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Author Topic: Clomid Disaster  (Read 25106 times)

electrify

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Clomid Disaster
« on: December 13, 2014, 06:11:11 am »
Decided to start a new thread since the other one was getting really long....

But what is up with this medication? It sort of worked for me in the beginning but now its created a disaster even after I tapered it off and have been completely off for 2 weeks.

I still have mild anxiety but now I am getting more concerned about the libido issue which in turn is making me more anxious. How long does it take for this to return? I don't want to be a 20 year old college student with low libido for a long time :(. Getting really worried about it. Part of feeling my normal self is not only eliminating the anxiety its also getting this restored to full...

E2: 39 (</= 39 pg/mL)
CortisoL: 12.7 (3.0 -22.0 mcg/dL)

My E2 isn't even that high anymore and my cortisol is alright. I don't know what the T level is yet--I'll get it in a few days but I suspect its relatively high.

Is there some quick way to reverse the Clomid damage? In a few weeks if things don't improve with the libido then what do I do?
Age:24

Osprey

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Re: Clomid Disaster
« Reply #1 on: December 13, 2014, 06:46:03 pm »
The zuclomiphene part of clomid is the much more potent part (the other being enclomiphene) and it has a much longer half life than enclomiphene. You probably felt better initially because you were feeling the effects of enclomiphene, but once the zuclomiphene part built up in your system the effect wore off. Zuclomiphene can remain detectable after 6 weeks so I think you need to wait 6-8 weeks before deciding what to do next.

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Re: Clomid Disaster
« Reply #1 on: December 13, 2014, 06:46:03 pm »


PeakT

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Re: Clomid Disaster
« Reply #2 on: December 13, 2014, 06:49:48 pm »
The zuclomiphene part of clomid is the much more potent part (the other being enclomiphene) and it has a much longer half life than enclomiphene. You probably felt better initially because you were feeling the effects of enclomiphene, but once the zuclomiphene part built up in your system the effect wore off. Zuclomiphene can remain detectable after 6 weeks so I think you need to wait 6-8 weeks before deciding what to do next.

Great info.  Didn't know the half life issue.  That shouldn't be much of an issue, though, if they've ratio'd it out right and you keep taking it.
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Kierkegaard

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Re: Clomid Disaster
« Reply #3 on: December 13, 2014, 08:55:45 pm »
The zuclomiphene part of clomid is the much more potent part (the other being enclomiphene) and it has a much longer half life than enclomiphene. You probably felt better initially because you were feeling the effects of enclomiphene, but once the zuclomiphene part built up in your system the effect wore off. Zuclomiphene can remain detectable after 6 weeks so I think you need to wait 6-8 weeks before deciding what to do next.

What Peak said.  Good stuff.
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Re: Clomid Disaster
« Reply #3 on: December 13, 2014, 08:55:45 pm »


HouKN98

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Re: Clomid Disaster
« Reply #4 on: December 14, 2014, 12:43:06 am »
The zuclomiphene part of clomid is the much more potent part (the other being enclomiphene) and it has a much longer half life than enclomiphene. You probably felt better initially because you were feeling the effects of enclomiphene, but once the zuclomiphene part built up in your system the effect wore off. Zuclomiphene can remain detectable after 6 weeks so I think you need to wait 6-8 weeks before deciding what to do next.

Great post!  This makes me feel a lot better.  I stopped clomid over a week ago, and started TRT on tuesday.  So it will probably take a full 6 weeks to flush the zuclomiphene out and allow the TRT benefits to really kick in. 

I am never taking clomid again. 

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electrify

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Re: Clomid Disaster
« Reply #5 on: December 14, 2014, 03:50:35 am »
The zuclomiphene part of clomid is the much more potent part (the other being enclomiphene) and it has a much longer half life than enclomiphene. You probably felt better initially because you were feeling the effects of enclomiphene, but once the zuclomiphene part built up in your system the effect wore off. Zuclomiphene can remain detectable after 6 weeks so I think you need to wait 6-8 weeks before deciding what to do next.

Great post!  This makes me feel a lot better.  I stopped clomid over a week ago, and started TRT on tuesday.  So it will probably take a full 6 weeks to flush the zuclomiphene out and allow the TRT benefits to really kick in. 

I am never taking clomid again.

Wow thanks haha this makes sense. I've been wondering about what happened for weeks. I've been off of it  completely for 2 weeks now and had tapered it to 12.5 mg/wk on the last dose so it might be quicker than that for me. Maybe i'll try to drink lots of water to "detox." I will also never be using that medication again and if things are bad after 4-6 more weeks then I'll just resort to TRT cause I really can't be bothered to deal with unpredictable meds like Clomid while at Uni. I had a totally random low yesterday and couldn't sleep, then today it switched back to anxiety and I had to resort to a Benzo.

@Houk How did you start TRT so early if you had just come off of Clomid? The T levels are already high after Clomid right so how can you suddenly switch to TRT--wouldn't that just increase T levels to a ridiculous amount with no benefits? Like you don't have to wait for the level to decrease or something?
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seppuku

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Re: Clomid Disaster
« Reply #6 on: December 14, 2014, 02:31:58 pm »
The zuclomiphene part of clomid is the much more potent part (the other being enclomiphene) and it has a much longer half life than enclomiphene. You probably felt better initially because you were feeling the effects of enclomiphene, but once the zuclomiphene part built up in your system the effect wore off. Zuclomiphene can remain detectable after 6 weeks so I think you need to wait 6-8 weeks before deciding what to do next.

Great post!  This makes me feel a lot better.  I stopped clomid over a week ago, and started TRT on tuesday.  So it will probably take a full 6 weeks to flush the zuclomiphene out and allow the TRT benefits to really kick in. 

I am never taking clomid again.

Wow thanks haha this makes sense. I've been wondering about what happened for weeks. I've been off of it  completely for 2 weeks now and had tapered it to 12.5 mg/wk on the last dose so it might be quicker than that for me. Maybe i'll try to drink lots of water to "detox." I will also never be using that medication again and if things are bad after 4-6 more weeks then I'll just resort to TRT cause I really can't be bothered to deal with unpredictable meds like Clomid while at Uni. I had a totally random low yesterday and couldn't sleep, then today it switched back to anxiety and I had to resort to a Benzo.

@Houk How did you start TRT so early if you had just come off of Clomid? The T levels are already high after Clomid right so how can you suddenly switch to TRT--wouldn't that just increase T levels to a ridiculous amount with no benefits? Like you don't have to wait for the level to decrease or something?

I'm beginning to wonder if some of you guys are buying dodgy clomid off the web that's actually something else. Either that or you're highly susceptible to suggestion, reading bodybuilders clomid pct reports where firstly, they're taking 100mg a day and secondly they're feeling the drop of coming off a gram of testosterone a week. Personally,  12.5mg clomid three times a week and if my libido gets any higher I'll have to think about getting a job in the porn industry.

HouKN98

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Re: Clomid Disaster
« Reply #7 on: December 14, 2014, 09:49:24 pm »
I got my clomid from a pharmacy like Walgreens, prescribed by a MD.  As legit as it gets.  And I don't read the bodybuilder forums because I want to avoid picking up irresponsible advice based on nothing more than broscience.  I actually give a shit what I do to my body :D
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electrify

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Re: Clomid Disaster
« Reply #8 on: December 15, 2014, 08:34:57 am »
Same--my Clomid was prescribed by an MD endocrinologist although he clearly didn't know what he was doing...

Being the math nerd I am--I made a simple excel spreadsheet thing to estimate the amount of Clomid left in my system (I had indicated all the days/doses I took the medication as part of CBT). Its around 12.5 mg as of now and will take 6-7 weeks to be eliminated as was said before.

Hopefully as every week passes I will get increasingly better. I think this half-life stuff also explains why the rate of my anxiety improvement seems to slow down over time.
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seppuku

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Re: Clomid Disaster
« Reply #9 on: December 15, 2014, 09:17:35 am »
I guess for some people,  it just doesn't suit them. Maybe if some day (year) in the future Androxal comes out, that will be more successful for more people.

HouKN98

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Re: Clomid Disaster
« Reply #10 on: December 15, 2014, 02:31:47 pm »
I guess for some people,  it just doesn't suit them. Maybe if some day (year) in the future Androxal comes out, that will be more successful for more people.

I think you're one of the lucky ones.
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electrify

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Re: Clomid Disaster
« Reply #11 on: December 16, 2014, 12:07:37 am »
Ok something weird is happening. My total T levels are not as high as I expected. But my free T is still high. I will be seeing a urologist soon (hopefully better than endo) and need to ask the right questions.

Total T: 581 ng/dL (250-1100 ng/dL)
Free T: 180.4 pg/mL (35.0-155.0 pg/mL)
E2: 39 pg/mL (</= 39 pg/mL)

Age:24

electrify

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Re: Clomid Disaster
« Reply #12 on: December 25, 2014, 06:37:45 am »
I'm starting to have agitation and increased anxiety this week. Feel low/unmotivated at times too. Mind is constantly racing and won't turn off. Also physical symptoms like nausea, trembling have returned and I am getting weird head pressure. For some reason the tingling is not there anymore though...

Any idea what may be happening?

 According to the dr a few weeks ago things were supposed to be coming into balance every day but I seem to be getting worse this week. Feel unmotivated again compared to last week. I'll get a test done next week by myself I guess since the dr's don't want to order one until end of January and my school is starting up in 2 weeks. So with the semester coming up its also adding to the anxiety.

One thing I haven't examined is the nutrition--I eat high glycemic foods and also don't eat as much meat in my diet.
Age:24

Dallas

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Re: Clomid Disaster
« Reply #13 on: December 25, 2014, 06:39:44 am »
high e2.  I had this happen when my free T got high as well.. I still think it was high E2

electrify

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Re: Clomid Disaster
« Reply #14 on: December 25, 2014, 06:55:03 pm »
high e2.  I had this happen when my free T got high as well.. I still think it was high E2

Hmm. My E2 was only slightly high at 39 but that was last month. I'm wondering if the T level overall is dropping back to where at was before Clomid. Morning erections are also diminishing but that could also be since insomnia is back....

Had an intense gagging attack after getting up today. Has anyone tried out Nolvadex with an AI? Is that better than Clomid? I'm so desperate for a solution cause I'm in college. Urologist also mentioned TRT depending on tests in january but was iffy about it.
Age:24

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Re: Clomid Disaster
« Reply #14 on: December 25, 2014, 06:55:03 pm »