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Author Topic: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole  (Read 23876 times)

surfdog

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #30 on: July 12, 2015, 08:57:53 am »
PeakT, I'd like to try the mushroom route but I'm working overseas in a tropical country a long ways from home (USA). It's not realistic for me at the moment. If it was a bananas or mangos treatment I'd be in.  8)

Hydrated, I'm doing 100 mg per week of test cyp dosed EOD sub q. I'm not doing any HCG at the moment. I was going to drop to 88mg but my total T number is 800 and I'd like to keep it there. I have lots of energy which was why I started TRT. My pre TRT readings were all around 300 to 320 and I was just feeling worn out, but still had good libido and with cialis good sex.

I started the Arimidex Friday at .25mg. I can say that last night I had better sex with my GF than I've had in quite a while. Not sure if it's placebo but as I understand it will take about a week for the liver to clear the excess estrogen. I also hear it can work in the matter of hours in blocking further conversion.

I read that a common protocol to start is 1mg a week in divided doses. I'm debating on doing that or going down to about .5 mg a week in divided doses. If I do .5 mg I need to get these pills compounded as I don't think I can make .125 pieces.

What do you think based on spending time on these boards? Is 1mg a week too much to start (would take .25 mg on shot day for a total of 1.75 over 2 weeks, so a bit less than 1mg per week)? I do plan on adding HCG back in at about 100iu EOD or so when I get done with some upcoming trips.
« Last Edit: July 12, 2015, 09:00:03 am by surfdog »

Hydranted

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #31 on: July 12, 2015, 09:20:43 am »
You may have felt an almost instant effect from the Adex since it does have a minor effect on the amount of circulating estradiol in your body.  It's main action is to block aromatization, but it does help to slightly reduce estradiol in "real time" as well.

I'd recommend keeping the dosing simple, and low.  Taking .25mg twice weekly would be a great starting point.  I really don't think that you'll need any more than that to be honest, but follow up labs (and symptom relief!) will help make that determination.

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #31 on: July 12, 2015, 09:20:43 am »


surfdog

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #32 on: July 12, 2015, 09:27:19 am »
Thanks. How you would dose .25mg twice a week when doing EOD injects?

Dr. John starts guys on AI (if they need it) the same day as an inject. That recommendation along with my understanding that Arimidex is effective for about 2 days is why I wanted to take it on inject day and EOD.

Yeah, I'd rather take less and see how it goes. In that case I'll need to compound them into .125.

Hydranted

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #33 on: July 12, 2015, 12:08:20 pm »
I'd just pick 2 days and stick with them, regardless if it's an injection day or not.  No need to over complicate it.  If your estradiol is high on an EOD protocol, it's going to roughly stay at that constant level, so the timing may not be quite as important as you think. 

If it would be easy for you to get it compounded in the desired dose, I'd do that instead.  More frequent dosing will always lead to more stable blood levels.  I think you'll be fine taking it twice per week though.  Only one way to find out.

The half life of Adex is roughly 48 hours, so it's not completely out of your system in 2 days.

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #33 on: July 12, 2015, 12:08:20 pm »


Regulus

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #34 on: August 01, 2015, 01:35:28 am »
Just an update since I started this thread.

I've been taking 0.5 mg EOD now.   While I don't have any labs yet to share, I can say that subjectively it's definitely working.   The absolute tell is that I am not getting any weepy feelings (which I was a little with the high E2), have had much higher energy levels, and sexually things are going very, very well.

Same effects I got from the edible fungus, just a heck of a lot easier to take a half-pill every other day, and dosing consistency of course as well.
Late 40's, on TRT since 2011.
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Regulus

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #35 on: September 14, 2015, 11:51:29 am »
Just an update since I started this thread.

I've been taking 0.5 mg EOD now.   While I don't have any labs yet to share, I can say that subjectively it's definitely working.   The absolute tell is that I am not getting any weepy feelings (which I was a little with the high E2), have had much higher energy levels, and sexually things are going very, very well.

Same effects I got from the edible fungus, just a heck of a lot easier to take a half-pill every other day, and dosing consistency of course as well.

Experiment update. 

Finally was able to get labs.   Before anastrazole I was at 87, which inspired me to start using it.

After three months, my estradiol tested at <5.  So I guess the stuff works. 

Yeah, I know that is way too low....

I suspected it might have taken me too low because after the initial month of feeling fantastic and incredibly horny, things started to settle down.   However, I have not experienced any really bad effects.   Morning wood has become much less frequent, but in general I feel fine. 

So this might be a little tough to titrate, since half a pill every other day crashed me. 

I am stopping entirely for two weeks, and then will try a half pill twice a week (just on injection days).   The good news is that since I went so low, insurance will approve labs much sooner than the three months I had to wait first go round, so a month after starting the new dose I will have data. 

Hopefully this is short term anyway.  I've got about 25 pounds left to lose now, which won't be easy, but the hope that that might solve the aromatization issue in combination with the dietary stuff that I do believe works is extra motivation.
Late 40's, on TRT since 2011.
Test cyp 50 mg twice per week
Vegan and loving it since late 2015

PeakT

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #36 on: September 14, 2015, 05:01:24 pm »
Just an update since I started this thread.

I've been taking 0.5 mg EOD now.   While I don't have any labs yet to share, I can say that subjectively it's definitely working.   The absolute tell is that I am not getting any weepy feelings (which I was a little with the high E2), have had much higher energy levels, and sexually things are going very, very well.

Same effects I got from the edible fungus, just a heck of a lot easier to take a half-pill every other day, and dosing consistency of course as well.

Experiment update. 

Finally was able to get labs.   Before anastrazole I was at 87, which inspired me to start using it.

After three months, my estradiol tested at <5.  So I guess the stuff works. 

Yeah, I know that is way too low....

I suspected it might have taken me too low because after the initial month of feeling fantastic and incredibly horny, things started to settle down.   However, I have not experienced any really bad effects.   Morning wood has become much less frequent, but in general I feel fine. 

So this might be a little tough to titrate, since half a pill every other day crashed me. 

I am stopping entirely for two weeks, and then will try a half pill twice a week (just on injection days).   The good news is that since I went so low, insurance will approve labs much sooner than the three months I had to wait first go round, so a month after starting the new dose I will have data. 

Hopefully this is short term anyway.  I've got about 25 pounds left to lose now, which won't be easy, but the hope that that might solve the aromatization issue in combination with the dietary stuff that I do believe works is extra motivation.

Since you're a veteran, I'm sure you know this but:

--You can get compounded anastrozole in liquid and other forms so that you can get a smaller dose.

--Some guys a re very sensitive to it.

--You don't want to stay low for long as it can lead to bone loss.
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Regulus

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #37 on: September 14, 2015, 11:56:11 pm »
Yep, Peak, know all that, but thanks anyway.  I follow a pretty informative site.  :-).

Mostly posting to share the info that

(A) it can be incredibly powerful stuff.  I went from twice the top of the range to undetectable on a pretty low dose

(B) "crashing estradiol", while not something to take lightly because, yeah, we do need the stuff, doesn't necessarily lead to a horror story of symptoms.  It does for some, but sure hasn't for me. 
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PeakT

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #38 on: September 15, 2015, 01:19:35 am »
Yep, Peak, know all that, but thanks anyway.  I follow a pretty informative site.  :-).

Mostly posting to share the info that

(A) it can be incredibly powerful stuff.  I went from twice the top of the range to undetectable on a pretty low dose

(B) "crashing estradiol", while not something to take lightly because, yeah, we do need the stuff, doesn't necessarily lead to a horror story of symptoms.  It does for some, but sure hasn't for me.

Usually, it's a few weeks of misery and then all is back to normal.
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

bolide

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #39 on: September 16, 2015, 05:04:07 am »
What type of mushrooms were you eating?

Regulus

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #40 on: September 16, 2015, 11:23:50 am »
What type of mushrooms were you eating?

Regular grocery store brown button (cremini, or "baby portabella").  It's the same species as the white ones, and the white ones actually have tested a little more effective, but I like the flavor of the brown better.
Late 40's, on TRT since 2011.
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PeakT

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #41 on: September 16, 2015, 03:40:37 pm »
What type of mushrooms were you eating?

Regular grocery store brown button (cremini, or "baby portabella").  It's the same species as the white ones, and the white ones actually have tested a little more effective, but I like the flavor of the brown better.

So, if you eat a decent amount of broccoli, it basically switches the bad estrogen metabolites to the good.  Do these mushrooms to the same?  Any idea?
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Regulus

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #42 on: September 16, 2015, 04:58:23 pm »
What type of mushrooms were you eating?

Regular grocery store brown button (cremini, or "baby portabella").  It's the same species as the white ones, and the white ones actually have tested a little more effective, but I like the flavor of the brown better.

So, if you eat a decent amount of broccoli, it basically switches the bad estrogen metabolites to the good.  Do these mushrooms to the same?  Any idea?

As I understand it, and I could be wrong, the view seems to be that they are an aromatase inhibitor.
Late 40's, on TRT since 2011.
Test cyp 50 mg twice per week
Vegan and loving it since late 2015

PeakT

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Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #43 on: September 16, 2015, 08:47:33 pm »
What type of mushrooms were you eating?

Regular grocery store brown button (cremini, or "baby portabella").  It's the same species as the white ones, and the white ones actually have tested a little more effective, but I like the flavor of the brown better.

You're spot on.  I was just too lazy to look it up:

http://cancerres.aacrjournals.org/content/66/24/12026.short

"Anti-Aromatase Activity of Phytochemicals in White Button Mushrooms (Agaricus bisporus)"

So, if you eat a decent amount of broccoli, it basically switches the bad estrogen metabolites to the good.  Do these mushrooms to the same?  Any idea?

As I understand it, and I could be wrong, the view seems to be that they are an aromatase inhibitor.
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Peak Testosterone Forum

Re: Mushrooms Probably Lowered My Estradiol But Switching to Anastrazole
« Reply #43 on: September 16, 2015, 08:47:33 pm »