I fell in to the trap of "required Anastrozole, 1mg per week!" and was rather miserable, this was based on standard (not sensitive) testing. I was at 34 on that test and contemplating MORE anastrozole, the Dr wanted more but .25mg EOD and I was feeling lifeless, in many ways.
I quit cold turkey the day I got myself a sensitive test that showed me at 19. I thought I'd be lower. I restarted Anastrozole 9 days later and now I only take .25mg 24hrs post injection.
I have a test coming in about 3 weeks
I can't say that having my E2 increase has done anything for me, I know I'm not emotionless and lifeless though, starting to have some upper body acne, too.