Muscular male body and testosterone hormone formula. Concept of a strength workout and anabolic steroids usage.

Ways to Raise Free Testosterone

Some researchers believe that free testosterone is the only testosterone that really counts, since it is the testosterone ready and able to actually “work” on your tissues. And there is a lot of truth to this. The reason is that about two thirds of non-free, or bound testosterone is actually chemically bonded to a protein called Sex Hormone-Binding Globulin (SHBG) and about 1/3 to a protein called albumin.  Therefore, according to one school of thought, only a small percentage (about 2 percent) is actually free to supercharge our brains, blood, muscles, sex lives and all the other things we associate with testosterone. 

Well, kind of.

  It turns out that the testosterone bound to albumin is actually only bonded loosely and is readily available to do work on your tissues.  In fact, researchers have come up with the following formula:

Bioavailable Testosterone = Albumin-Bonded Testosterone + Free Testosterone

And they point out that it is really bioavailable testosterone that is the true free testosterone.  Furthermore, still other experts counter that total testosterone is really the better number, because it acts as reserve or bank to build from.

Well, I will leave that debate for the men in white, but, in the meantime, it’s best to realize that free testosterone is an incredibly important number for men to monitor and maintain.

So what then controls your free testosterone?  It turns out that your level of albumin is relatively fixed with minimal fluctuation in most men.  However, SHBG can vary widely and lab results clearly show that as SHBG goes up, the percentage of free testosterone as a percentage of total goes down and, as SHBG goes down, the percentage of free testosterone goes up.  Thus, it is SHBG that has tremendous control over free testosterone.

Normal aging, as many of us know all too painfully, leads to substantial drops in androgens such as testosterone and a corresponding rise in SHBG.  Think how ugly this is:  decreasing testosterone leads to increasing SHBG which leads to decreased free testosterone.  And, practically speaking, low free testosterone levels will yield low testosterone symptoms just as surely as low total testosterone will.

There are also many other reasons for low and high SHBG, including liver dysfunction, estradiol levels, thyroid function and much more.  I cover these in my links on Low SHBG and High SHBG.

So how do you know if your free testosterone is low?  It starts with a simple test from your doctor.  You sometimes have to ask for this, as some doctors just stick with total testosterone.  Generally, free testosterone is given as a percentage of total testosterone, the typically acceptable range according to the lab listed as 1.5%-2.5%.

NOTE:  Men on HRT (Hormone Replacement Therarpy or testosterone therapy) will often have an elevated free testosterone percentage, because HRT tends to lower SHBG. Also, some men have low SHBG even before starting HRT. These men often have great difficulty with achieving successful results from testosterone therapy for reasons that are not totally understood.

Let me give you 10 Natural Ways to Lower SHBG and Raise Free Testosterone:

1) Testosterone and Lowering Estradiol.  On this page, I’ll show some ways to uniquely raise free testosterone levels.  However, the most straightforward way to raise free testosterone levels is by raising total testosterone levels. In general, as you raise total testosterone, free testosterone tends to rise with it.  I have already created a page with 40+ Ways to Raise Testosterone Naturally.  Again, though, on this page we’ll look at some ways to raise your percentage of free testosterone (out of total testosterone).

Similarly, if you can lower your estradiol levels, you can generally get a boost in total and free testosterone.  Research shows that normal aging as well as an increase in adipose – that’s a nice way of saying fat – tissue leads to ever increasing levels of the estrogens. And here’s the key:  increasing estrogen leads to increasing SHBG, which will lower your free testosterone as a percentage of your total.  Please read the important link on How to Control Estrogen.

2) Protein-to-Carbohydrate Ratio. The protein/carbohydrate ratio has an interesting effect on free testosterone and SHBG. Several studies have shown that increasing carbs versus protein boosts total testosterone. However, before you start pounding granola bars, one study found that increasing the protein/carb ratio not only increased total testosterone but also SHBG. [4] This means that free testosterone may not have been increased significantly because of SHBG’s opposing effects. (Increasing the protein to carbohydrate ratio also increased cortisol, a fact I cover elsewhere on this site.)

3) DHEA.  Researchers examined untrained young and middle males and found that giving them 50 mg of DHEA daily raised their free testosterone significantly.  They also noted that normally HIIT substantially lowers testosterone, but with the DHEA no such decrease in free testosterone at least occurred.  [7] There are warnings out there that DHEA can increase estradiol disproportionately, but I have seen no actual research evidence of this.  The real concern with DHEA is more brain-related. Ray Peat, in particular, has noted:

“One study has found that the only hormone abnormality in a groupt of Alzheimers patients’ brains was an excess of DHEA. In cell culture, DHEA can cause changes in glial cells resembling those seen in the aging brain. These observations suggest that DHEA should be used with caution. Supplements of pregnenolone and thyroid seem to be the safest way to optimize DHEA production.”  In spite of this, DHEA seems to be widely used in the alternative and anti-aging communities.  Do your own research and talk to your doc is all I can say.

CAUTION:  Low SHBG men should not lower their SHBG further.  See my page on The Risks and Causes of Low SHBG for more information.

REFERENCES:

1) J Korean Diabetes Assoc, 1998 Sep,22(3):328-337

2) Planta Med, 1995 Feb, 61(1):31-32; Fortschr Med, Nov 10 1996, 114(31):407-411; Z Naturforsch [C], 1995 Jan-Feb,50(1-2):98-104

3) Clin Endocrinol (Oxf), 2009 Dec 29, [Epub ahead of print], “Association of vitamin D status with serum androgen levels in men”

4) Life Sciences, May 4 1987, 40(18)1761-1768, “Diet-hormone interactions: Protein/carbohydrate ratio alters reciprocally the plasma levels of testosterone and cortisol and their respective binding globulins in man”

5) Phytomedicine, 2003, 10(5):405-15, “Modulatory effect of Urtica dioica L. (Urticaceae) leaf extract on biotransformation enzyme systems, antioxidant enzymes, lactate dehydrogenase and lipid peroxidation in mice”

6) http://robthoburn.wordpress.com/2011/02/02/boron-increases-testosterone-again/

7) Eur J Appl Physiol, 2013 Jul, 113(7):1783-92, “Effect of acute DHEA administration on free testosterone in middle-aged and young men following high-intensity interval training.

8) http://raypeat.com/articles/articles/three-hormones.shtml

9) Br J Sports Med, 2003, 37(5), “THE ERGOGENIC EFFECTS OF EURYCOMA LONGIFOLIA JACK: A PILOT STUDY”

10)  http://www.prosource.net/content/articles/Articles-by-ProSource/tribulus-real-anabolic-alternative

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