Peat loves telling the story of how they once treated rats with very high doses of progesterone. The technicians thought they were all dead, and threw them away. Hans Selye didn't believe they were dead, so he went to see them, and found that they were all just sleeping profoundly. Progesterone is one of the safer hormones -not saying it's completely safe-, and also has very strong sedative effects.
So I guess prometrium is also available without prescription?