I am 22 years old and have suffered my symptoms since I was 18. I was always an overweight child where my weight in stones matched my age to the point where I was 16 years old and weighed 17 stone (240lbs) After this point my weight slowly reduced down to the 15 stone (210lbs) mark which it remained until I reached 21 years old.
At 21 I decided to try and cut back as much weight and fat as possible, I was sitting at 15 stone 7lbs (220lbs) and through a low carb diet reduced my weight down to 158lbs. Even at this weight, I was standing at 6ft tall and still carrying excessive bodyfat (20% +). Without any success getting rid of the 'skinnyfat' physique' I plateaued back to 190-200lbs.
I visited my GP back in 2011 when I was 20 with my symptoms, after research I requested testosterone test, which came back at 13.7nmol (8.6-28.8 range). I was sent away and told my symptoms were psychological...
In 2012 I lost 48lbs, started cardio, lifting weights, changed my lifestyle for a period of over 8 months, nothing changed symptom wise so I went back to the doctor and requested another test, my blood testosterone came back at 12.5nmol (8.6-28.
I got a referral to an endocrinologist.
Jan 2013 I saw an endocrinologist, bloods were taken;
Serum test - 10.8nmol (8.6-28.
E2 222pmol (40-156)
SHBG 12.2nmol (18-45)
LH 6.5 (1-9)
FSH 6.5 (1-9)
March 2013 I saw endocrinologist again, bloods ;
Serum test - 11.5nmol (8.6-28.
E2 210pmol (40-156)
SHGB 12nmol (18-45)
LH 6.2 (1-9)
FSH 6.5 (1-9)
Endocrinologist told me that nothing was wrong, and gave me a prescription for Viagra. After speaking with my mother who is a medical professional, she went berserk. I researched and found out the NHS guidelines for doctors dealing with testosterone therapy. It stated that between 8-12nmol is a 'grey area' and doctors are guided to give a TRT trial. I sent these to my endocrinologist and he agreed a TRT trial.
I was started on a TRT trial March 2013. 1ml Sustanon250 injected one time every 4 weeks. After 2 months I was going crazy and being on this protocol was worse than pre TRT. I told my doctor the frequency is wrong and he agreed to change to 1ml sustanon250 every 3 weeks..... The first week my symptoms cleared, but I felt 'strange' and not normal. The second week I felt great! and the third week I felt terrible, symptoms were back. All of my trough bloods at weeks 3 and weeks 4 showed testosterone level below 8nmol! My trough at weeks 2 showed a level of 10nmol.
I continued on this treatment until September 2013 when a senior endocrinologist took over my case. Because I reported that my symptoms were coming back on treatment he stopped the TRT trial. I was taken off TRT cold turkey, which my HPTA shut down. I experienced exacerbated symptoms for 5 months which was complete hell. Daily for these 5 months my testicles tingled, and in Feb 2014 this sensation stopped, and my symptoms returned to a pre TRT state.
Results Feb 2014
Test 8.7 (8.6-28.
E2 156pmol (50-156)
SHBG 12nmol (18-45)
In Sept 2013 the Senior consultant stated that he wanted to start the case over with a baseline, and investigate every other mean because low SHGB could be an indicator of other medical illness/disease.
In Feb 2014 the senior consultant said that testosterone is a 'red herring' and that he thinks my issue is being overweight weight... (190lbs, 6ft tall) He thinks that if I loose my weight that everything will return to normal. I explained to him that I dropped to 158lbs! @ 6ft tall..... BF still high @ 20% + It is clearly a hormonal issue. He mentioned chronic fatigue syndrome as the next avenue.....
I have had the following tests and investigations; all came back OK.
Pituitary & Pineal MRI
Pelvic & Abdomen CT
Cortisol suppression test
XXY genetic testing
Mild Androgen insensitivity testing
DEXA bone scanFertility test - SPERM COUNT 0 (3 weeks on sustanon - possible false)
Full blood work (immune etc)
I have researched that low SHGB means lots of unbound free testosterone, which leads to higher levels of aromatization, and quicker clearance ,testosterone being metabolized. From this I believe that the trial of sustanon250 was the wrong choice for me? The initial large dosage causing a spike in E2 which could explain the feeling 'strange' during week1, and the return of symptoms during week 3 because of the testosterone clearance rate ? If sustanon was ever a choice again, the use of an AI, and a shorter frequency to combat the above issues,
I'm aware of the implications that long term TRT can cause. Whilst not ruling out another method of TRT, Fertility is important to me and I am keen to look at other types of treatment, the single use of an AI, or the use of a SERM, HCG/CLOMID to try and boot and support my own natural testosterone production.
I am looking for your thoughts and advice please, Also can anyone link me to medical reports of the use of AI, HCG and CLOMID so that I can print them off and show my doctor ?
These are my symptoms below. Also please find attached an image of my physique.
(note I had extreme difficulty typing this up, my cognitive function is terrible, trying to plan structure and content for this post had my mind turning like a pickle..... )
ZERO libido (no sexual desire, fantasy, never horny)
- Normal Erectile function
- NO MORNING ERRECTIONS
- poor orgasm & ejaculation
- Cold night sweats (soaking cold wet sheets, sweat smells very 'meaty')
- awaken daily feeling groggy - unrefreshed **worst symptom**
- Extremely irritable (with people)
- Non sociable (feel crap dont want to talk to people - See above)
- No enjoyment in life, hobbies, socializing.. no humor, no excitement. No goals.
- 'baseline' mood, not depressed, not miserable but not happy.
- Achey burning neck, shoulders (blades) upper arms.
- Nausea (mornings)
- Headspace is constantly muffled, like im in a vegative state.
- Poor concentration on tasks
- Poor short term memory.