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Author Topic: Fatty liver disease diagnostics  (Read 3681 times)

Kwn

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Fatty liver disease diagnostics
« on: January 28, 2014, 05:34:59 pm »
How is fatty liver disease diagnosed?

Anyone had experience with it?

PeakT

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Re: Fatty liver disease diagnostics
« Reply #1 on: January 28, 2014, 05:50:30 pm »
How is fatty liver disease diagnosed?

Anyone had experience with it?

It's tough to diagnose from what I have read - kind of like using PSA with prostate cancer.  There's no perfect test yet.  I believe that an ultrasound and/or biopsy is the final step, but here are some nice diagnostic signals to look for:

http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/hepatology/nonalcoholic-fatty-liver-disease/

"In a patient with suspected NAFLD or NASH, useful baseline testing should include levels of AST, ALT, total and direct bilirubin, and fasting serum glucose, as well as a lipid panel. Mild to moderate elevation of serum aminotransferase levels is most commonly found (mean range, 100-200 IU/L). Generally, the ratio of AST to ALT is <1, but this ratio increases as fibrosis advances. Liver enzyme levels are normal in a large percentage of patients with NAFLD; normal aminotransaminase levels do not exclude the presence of advanced disease. Serum alkaline phosphatase and g-glutamyl transpeptidase levels may also be mildly abnormal. Given that more than 80% of patients with NAFLD have some components of metabolic syndrome, serum levels of fasting cholesterol and triglycerides, as well as fasting glucose and insulin, should be determined. Albumin, bilirubin, and platelet levels are usually normal unless the disease has evolved to cirrhosis. Some patients with NAFLD have low titers of autoimmune antibodies (antinuclear and anti–smooth muscle antibody) and an elevation of ferritin. The role of these markers is still unclear."
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Re: Fatty liver disease diagnostics
« Reply #1 on: January 28, 2014, 05:50:30 pm »


PeakT

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Re: Fatty liver disease diagnostics
« Reply #2 on: January 28, 2014, 05:52:05 pm »
And I'll make an obvious point:

Because it's so tough to diagnose in the early stages, it behooves to play it ultra safe by keeping the weight off and making sure our insulin/blood glucose levels are in line.
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And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Sam

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Re: Fatty liver disease diagnostics
« Reply #3 on: January 28, 2014, 09:17:47 pm »
The other thing of note is that most docs will tell you its completely reversible at this stage, so knowing you have it only reinforces the need to keep striving to live a healthier lifestyle.

If you have low SHBG and go for a Liver ultrasound the more important thing is probably to rule out any more seriious liver issues that could complicate recovery.

I keep telling myself it took me 40 years to get here so I cannot expect it to take months or even a couple years to turn it around.

Although i do believe if 1) I knew when I started this what I know now, I would have saved alot of money by getting the right tests run the first time.   i.e. CBG, SHBG Total and Free Testosterone, Total and Free Cortisol and a 24hr Urine Hormone Panel.  Then standard CBC and lipid panels to monitor progress.   I probably would have started TRT earlier and stayed with it.  Oh,  and drank more coffee...

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Re: Fatty liver disease diagnostics
« Reply #3 on: January 28, 2014, 09:17:47 pm »


davie12

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Re: Fatty liver disease diagnostics
« Reply #4 on: January 28, 2014, 10:14:16 pm »
This is why I'm a big fan of trying to take medications sublingually or through injections. The liver has enough of a job to do without putting extra medications through it. If you screw around with this organ, you really can f@#k yourself up. Alcohol, cholesterol, popping pills unnecessarily over a number of years can do damage. Read this link: http://livertox.nih.gov/Phenotypes_Fatty.html

Take note that one of the case studies is someone taking Tamoxifen. That is sometimes used for low T guys. In fact, I remember Dr Shippen mentioning that it is one of his tools he sometimes uses. And even that person has some liver issues...granted it was a woman taking it for breast cancer.

I'm not saying to not take pills if you really need them. I just know people who pop pills like they're candy. Only take the ones you really absolutely need.  :o
Recovering from adrenal fatigue through Paleo diet+exercise+vitamins/supplements; formerly used HCG & Clomid at various dosages

PeakT

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Re: Fatty liver disease diagnostics
« Reply #5 on: January 28, 2014, 10:35:14 pm »
This is why I'm a big fan of trying to take medications sublingually or through injections. The liver has enough of a job to do without putting extra medications through it. If you screw around with this organ, you really can f@#k yourself up. Alcohol, cholesterol, popping pills unnecessarily over a number of years can do damage. Read this link: http://livertox.nih.gov/Phenotypes_Fatty.html

Take note that one of the case studies is someone taking Tamoxifen. That is sometimes used for low T guys. In fact, I remember Dr Shippen mentioning that it is one of his tools he sometimes uses. And even that person has some liver issues...granted it was a woman taking it for breast cancer.

I'm not saying to not take pills if you really need them. I just know people who pop pills like they're candy. Only take the ones you really absolutely need.  :o

Quite a few supplements have been under fire lately for being hard on the liver.  If you're taking green tea extract, be careful.  Just posted on this here:

https://www.peaktestosterone.com/forum/index.php?topic=3190.0

You only have one liver, eh?
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

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Re: Fatty liver disease diagnostics
« Reply #5 on: January 28, 2014, 10:35:14 pm »