Maybe you are a newbie and have no idea what I am talking about. If so, I can only tell you that, as time goes on, you may not feel as good as you believe you could or perhaps experience a side effect of your protocol. That’s when you’ll want to understand a bit more about how the testosterone you are using behaves, and the charts below will help you get a general idea.
Please keep in mind that testosterone levels are affected by many factors and these charts are just dealing in averages. Here are just a couple of examples:
–If you are on topicals, the amount of testosterone that you absorb through your skin is quite variable. Some men go on Androgel, for example, and their testosterone rockets up to 900 ng/dl. Other man will get almost no change whatsoever and may be below 400 ng/dl. And, when it comes to testosterone injections, low and high SHBG can significantly affect the half life of the ester you are dealing with.
–Low SHBG men tend to have a much lower half life and often struggle getting “dialed in” with TRT.
Of course, this chart of Fortesta could not be more different than that of undecanoate – see below – peaking at just 4 hours post-application and then rapidly tapering off afterwards. By 10 hours after the application, you are pretty much hypogonadal again. Please note that this (from what I can tell) is showing testosterone levels is someone just starting on Fortesta. See the Androgel chart below for what happens when you have been on a topical for about 2-3 weeks. (It takes 2 – maybe 3 weeks for steady state testosterone levels to be achieved on a cream or gel.)
Here is a sample chart resulting from the typical dosage of 750 mg (3 ml):
As you can see, you peak after about one week and after just four weeks you have dropped down to 500 ng/dl. Below this level, many men will not do that well – been there! (I did a round of pelletes before I went on testosteorne cypionate.)
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Now this chart shows something much more useful that the Fortesta chart in my opinion. In this case, they are showing testosterone levels 30 days into using Androgel. Of course, in that case one has reached a steady state, stable testosterone level, which is why the baseline testosterone levels above are so much higher. For example, the average testosterone of the men prior to Andrgel was around 300 ng/dl and steady state levels are in the upper 500’s and upper 700’s with 5 and 10 milligrams of Androgel, respectively.
1) FORTESTA- testosterone gel, metered; Endo Pharmaceuticals Inc., HIGHLIGHTS OF PRESCRIBING INFORMATION; These highlights do not include all the information needed to use FORTESTA safely and effectively. See full prescribing information for FORTESTA; FORTESTA (testosterone) Gel for topical use CIII, Initial U.S. Approval: 1953
2) ANDROGEL Product Monograph, Date of Revision: January 28, 2015 ; Control No. 178980
3) Journal of Andrology, 33(5), Sep/Oct 2012, “Pharmacokinetic Evaluation and Dosing of Subcutaneous Testosterone Pellets”, https://onlinelibrary.wiley.com/doi/10.2164/jandrol.111.016295/pdf
4) Endocrine J, 2006, 53(3):305-310, “Hormone Profiles after Intrasmuscular Injection of Testosterone Enanthate in Patients with Hypogonadism”, https://www.jstage.jst.go.jp/article/endocrj/53/3/53_3_305/_pdf