Hi my friends. It has been a while since I last posted here. For some reason, being on a high fat diet and losing weight kinda made the low-T related symptoms go away. T went up 10% in the last year; not a ridiculous raise but since I have been asymptomatic, I figured all was good.
I have been on a high fat diet (specifically the Bulletproof diet) since January 2015. Cholesterol numbers have been high, but I never had any inflammation (according to CRP tests). Also, A1c is at a nice 4.7%. I thought all was well.
I have been interested in getting more advanced testing done so over the last couple of months I've done a bunch more tests. Here is the good, the bad, and the ugly:
LDL - 173 mg/dL
HDL - 55 mg/dL
Triglycerides - 75 mg/dL
Total Cholesterol - 234 mg/dL
CRP - 0.34 mg/dL
apoB - 127 mg/dL
Homocysteine - 11.70 mcmol/L
Lipoprotein (a) - 59 mg/dL (HIGH)
Lp-PLA2 - 339 ng/mL (HIGH)
LDL-P - 1600 (HIGH)
Those last three numbers are high, so I was worried. Even though CRP was low, that Lp-PLA2 number is high and scary. One possible hypothesis is that, Lp-PLA2 levels increase with gum disease, and I have a bit of gingivitis. I hope this is it but who knows? Will report back after I get a deep cleaning at the dentist and my gum inflammation goes down.
Some more light on the NMR test I got - I have a low small LDL-P at 389 (which puts me around the low 20th percentile) and a high HDL-P of 34.1(which puts me at around the 75th percentile of high). Also, my LDL size is on the Large pattern A side. So this doesn't look terrible IMO.
Not to stop here, I went ahead and got a calcium score CT scan:
CALCIUM SCORE (AGATSTON)
Which looks low but I was told was interpreted as "Minimal coronary artery calcification, advanced for age." My cardiologist said that LAD looks like a 50 year old's (I am 30).
Anyway, sorry for the huge dump of info, but I wanted to hear what you guys had to say about my numbers. Many may jump immediately to the high fat diet as the culprit for all for all of this, but 5 years ago I had massive insulin resistance and weighed 50lbs more. Was damage done then and is it getting better? Is the damage happening now? I have no idea since I only have a snapshot in time, no additional results to compare to.
Also, I did 23andme and found out my APOE status is e3/e4, which has some LDL implications as well. I'm not sure what to make of all this, but my cardiologist says I should stop my high fat diet and use a station. Curious to hear your thoughts guys.