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Author Topic: Libido Labs  (Read 211 times)

MidlifeSquatBench

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Libido Labs
« on: February 19, 2021, 09:53:37 pm »
Hi, I've been off everything for a couple of years and didn't even have a regular doc for a while. I've been struggling with the usual hyperthyroid problems. Libido disappeared and here are my latest labs at age 45. Any thoughts? The next available appointment with my new specialist is several weeks away.

Testosterone    556, rr 300-890 nG/dL
Sex Horm BG     58.1, rr 16.5-55.9 nMOL/L *******High********
Calc Free Test  80.8, rr 47.0-244.0 PG/mL
Estradiol       <17.0, rr <=60.7 PG/mL

FREE T4 (THYROXINE)   2.21, rr 0.80-1.90 NG/dL       *******Low*******
TSH REFLEX TO FREE T4 <0.010, rr 0.400-4.100 UIU/mL  *******Low*******
« Last Edit: February 19, 2021, 10:22:28 pm by MidlifeSquatBench »

ghce

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Re: Libido Labs
« Reply #1 on: February 19, 2021, 11:32:55 pm »
From my recent research it seems Prolactin is a big determiner of libido and ED, would pay to get those tested in your next set of bloods.
Age:59, Height 6' 3" weight 92.5KG
2014 Androderm Patches
2014-2016 Oral Andriol 160mg Daily
June 2016 Clomid/Serophene 12.5mg EOD
September 2016 no TRT all natural and supplements for the time being
February 2017 Testosterone cream 100mg daily

Sept 2016
Testosterone   8.2 nmol/l   9-38
Free Testosterone   239 pmol/l   L   250-800
SHBG:  14    nmol/L   9-60
Free Androgen index   586   >400
Oestradiol    112   pmol/L    <190
LH    2.6 IU/L Adult male   2 - 9 IU/L
FSH  1.4 IU/L Adult male L2 - 12 IU/L

22 November
T 6.8  nmol/L ( 9-38 ) L

March 2017
Testosterone:   45.0  nmol/L ( 9-38 ) H ( 1,323 ng/dl )
Free Testosterone:   1512  pmol/L ( 250-800 ) H
SHBG:   17  nmol/L ( 9-60 )
Plasma IGF-1:   227 ug/L ( 55-198 ) H
Plasma cortisol:   434 nmol/L ( 0600-1000 hrs 170-500 nmol/L )
HbA1c:   36 mmol/mol ( 20-40 )
LH:   <0.1 IU/L
FSH:   0.1 IU/L
DHT Plasma Dihydrotestosterone:   7455   pmol/L ( 223 ng/dl ) 
Reference Range Adult males  1000-6000 pmol/L

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Re: Libido Labs
« Reply #1 on: February 19, 2021, 11:32:55 pm »


Cataceous

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Re: Libido Labs
« Reply #2 on: February 20, 2021, 02:33:30 am »
Free testosterone is borderline low when calculated by either Vermeulen or Tru-T. It's possible to have some low-T symptoms at these levels, depending on the individual. Of equal or greater concern is the likelihood of low estradiol. Estradiol is an important contributor to libido. There's no sure-fire way for a guy with a functional HPTA to raise estradiol without suppressing testosterone. Probably use of a SERM is the best bet. Given that SHBG is high, enclomiphene is preferred over Clomid. Although some of the estrogenic effects of Clomid might be beneficial when estradiol is low, the likely further increase in SHBG could prevent gains in free testosterone.

As ghce says, prolactin is worth testing. The low estradiol removes one possible cause of elevated prolactin, but there are certainly others.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 59, Ht: 5'10", Wt: 154 lbs
Protocol: 2.4 mg T propionate subQ qd, 3.2 mg T enanthate qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

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Re: Libido Labs
« Reply #2 on: February 20, 2021, 02:33:30 am »