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Author Topic: Sleep is worse while on TRT  (Read 904 times)

browns1957

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Sleep is worse while on TRT
« on: June 01, 2021, 04:58:47 pm »
I've been on TRT with male excel about 6 months now - they have me on .22ml / 40 mg a day.  No recent or updated blood test to report.  My comment is that I seem to have worse sleep quality now - to the point I am up until 6am every day, which in turn has other negative effects and makes it hard to discern the benefits of TRT - i.e. energy, erection quality, etc...

Anybody else have a similar issue?  If I am going to reduce my dosage - should I do a gradual decline - for example down to .10ml / 20 mg a day or less - or just cycle off for a week or two - i'm not sure if this is the root of my issues, but looking if anybody has similar experiences...

Cataceous

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Re: Sleep is worse while on TRT
« Reply #1 on: June 01, 2021, 08:50:01 pm »
It is common for higher doses of testosterone to be stimulatory and interfere with sleep. I can't even inject testosterone in the evening without having sleep problems. I'd suggest you get your lab work done as soon as possible and then cut back to 14 mg TC per day. It's likely you will have some withdrawal symptoms for at least a month or two, so be mentally prepared to carry through. If good overall health is the desired endpoint then you should aim to use physiological amounts of testosterone.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 60, Ht: 5'10", Wt: 154 lbs
Protocol: 3.2 mg TE subQ qd, 2.4 mg TP subQ qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

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Re: Sleep is worse while on TRT
« Reply #1 on: June 01, 2021, 08:50:01 pm »


StephCurryFtw

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Re: Sleep is worse while on TRT
« Reply #2 on: June 02, 2021, 05:14:20 am »
Yeah TRT has always made my sleep worse at higher doses. That is totally normal.
December 17th, 2020:

TT: 543.85 ng/dL (245-970 ng/dL)
FT: 11.82 pg/mL (47-293 pg/mL)
Prolactin: 25.76 ng/mL (3-13 ng/mL)
SHBG: 8.69 nmol/L (10-40 nmol/L)
E2: 25.26 pg/mL (10-40 pg/mL)
DHEA-S: 629.71 mg/dL (280-640 mg/dL)
Cortisol @ 8 A.M.: 23.64 mcg/dL (10-20 mcg/dL)
TSH: 2.38 mIU/L (0.5-4.15 mIU/L)
T3: 137.63 ng/dL (100-200 ng/dL)
T4: 1.39 ng/dL (0.8-1.8 ng/dL)
(Reverse) T3: 15.37 ng/dL (9.2-24.1 ng/dL)
FSH: 4.36 mIU/mL (1.5-12.4 mIU/mL)
LH: 3.66 IU/L (1.24-7.8 IU/L)

StephCurryFtw

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Re: Sleep is worse while on TRT
« Reply #3 on: June 02, 2021, 05:14:50 am »
It is common for higher doses of testosterone to be stimulatory and interfere with sleep. I can't even inject testosterone in the evening without having sleep problems. I'd suggest you get your lab work done as soon as possible and then cut back to 14 mg TC per day. It's likely you will have some withdrawal symptoms for at least a month or two, so be mentally prepared to carry through. If good overall health is the desired endpoint then you should aim to use physiological amounts of testosterone.

Months of withdrawals damnů :(
December 17th, 2020:

TT: 543.85 ng/dL (245-970 ng/dL)
FT: 11.82 pg/mL (47-293 pg/mL)
Prolactin: 25.76 ng/mL (3-13 ng/mL)
SHBG: 8.69 nmol/L (10-40 nmol/L)
E2: 25.26 pg/mL (10-40 pg/mL)
DHEA-S: 629.71 mg/dL (280-640 mg/dL)
Cortisol @ 8 A.M.: 23.64 mcg/dL (10-20 mcg/dL)
TSH: 2.38 mIU/L (0.5-4.15 mIU/L)
T3: 137.63 ng/dL (100-200 ng/dL)
T4: 1.39 ng/dL (0.8-1.8 ng/dL)
(Reverse) T3: 15.37 ng/dL (9.2-24.1 ng/dL)
FSH: 4.36 mIU/mL (1.5-12.4 mIU/mL)
LH: 3.66 IU/L (1.24-7.8 IU/L)

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Re: Sleep is worse while on TRT
« Reply #3 on: June 02, 2021, 05:14:50 am »


browns1957

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Re: Sleep is worse while on TRT
« Reply #4 on: June 02, 2021, 02:24:20 pm »
Would it be better to cycle off for 1-2 weeks completely to lower the internal absorption, or continue , but with a much lower dosage as you indicated?

Cataceous

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Re: Sleep is worse while on TRT
« Reply #5 on: June 02, 2021, 08:18:10 pm »
If you really want to lower testosterone as fast as possible then you can calculate roughly how long to cycle off. If you're looking to reduce the dose to a third of what it was and assuming a half-life of five days then the "off" cycle is about eight days.

This is faster, though not necessarily better. It's possible that the slower drop in testosterone caused by a switch to a lower dose without an off cycle would feel marginally better. But either way it may not feel very good for some period of time.
I am not a medical doctor; any suggestions are meant to be discussed with your doctor.
Age: 60, Ht: 5'10", Wt: 154 lbs
Protocol: 3.2 mg TE subQ qd, 2.4 mg TP subQ qd, 20 mcg GnRH subQ 5.25x/d, 6.25 mg DHEA bid, 12.5 mg enclomiphene qod
Approximate levels (peak): TT: 700 ng/dL, E2: 30 pg/mL, DHEA-S: 300 ug/dL, SHBG: 30 nMol/L

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Re: Sleep is worse while on TRT
« Reply #5 on: June 02, 2021, 08:18:10 pm »