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Author Topic: DHEA - Dehydroepiandrosterone  (Read 9716 times)

duke11

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DHEA - Dehydroepiandrosterone
« on: January 10, 2012, 04:13:07 pm »
what are your thoughts on using this to treat ED? :-\

PeakT

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Re: DHEA - Dehydroepiandrosterone
« Reply #1 on: January 11, 2012, 03:35:20 am »
Remember Mark McGwire?  Well, he was taking androstenedione.  One of the risks with this prohormone is that is can also convert to estrone.

DHEA actually converts to androstenedione and so you open this same estrogen pathway.  Furthermore, the androstenedione will also partially convert to testosterone and the testosterone can aromatize to estradiol, the "bad" estrogen.  So the bottom line is that you have two estrogen pathways activated when taking DHEA and so the question is whether or not you get higher T proportionally.

Well, actually, that turns out not to be the question, because DHEA seems to have no significant effect on either T or E according to this study:

http://jap.physiology.org/content/87/6/2274.short
"Effect of oral DHEA on serum testosterone and adaptations to resistance training in young men"

For this reason I do not know of many bodybuilders or strength athletes taking DHEA - it just doesn't do much of anything to get excited about.

Now DHEA does have a couple of interesting possibilites, but it has kind of died off in the supplement world due to lackluster results on many fronts...

Bottom line imo is that there are much better supplements for ED.
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

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Re: DHEA - Dehydroepiandrosterone
« Reply #1 on: January 11, 2012, 03:35:20 am »


davcir

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Re: DHEA - Dehydroepiandrosterone
« Reply #2 on: November 13, 2014, 11:57:48 pm »
I have come across articles about the relationship between DHEA and cortisol. The suggestion being that they can  see saw in opposition to each other.

http://www.drdebe.com/articles/dhea-the-real-story

Suggestion here  is that Cortisol takes over and DHEA production is suppressed and can need a form of "reboot".

http://articles.mercola.com/sites/articles/archive/2000/08/27/adrenals

Im going to keep " digging " ( including adding DHEA to my next blood work ) .

17 Oct

FSH 4.5 mUI/ml
Estradiol 17- Beta 30.2 pg/ml
Testosterone 3.8 ng/ml
Insulin 6.5 μUI/ml

TSH 1.582 μUI/ml
T4 Free .98 ng/dl
T3 Free  3.3 pg/ml

BMI 26 / 80 Kilos
Age 38


20 November

LH 3.4 MUI/ml ( 1.5 - 9.3 )
Prolactin 4.7ng /ml ( 2.1 -17-7 )
Testosterona 6.4 ng/ml
Free Test.      25.93 pg/ml ( 10 - 42 )
DHEA 2.94 ng/ml (1.4 - 12-5 )
DHEA Sulfate 278 ug/dl
Cortisol 6.5 ug/dl

Kierkegaard

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Re: DHEA - Dehydroepiandrosterone
« Reply #3 on: November 14, 2014, 12:16:03 am »
I have come across articles about the relationship between DHEA and cortisol. The suggestion being that they can  see saw in opposition to each other.

http://www.drdebe.com/articles/dhea-the-real-story

Suggestion here  is that Cortisol takes over and DHEA production is suppressed and can need a form of "reboot".

http://articles.mercola.com/sites/articles/archive/2000/08/27/adrenals

Im going to keep " digging " ( including adding DHEA to my next blood work ) .

This is true, so much so that your level of DHEA can be used to investigate further for possible adrenal problems: if DHEA is off the charts high, this could indicate underfunctioning adrenals, and vice versa.  And like Peak said, DHEA converts to estrogens.  I know this from experience, because my DHEA is high (which is healthwise a good thing), but is likely responsible for my overconversion of testosterone to estradiol, and/or my sensitive to estradiol -- hence my difficulty finding my sweet spot where T is high enough but estradiol isn't too high. 
"The same thing that makes you live can kill you in the end." -- Neil Young

March 2014: Dx low T (158ng/dl)
September 2015: Dx hypothyroidism, other adrenal hypofunction
2016: chronic fatigue, unspecified

Depression and anxiety guide: http://www.peaktestosterone.com/Help_Anxiety_Depression

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Re: DHEA - Dehydroepiandrosterone
« Reply #3 on: November 14, 2014, 12:16:03 am »


Tfan

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Re: DHEA - Dehydroepiandrosterone
« Reply #4 on: November 14, 2014, 12:30:57 am »
I have come across articles about the relationship between DHEA and cortisol. The suggestion being that they can  see saw in opposition to each other.

http://www.drdebe.com/articles/dhea-the-real-story

Suggestion here  is that Cortisol takes over and DHEA production is suppressed and can need a form of "reboot".

http://articles.mercola.com/sites/articles/archive/2000/08/27/adrenals

Im going to keep " digging " ( including adding DHEA to my next blood work ) .

Peak Mike Mahler is a big fan of natural (not supplemented) dhea because it is a calming anti cortisol hormone.
Does anyone know if we can increase it with Magnesium??? Saw some talks on the web
Age 48
Tribullus

PeakT

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Re: DHEA - Dehydroepiandrosterone
« Reply #5 on: November 14, 2014, 01:27:43 am »
I have come across articles about the relationship between DHEA and cortisol. The suggestion being that they can  see saw in opposition to each other.

http://www.drdebe.com/articles/dhea-the-real-story

Suggestion here  is that Cortisol takes over and DHEA production is suppressed and can need a form of "reboot".

http://articles.mercola.com/sites/articles/archive/2000/08/27/adrenals

Im going to keep " digging " ( including adding DHEA to my next blood work ) .

Peak Mike Mahler is a big fan of natural (not supplemented) dhea because it is a calming anti cortisol hormone.
Does anyone know if we can increase it with Magnesium??? Saw some talks on the web

Natural?  What do you mean by that?  You mean doing lifestyle changes or are you referring to the delivery system or what?

THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

davcir

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Re: DHEA - Dehydroepiandrosterone
« Reply #6 on: November 14, 2014, 07:27:48 am »
Sorry perhaps it wasnt cool to go posting urls . At some point ill look for actual " studies " . From  a low T perspective all i can find is bodybuilders who take it with some form of AI to boost T. Its on the Wada banned list among others .. its not there for clearing up ones skin.
17 Oct

FSH 4.5 mUI/ml
Estradiol 17- Beta 30.2 pg/ml
Testosterone 3.8 ng/ml
Insulin 6.5 μUI/ml

TSH 1.582 μUI/ml
T4 Free .98 ng/dl
T3 Free  3.3 pg/ml

BMI 26 / 80 Kilos
Age 38


20 November

LH 3.4 MUI/ml ( 1.5 - 9.3 )
Prolactin 4.7ng /ml ( 2.1 -17-7 )
Testosterona 6.4 ng/ml
Free Test.      25.93 pg/ml ( 10 - 42 )
DHEA 2.94 ng/ml (1.4 - 12-5 )
DHEA Sulfate 278 ug/dl
Cortisol 6.5 ug/dl

Tfan

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Re: DHEA - Dehydroepiandrosterone
« Reply #7 on: November 14, 2014, 08:31:10 am »
I have come across articles about the relationship between DHEA and cortisol. The suggestion being that they can  see saw in opposition to each other.

http://www.drdebe.com/articles/dhea-the-real-story

Suggestion here  is that Cortisol takes over and DHEA production is suppressed and can need a form of "reboot".

http://articles.mercola.com/sites/articles/archive/2000/08/27/adrenals

Im going to keep " digging " ( including adding DHEA to my next blood work ) .

Peak Mike Mahler is a big fan of natural (not supplemented) dhea because it is a calming anti cortisol hormone.
Does anyone know if we can increase it with Magnesium??? Saw some talks on the web

Natural?  What do you mean by that?  You mean doing lifestyle changes or are you referring to the delivery system or what?

Yes lifestyle changes that could enhance dhea by hindering cortisol production. So, it is not taking dhea to decrease cortisol, but enhancing the dhea pathway through decresing stress.
Age 48
Tribullus

Peak Testosterone Forum

Re: DHEA - Dehydroepiandrosterone
« Reply #7 on: November 14, 2014, 08:31:10 am »