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Author Topic: Has anybody thought about "cycling" dosages of Testosterone?  (Read 6817 times)

Kierkegaard

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Re: Has anybody thought about "cycling" dosages of Testosterone?
« Reply #15 on: January 06, 2016, 04:41:49 am »

SHBG = 27.1 range 19.3 to 76.4.

Someday I want to try low dose IM injections on a weekly schedule. Not there yet though. Doc has me trying HCG mono again.

Got it.  Hey, it takes some experimenting and some men have preferred weekly.  One thing - and maybe this is where you were headed - about weekly is that as those T levels plummet at the tend of the week, it may let the ol' dopamine receptors normalize?  How's that for a wild-eyed theory?

I don't think that's wild-eyed!  At the same time, because you're injecting weekly, you'll get a higher dose at the beginning of the week.  So it seems like the more infrequent your injections, the more of an overwork on dopamine receptors (first few days as T levels are highest) followed by a rest of D receptors (as T levels are lowest); whereas with more frequent injections you have more stable levels, meaning any dopamine desensitization will be a function of overall stable amount of T: as you have higher T levels you're pounding D receptors harder more continuously (because of the smoothness of the curve with more frequent injections and less fluctuations), whereas with more modest (e.g., 600-700 ng/dl) total T levels you're not hitting D receptors as hard even though it's a consistent hit.  So maybe this is another reason why physiological doses are better than supraphysiological.  Does that make sense?

Yeah, I was thinking about one of your posts and think about a healthy young guy with peak am T of 900 ng/dl.  His testosterone probably collapse to about 550 in the evening, so his average is about 700 with a range of aoubt 200 on either side.

Now, if you look at my T, it is very similar doing subQ EOD.  This is something I actually want to test sometime.

Maybe this is an argument for the shorter estered testosterone types, like propionate, or doing gels, which mimic daily endogenous fluctuations.  Just now thought of that...
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PeakT

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Re: Has anybody thought about "cycling" dosages of Testosterone?
« Reply #16 on: January 06, 2016, 03:27:06 pm »

Maybe this is an argument for the shorter estered testosterone types, like propionate, or doing gels, which mimic daily endogenous fluctuations.  Just now thought of that...

Sure, I've heard of some of the low SHBG guys using propionate successfully.  Don't know how common it is.  It looks like it has a 2-3 day half life.
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Re: Has anybody thought about "cycling" dosages of Testosterone?
« Reply #16 on: January 06, 2016, 03:27:06 pm »