Quantcast

Author Topic: Aromasin Dangers  (Read 4854 times)

JackAndy

  • Hero Member
  • *****
  • Posts: 1233
    • View Profile
Aromasin Dangers
« on: January 31, 2013, 08:08:08 am »
http://jcem.endojournals.org/content/88/12/5951.full.pdf

From the abstract:
Quote from: NELLY MAURAS, JOHN LIMA, DEVAL PATEL, ANNIE RINI, ENRICO DI SALLE, AMBROSE KWOK,
AND BARBARA LIPPE
Exemestane suppressed plasma estradiol comparably with either dose [25 mg, 38% (P <0.002); 50 mg, 32% (P < 0.008)], with a reciprocal increase in
testosterone concentrations (60% and 56%; P < 0.003 for both). Plasma lipids and IGF-I concentrations were unaffected by treatment.
This work was supported by a grant from Amersham Pharmacia Biotech

They are studying this aromatase inhibitor for use in treating short stature in pre-pubescent boys. They are trying to show how this drug is safe and won't mess with your cholesterol, which is a something that can happen when your estrogen drops too low. But they only did the study for 24 hours so I don't think it really shows anything.
« Last Edit: January 31, 2013, 09:27:59 pm by PeakT »
Age:29
5'11" 190 lbs
150mg Test-E/week

PeakT

  • Administrator
  • Hero Member
  • *****
  • Posts: 38446
    • View Profile
    • Peak Testosterone
Re: Aromasin Dangers
« Reply #1 on: January 31, 2013, 08:05:21 pm »
Thanks for the heads up.  The other name for this is Exemestane? 

Did you notice it says it is an irreversible aromatase inhibitor?

http://en.wikipedia.org/wiki/Exemestane

This reminds me of 6-OXO:

http://www.peaktestosterone.com/Estrogen_Controlling  (See #3.)
« Last Edit: June 27, 2013, 06:58:57 pm by PeakT »
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Peak Testosterone Forum

Re: Aromasin Dangers
« Reply #1 on: January 31, 2013, 08:05:21 pm »


JackAndy

  • Hero Member
  • *****
  • Posts: 1233
    • View Profile
Re: Aromasin Dangers
« Reply #2 on: February 01, 2013, 09:18:10 am »
I'm not sure if it's actually permanent, actually I'm almost certain it's not. I was a bit confused by the term "suicide inhibitor" also. But either more enzymes come back eventually or something. It is very interesting research though.
Age:29
5'11" 190 lbs
150mg Test-E/week

PeakT

  • Administrator
  • Hero Member
  • *****
  • Posts: 38446
    • View Profile
    • Peak Testosterone
Re: Aromasin Dangers
« Reply #3 on: February 01, 2013, 05:25:23 pm »
I'm not sure if it's actually permanent, actually I'm almost certain it's not. I was a bit confused by the term "suicide inhibitor" also. But either more enzymes come back eventually or something. It is very interesting research though.

MODERATOR UPDATE:  Yes, you should rebuild those enzymes in a few weeks.
« Last Edit: July 01, 2013, 08:00:34 am by PeakT »
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Peak Testosterone Forum

Re: Aromasin Dangers
« Reply #3 on: February 01, 2013, 05:25:23 pm »


JackAndy

  • Hero Member
  • *****
  • Posts: 1233
    • View Profile
Re: Aromasin Dangers
« Reply #4 on: February 02, 2013, 02:46:43 am »
That study was talking about how the effects are temporary even. I just did a google search and found some sites where people were explaining that the enzyme comes back eventually, which makes sense.

Here's something from a book:
http://books.google.co.jp/books?id=cWbYxSfKN3cC&pg=PA168&lpg=PA168&dq=are+suicide+inhibitors+permanent&source=bl&ots=NqEJL22rmS&sig=gmV19_xAEcZwcsZdCGvbfGrazKo&hl=en&sa=X&ei=unwMUYrbE8yakgWakoGoDw&ved=0CGYQ6AEwCQ

That makes more sense right?
Age:29
5'11" 190 lbs
150mg Test-E/week

PeakT

  • Administrator
  • Hero Member
  • *****
  • Posts: 38446
    • View Profile
    • Peak Testosterone
Re: Aromasin Dangers
« Reply #5 on: February 02, 2013, 04:09:25 am »
Takes two to three week I guess.
« Last Edit: June 27, 2013, 06:59:31 pm by PeakT »
THE MOST COMPREHENSIVE BOOK ON TRT/TESTOSTERONE:
https://www.amazon.com/Natural-Versus-Testosterone-Therapy-Myer/dp/1523210532/ref=sr_1_1?ie=UTF8&qid=1499116128&sr=8-1&keywords=natural+versus+testosterone+therapy
And check out my New Peak Testosterone Program: http://www.peaktestosterone.com/peak_testosterone_program
If you are on medications or have a medical condition, always check with your doctor first before making any lifestyle changes or taking new supplements.  And low testosterone is a medical condition.

Peak Testosterone Forum

Re: Aromasin Dangers
« Reply #5 on: February 02, 2013, 04:09:25 am »