
T 6.8  nmol/L ( 9-38 ) L

March 2017
Testosterone:   45.0  nmol/L ( 9-38 ) H ( 1,323 ng/dl )
Free Testosterone:   1512  pmol/L ( 250-800 ) H
SHBG:   17  nmol/L ( 9-60 )
Plasma IGF-1:   227 ug/L ( 55-198 ) H
Plasma cortisol:   434 nmol/L ( 0600-1000 hrs 170-500 nmol/L )
HbA1c:   36 mmol/mol ( 20-40 )
LH:   <0.1 IU/L
FSH:   0.1 IU/L
DHT Plasma Dihydrotestosterone:   7455   pmol/L ( 223 ng/dl ) 
Reference Range Adult males  1000-6000 pmol/L

Cataceous

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Re: Clomid
« Reply #6 on: December 02, 2020, 01:30:51 pm »
Are you U.S.-based? If so I would press the doctor to prescribe enclomiphene instead. Clomid consists of two isomers, enclomiphene and zuclomiphene. Enclomiphene does the useful part, stimulating natural hormone production. Zuclomiphene, on the other hand, is estrogenic and frequently throws things out of whack. Enclomiphene is available through Tailor Made Compounding Pharmacy. I am using it and can vouch for its effectiveness.

What ghce says is true: SERMs like Clomid may be less effective in older guys like us because our natural hormone production capabilities are going down with age. Nonetheless I think it's worth trying. TRT has its own complications, such as shutting down many upstream hormones. This can lead to secondary problems.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 59, Ht: 5'10", Wt: 154 lbs
Protocol: 2.4 mg T propionate subQ qd, 3.2 mg T enanthate qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

seppuku

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Re: Clomid
« Reply #7 on: December 02, 2020, 02:08:53 pm »
Are you U.S.-based? If so I would press the doctor to prescribe enclomiphene instead. Clomid consists of two isomers, enclomiphene and zuclomiphene. Enclomiphene does the useful part, stimulating natural hormone production. Zuclomiphene, on the other hand, is estrogenic and frequently throws things out of whack. Enclomiphene is available through Tailor Made Compounding Pharmacy. I am using it and can vouch for its effectiveness.

What ghce says is true: SERMs like Clomid may be less effective in older guys like us because our natural hormone production capabilities are going down with age. Nonetheless I think it's worth trying. TRT has its own complications, such as shutting down many upstream hormones. This can lead to secondary problems.

Are you using enclomiphene as a monotherapy Cataceous, or along with trt?

Cataceous

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Re: Clomid
« Reply #8 on: December 02, 2020, 02:45:40 pm »
...
Are you using enclomiphene as a monotherapy Cataceous, or along with trt?

I'm using it with TRT so that gonadorelin can be used as a replacement for hCG. It started as an experiment, but the results have been so good that it has evolved into a long-term protocol.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 59, Ht: 5'10", Wt: 154 lbs
Protocol: 2.4 mg T propionate subQ qd, 3.2 mg T enanthate qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

guil70

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Re: Clomid
« Reply #9 on: December 02, 2020, 11:27:04 pm »
Are you U.S.-based? If so I would press the doctor to prescribe enclomiphene instead. Clomid consists of two isomers, enclomiphene and zuclomiphene. Enclomiphene does the useful part, stimulating natural hormone production. Zuclomiphene, on the other hand, is estrogenic and frequently throws things out of whack. Enclomiphene is available through Tailor Made Compounding Pharmacy. I am using it and can vouch for its effectiveness.

What ghce says is true: SERMs like Clomid may be less effective in older guys like us because our natural hormone production capabilities are going down with age. Nonetheless I think it's worth trying. TRT has its own complications, such as shutting down many upstream hormones. This can lead to secondary problems.

Yes, I am US based, I will let know the doctor about enclomiphene, Thank you.

Another questions, any conflict between Clomid and Viagra, Cialis, Levitra?, can I take any of them normally?

Cataceous

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Re: Clomid
« Reply #10 on: December 03, 2020, 12:53:13 am »
...
Another questions, any conflict between Clomid and Viagra, Cialis, Levitra?, can I take any of them normally?

I haven't heard about any serious interactions between Clomid and the various PDE5 inhibitors. Might as well ask your doctor too, but I think it's safe to use them normally.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 59, Ht: 5'10", Wt: 154 lbs
Protocol: 2.4 mg T propionate subQ qd, 3.2 mg T enanthate qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

guil70

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Re: Clomid
« Reply #11 on: December 04, 2020, 01:02:06 am »
I got this lab test the day before starting Clomid, notice the testosterone  total increased with respect the last three results  I had, I don't know why?, could this be due to ashwagandha?

 
 Testosterone, Serum 300 ng/dL       264-916

 Free Testosterone(Direct) 10.4 pg/mL            6.6-18.1 BN
 
 DHEA-Sulfate 241.0 ug/dL       48.9-344.2 TA
 
 Estradiol 24.7 pg/mL          7.6-42.6 TA

 Prostate Specific Ag, Serum 0.6 ng/mL        0.0-4.0 TA


« Last Edit: December 04, 2020, 02:20:16 am by guil70 »

Cataceous

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Re: Clomid
« Reply #12 on: December 04, 2020, 12:04:36 pm »
Natural testosterone can be quite variable, so you can't be sure of the reason for this particular change. Maybe ashwagandha helped, maybe not. In any case, 300 ng/dL is still hypogonadal.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 59, Ht: 5'10", Wt: 154 lbs
Protocol: 2.4 mg T propionate subQ qd, 3.2 mg T enanthate qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

guil70

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Re: Clomid
« Reply #13 on: December 05, 2020, 12:38:34 am »
Natural testosterone can be quite variable, so you can't be sure of the reason for this particular change. Maybe ashwagandha helped, maybe not. In any case, 300 ng/dL is still hypogonadal.

Yes, I know it is still low, but it is curious that it is the higher value I have had after having three consecutive results being lower every time, I also think that cialis daily use could has helped, anyway I am under  the 6 weeks Clomid treatment.

Cataceous

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Re: Clomid
« Reply #14 on: December 05, 2020, 03:37:49 pm »
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 59, Ht: 5'10", Wt: 154 lbs
Protocol: 2.4 mg T propionate subQ qd, 3.2 mg T enanthate qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

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Re: Clomid
« Reply #14 on: December 05, 2020, 03:37:49 pm »