He didn't seem concerned with the PSA because it was around that value without the TRT. He did evaluate it and put me on Cipro back in November long before TRT which brought the number down a bit. He did an US and Cytoscopy which showed nothing. He said he is not concerned and at 48 the PSA is WNL.
Well, PSA is not the greatest test. Basically, with a number as high as yours, my understanding is that it is saying that you probably have either inflammation, prostatitis or actual prostate cancer. And my number went up to 6.3 from about 1.4, so I've been through the war with this. (I'm down to 1.9 per my last read - whew!) Now a high percentage of men over 40 will have prostate cancer nodules - we are just very vulnerable to this with a Western lifestyle - but I don't believe a small nodule or two will really raise your PSA. But a decent sized nodule, prostatitis and inflammation will all really raise it. I have also read that some men just tend to have higher PSA's for reasons that are poorly understood.
But, if I had a PSA in the 3's like yourself, I would work my rear off to keep everything under control - inflammation and PC in particular. It does not appear that I have prostate cancer since my PSA has gone way down and they found actual inflammation in the prostate via a biopsy along with no cancer or precancerous cells. But I pretend that I have PC, because there is a good chance that I have one of those small nodules just based on my past Western lifestyle. I'm married with three kids, so I take it seriously.
I have a considerable amount of material here if you are int'd:http://www.peaktestosterone.com/Hdr_Prostate_Vasectomy_Fertility