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Author Topic: Confused with labs, could use some advice...  (Read 3430 times)

wvuguy2011

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Confused with labs, could use some advice...
« on: May 30, 2014, 12:42:03 am »
I posted here a while ago where I was on 50mg/day of clomid, and it appeared to not be working. However, I managed to convince my doctor to do 25mg/day for about ~8 months, and she did labs at the end - it appeared to work incredibly well. There were periodic labs during treatment that showed a steady climb, and this is where I was before she had me stop taking it completely:

LH: 36.5 mIU/mL [0.5-11]
TT: 907 ng/dL [240-950]
Bio T: 472 ng/dL [83-257] (really high??)
Prolactin: 17.5 ng/mL [3.5-15]

Felt great, things were good - perhaps prolactin a bit on the high side, but otherwise seemingly no issues. She discontinued and did labs about... 3/3.5 weeks after I took my last pill:

LH: 4.8 mIU/mL [0.5-11]
TT: 473 ng/dL [240-950]
Bio T: 114 ng/dL [83-257]

I got these labs before my appointment with her, so two days before I saw her, I went back on 25mg/day assuming she would want to continue. She instead asked me to stop, but for my curiosity, I grabbed labs a week after taking a pill and this is what I got:

LH: 10.3 mIU/mL [1.7-8.6]
TT: 746 ngdL [348-1197]
FT: 9.5 pg/mL [9.3-26.5]

Been a month and a day or so since my last pill and this is where I am:

LH: 4.2 mIU/mL [1.7-8.6]
Prolactin: 10.4 ng/mL [4-15.2]
E2: 18.5 pg/mL [7.6-42.6]
TT: 531 ng/dL [348-1197]
FT: 7.4 pg/mL [9.3-26.5]

This is good and yet bad... what the hell is up with my free T? Are there odds that the clomid is still doing something beyond a month, or is it something else? Things are a bit jumpy and I'm not enjoying it. Not much has changed diet-wise or anything. The only difference is that I'm taking this supplement: http://www.gnc.com/GNC-Mega-Men-Performance-Vitality/product.jsp?productId=25063036

Here's what I take from this:

  • Free T seems to be on the lower side
  • I respond well to clomid
  • Prolactin seems to go out of range once T gets into the higher ranges

Any ideas or thoughts?
Age: 24
Height: 5'11"
Weight: 150lbs

PeakT

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Re: Confused with labs, could use some advice...
« Reply #1 on: May 30, 2014, 03:54:13 am »
Clomid raises SHBG:

http://www.peaktestosterone.com/high_shbg

This will tend to lower free testosterone.
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
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And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

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Re: Confused with labs, could use some advice...
« Reply #1 on: May 30, 2014, 03:54:13 am »


wvuguy2011

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Re: Confused with labs, could use some advice...
« Reply #2 on: May 30, 2014, 11:27:40 am »
Clomid raises SHBG:

http://www.peaktestosterone.com/high_shbg

This will tend to lower free testosterone.

Wonderful - so it seems like clomid brings my T up but kills my free T? What about Bio T - is that truly a better comparison? If so, mine shot up really high after long-term clomid but I've now obviously dropped.

Never had a doctor draw SHBG, but if clomid raised it, shouldn't it have also dropped with discontinuation?
Age: 24
Height: 5'11"
Weight: 150lbs

PeakT

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Re: Confused with labs, could use some advice...
« Reply #3 on: May 30, 2014, 04:29:43 pm »
Clomid raises SHBG:

http://www.peaktestosterone.com/high_shbg

This will tend to lower free testosterone.

Wonderful - so it seems like clomid brings my T up but kills my free T? What about Bio T - is that truly a better comparison? If so, mine shot up really high after long-term clomid but I've now obviously dropped.

Never had a doctor draw SHBG, but if clomid raised it, shouldn't it have also dropped with discontinuation?

Okay, I didn't word things properly above.  Clomid (usually) will raise a guys overall total testosterone and this will raise a man's free testosterone and bioavailable testosterone.  But let's take the case of free testosterone.  Before you went on Clomid, your free testosterone as a percentage of total might be, say, 2.0%.  After you go on Clomid, your free T % might be 1.7%.  So you get a disproporpionate rise in you free testosterone, which is what I was trying to describe.  Hope that makes more sense...
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

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Re: Confused with labs, could use some advice...
« Reply #3 on: May 30, 2014, 04:29:43 pm »


PeakT

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Re: Confused with labs, could use some advice...
« Reply #4 on: May 30, 2014, 05:12:37 pm »
I split the OP's new thyroid labs here since they were interesting:

https://www.peaktestosterone.com/forum/index.php?topic=4260.0
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Peak Testosterone Forum

Re: Confused with labs, could use some advice...
« Reply #4 on: May 30, 2014, 05:12:37 pm »