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Author Topic: Low Free Testosterone  (Read 4746 times)

Anton_LowFreeT

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Low Free Testosterone
« on: August 20, 2012, 05:59:54 pm »
Hi PeakT.

First off I would just like to say great website and forum!

I am male, 38 years old, 66 kg body weight, 15% body fat.
Since April 12, I take Clomiphene Citrate (25 mg daily).
My goal is to boost testosterone production (Total+Free).

My blood test results from March 12 (in []-brackets the reference values of the laboratory):
LH  4,06 IU/l - [1,50-9,20]
FSH 4,52 IU/l [1,50-12,40]
Testosterone TOTAL 5,32 ng/ml [2,49-8,36]
Testosterone FREE 11,4 pg/ml [8,9-42,5]
SHBG 32,8 nmol/l [10-57]
DHEAS 586,5 g/dl [88,9-427]
Zinc 141 g/dl [70-130]
Selenium 181 g/dl [74-139]
Vitamin D3 38,9 ng/ml [30-70]

After this blood sample from March I have started with Clomiphene Citrate in April 25mg on a daily basis.

My blood test results from July 12 (in []-brackets the reference values of the laboratory):
LH  6,17 IU/l - [1,50-9,20]
FSH 5,64 IU/l [1,50-12,40]
Estradiol (E2) - 25,3 pg/ml [7,6-43,0]
Testosterone TOTAL 8,69 ng/ml [2,49-8,36]
Testosterone FREE 11,4 pg/ml [8,9-42,5]
SHBG 51,1 nmol/l [10-57]
DHEAS 385,4 g/dl [88,9-427]
Zinc 115 g/dl [70-130]
Selenium 194 g/dl [74-139]
PSA 0,606 ng/ml [<1,40]
Vitamin D3 56,6 ng/ml [30-70]
TSH basal 1,32 U/ml [0,44-3,77]
Free T3 3,06 pg/ml [2,00-4,40]
Free T4 1,40 ng/dl [0,93-1,71]

Total Testosterone increased from 5,32 to 8,69 ng/ml very positive.
As you can see, my Free Testosterone didnt change compared to March WHY? Still on same level.
Unfortunately, SHBG rose from 32,8 to 51,1 nmol/l.

Does that mean that SHBG is blocking the increase of Free Testosterone? Generally speaking: The increase in Total T doesnt reflect in higher Free T.

I dont understand why my Free T doesnt increase.

My questions:
- What can I do to reduce the level of SHBG?
- If I reduce the level of SHBG, my Free T should rise?

My goal is to increase my Free T above 20 pg/ml.

Many thanks. Anton

PeakT

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Re: Low Free Testosterone
« Reply #1 on: August 21, 2012, 12:45:54 am »
I'm getting a free T percentage of .23%, which just does not make sense. 

It should be about 10X that.

Also, one study shows Clomid really boost free T, so I'm not sure what's going with your #s:

"The effects of aging in normal men on bioavailable testosterone and luteinizing hormone secretion: response to clomiphene citrate"
https://digital.lib.washington.edu/dspace/handle/1773/4378

What you have to be potentially slightly more concerned about is the estradiol readings post-Clomid, which can low your T/E2 ratio:

"The Effects of Normal Aging on the Response of the
Pituitary-Gonadal Axis to Chronic Clomiphene Administration
in Men"

http://www.andrologyjournal.org/cgi/reprint/12/4/258

Again, talk to your lab and/or doc.  Let me know what you find out if you think of it:  your'e the second poster who has had this kind of thing happen.

Here's some info about SHBG and free testosterone.  However, you have to realize that once you go on a pharmaceutical (or HRT), the normal rules do not necessarily apply:

http://www.peaktestosterone.com/Free_Testosterone_SHBG


« Last Edit: August 21, 2012, 12:48:19 am by PeakT »
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If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

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Re: Low Free Testosterone
« Reply #1 on: August 21, 2012, 12:45:54 am »